Dartmouth Medical School lab blends DNA and technology to aid in crime-solving
...men will be emphasized in the training courses. In order to ensure that all clinical information is compreh...men will be emphasized in the training courses. In order to ensure that all clinical information is comprehensive and up-to-date, IML is collaborating with l...Asthma gene clusters identified
...putational resources with medicine and genetics in order to customize care for patients based on the patient's individual genetic makeup. "Dr. Hershey's research is a good example of research that we believe will benefit patients, based on the use of novel algorithms and analysis from computational medicin...Circles of DNA might help predict success of stem cell transplantation
...tances stimulate T cells to divide and multiply in order to form an attacking army. However, the sjTRECs don't multiply when the original T cells divide and multiply. Instead, the more T cells that are produced in the blood as the parent cells containing sjTRECs divide and produce daughter cells, the more ...Experimental domestication of foxes yields clues to cognitive evolution
...mestication on the social intelligence of foxes in order to address this question of how social problem solving evolves. Recently, it was found that during domestication dogs evolved an unusual ability to communicate with humans: dogs appear to be more skilled at reading human social cues than wolves and e...New RNA polymerase discovered in plants
...y copying a template of DNA genetic information in order to make RNAs that encode proteins or that function directly in the cell. Biologists have studied three kinds of RNA polymerase for decades in organisms ranging from brewer's yeast to humans. In all eukaryotes, the RNA polymerases Pol I, II, and I...Study finds markers for premature birth risk at the molecular level
...lic processes occurring in the amniotic fluid), in order to identify which women who have experienced preterm labor are also at risk for delivering a premature baby. With nearly one in eight babies in the U.S. born prematurely every year, and the problem of premature birth increasing, the need for tools t...JCI Table of Contents, March 1, 2005
...on of IRS-1 and IRS-2 specifically in the liver in order to determine the roles of these molecules in the metabolism of normal mice. Knockdown of both IRS-1 and IRS-2 led to symptoms of the metabolic syndrome, including insulin resistance, glucose intolerance, and fatty liver. The authors also discovered ...Rat brain's executive hub quells alarm center if stress is controllable
...ex area (medial prefrontal cortex), seat of higher order functions, such as problem-solving and learning from experience. These signals are sent via the chemical messenger serotonin, which is involved in mood regulation and in mediating the effects of the most widely prescribed antidepressants. The medial ...UCLA scientists transform HIV into cancer-seeking missile
... protein that makes fireflies glow to the virus in order to track its journey from the bloodstream to new t...llows the tumor to continue growing unchecked." In order to track the carrier's journey, the scientists added luciferase the protein that makes fireflies gl...Scientists document complex genomic events leading to the birth of new genes
...domain-containing proteins). By analyzing the gene order around the RanBP2 and GCC2 genes, Bork's team was able to reconstruct the genomic rearrangements leading to the formation of the ancestral RGP locus. These events included a combination of duplication, inversion, partial deletion, and domain acquisi...Why do insects stop 'breathing'? To avoid damage from too much oxygen, say researchers
.... "We propose that most insects stop breathing in order to lower their internal oxygen concentration to physiologically safe levels, and that they then substantially reduce gas exchange to maintain the oxygen at these safe values," Bradley said. "This hypothesis explains the respiratory pattern of insects...Alcohol's effects on gene expression in the central nervous system
...estigators working with different animal models in order to identify the multiple genetic factors that contribute to the risk for alcoholism and alcohol abuse."...Embryonic stem cells treated with growth factor reverse hemophilia in mice
...proach may not only be beneficial, but required in order to solve complex problems such as these in medicine." Although a number of questions need to be answered, this work has great potential for future applications, not only as a novel therapeutic possibility for hemophilia but also for other genetic or ...Amino acids in nectar enhance butterfly fecundity: A long awaited link
... resulted in a spectacular diversity of plants. In order to entice pollinators such as bees, flies or butte...nts of natural selection on nectar composition. In order to determine whether butterflies actually need nectar amino acids, researchers from the University o...Open microfluidic and nanofluidic systems
...rk towards the construction of "labs-on-a-chip" in order to integrate chemical and biochemical analyzers on...tions include customized chips for space travel in order to monitor microbes inside spacecraft or to detect life on other planets. An obvious prerequisite fo...Singers (and parents) take note: Worst songbird rehearsals precede best debuts
...y" between one and three months after hatching. In order to learn to sing, it's known that young birds must hear an adult song, and through practice, develop their own version of the tune by comparing their vocalizations to a memory template of the song that they "hear in their heads." Interestingly, resea...JCI table of contents March 1, 2005
...eserve University created mice lacking lubricin in order to better study its physiological function. The researchers pinpoint two ways that lubricin protects joints. First, lubricin preserves the cartilage surface by preventing protein deposition and protecting the cells that make cartilage. Second, lub...Purdue proves concept of using nano-materials for drug discovery
... duplicate how cell membranes function on chips in order to test the potential effectiveness of new drugs to treat diseases. Membranes, which surround cells and regulate the movement of molecules into and out of the cells, contain a variety of proteins, some of which are directly responsible for cancer's a...Biological clock may shut down long-term memory at night
...s called transmitter substances," Eskin said. "In order for transmitters to work, once they are released they have got to be cleared away so that others can subsequently act. So, there are not only important mechanisms to release the transmitters, but also mechanisms to get rid of them, and these are cal...California researchers help map human genetic variation across populations
...he high correlations between the different SNPs in order to predict the SNPs that were not sequenced." The HAP study found substantially more blocks in the African American map than in the European American and Han Chinese maps, indicating that the greatest genetic diversity was in samples of African Ame...