Tag: "orders" at biology news

Fusion in the fast lane

...eriments improved the temporal resolution by three orders of magnitude and revealed that the fusion process is surprisingly fast", says Rumiana Dimova, group leader in the Max Planck Institute of Colloids and Interfaces, and one of the participating scientists. Indeed, only a few hundred microseconds afte...

Molecular atlas provides new tool for understanding estrogen-fueled breast cancer

...on (ChIP) to purify the regions of genes that take orders from the ER. They then placed these pieces of DNA on "microarray chips" containing the entire human genome sequence. This allowed the researchers to identify all the points in the genome where binding with the ER takes place. The researchers coined...

IU, Purdue selected for major NCI biomarker tools initiative

...aluation. This proprietary technology adds several orders of magnitude increased dynamic range for cancer biomarker proteomics studies. In Indianapolis, proteomics work will be conducted by the Protein Analysis and Research Center, the academic service component of the Indiana Centers for Applied Protein S...

Road-crossing in chimpanzees: A risky business

...ting, but comparable data on great-ape progression orders have been lacking. Crossing of man-made roads, sometimes necessitated by intersection with longstanding chimpanzee travel routes, presents a new situation that calls for flexibility of responses by chimpanzees to variations in perceived risk. Underst...

Scientists reverse evolution

...trol of the eyeballs.) -- The Hoxb1 gene, which orders the formation of particular nerve cells in rhombomere 4 nerves that ultimately control facial expressions in animals. When a mouse is born with a disabled Hoxb1 gene, it suffers facial paralysis, and is unable to blink its eyes, wiggle its whiskers ...

Ocean microbe census discovers diverse world of rare bacteria

...diversity. "The depth of sampling conducted is orders of magnitude greater than previously available and reveals the enormous range of genetic diversity of different microbes in the ocean," she says. Says co-author Gerhard Herndl of the Netherlands: "Once we catalog the diversity of microbial life i...

New paradigm will help identify leads for drug discovery

...t seven or more concentration levels spanning four orders of magnitude. The multi-concentration screen produces a pharmacological characterization of all the compounds that is far more complete and reliable than traditional methods. "This advance is crucial to NIH's goal of efficiently profiling the range...

How purple corn and RNA break genetic laws

...amutation occurs, one version of the parent's gene orders the other to act differently in the next generatio...tion of the b1 gene and how those cease-and-desist orders are faithfully transmitted to progeny in the absence of changes in the DNA. ...

News tips from the Journal of Neuroscience

...rom the cortex and converge on motor neurons under orders from the superior colliculus via the brainstem and cerebellum. These pathways adapt over a lifetime to maintain accurate saccades. This week, Soetedjo and Fuchs asked where those adaptations occur. The authors trained monkeys to focus on jumping targ...

How plants avoid feeling the burn

...d form. However, the electrical conduction was two orders of magnitude higher when compared to what is needed for the photoprotective effect to work. The group also measured how fast the electrons traveled across the carotenoid bridge between the electrodes. By measuring carotenoids of different chemical l...

New treatment option breaks Leukemia's resistance to chemotherapy, radiation therapy

...herapy increases the dose to leukemia cells by two orders of magnitude and causes cell kill of single-targeted leukemia cells--all while sparing non-target tissues from detrimental radiation effects." With the group's approach, "therapeutic efficiency is increased and non-specific toxicity to normal organs ...

Researchers discover how bacteria sense their environments

...cted, and this sensitivity is maintained over five orders of magnitude in nutrient concentration," said Brian Crane, assistant professor of chemistry and chemical biology and corresponding author of the paper. "Biologically, I know of no other system that is so sensitive over such a large range." Crane bel...

Scientists design potent anthrax toxin inhibitor

...inhibitor binds the toxin at multiple sites and is orders of magnitude more potent than an inhibitor that binds at a single site. The multiple peptides on the functionalized liposome are arranged with the same average spacing as the binding sites of the PA molecule, which permits a firmer bond between the t...

Anthrax inhibitor counteracts toxin, may lead to new therapeutics

...owing it to bind at multiple sites and become four orders of magnitude more potent than an inhibitor that binds to a single site. "Think about how two Lego blocks snap together. A brick with four studs can interlock with a brick with four holes. These bricks will grip together better than if they had only ...

MIT: Oceans are a major gene swap-meet for plankton

...Chisholm said. "We found first that two clades are orders of magnitude more abundant than all of the rest, and that temperature appeared to be very important in determining their distributions." Subsequent laboratory experiments with the cultured strains confirmed this idea. Further analysis showed that mos...

Data published in PNAS show antibodies can be made 10 times more toxic to cancer cells

...ell-mediated Cytotoxicity (ADCC), by more than two orders of magnitude. Studies conducted in in vivo models demonstrated that these antibodies were greater than ten times more toxic to target cells. The enhanced antibodies also were able to kill tumor cells that are typically "invisible" to other antibodie...

Nanoparticles create biocompatible capsules

...That is, the capsules are well behaved, and follow orders without wandering off and propagating." As proof of concept, Granick and Zhang encapsulated fluorescent dyes within lipid capsules. No leakage occurred, and the lipids proved stable against further fusion. "This opens the door to using biologically f...

Story tips from the Department of Energy's Oak Ridge National Laboratory

...h broadens its range of available energies by five orders of magnitude, will enhance the facility's ability to investigate the interactions of atomic and molecular ions with matter. These studies are being performed to explore atomic collision phenomena in a wide variety of plasma environments, ranging from...

U of S researchers develop new vaccine candidate against hepatitis C

...otein in immunized mice using this model were five orders of magnitude lower than the control....

The unfolding of amyloid's true colors

... In fact, rM{alpha} formed amyloids at a rate four orders of magnitude faster than the rate of formation for other well-known amyloids--A{beta} and {alpha}-synuclein, which are implicated in Alzheimer and Parkinson disease, respectively. The authors offer the intriguing hypothesis that by rapidly folding in...

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(Date:10/18/2014)... 2,000 patients referred for evaluation of suspected genetic ... for 25 percent, including detection of a number ... to disease, according to a study appearing in ... to coincide with the American Society of Human ... exons or coding regions of thousands of genes ...
(Date:10/17/2014)... German . Why ... order to reproduce? And why are there two sexes anyway? ... issue of the research journal Molecular Human Reproduction ... from Bielefeld University Bielefeld has compiled this special issue on ... female to copulate with several males in quick succession – ...
(Date:10/16/2014)... constantly wages war on the human body. Battles ... stalemate. In pancreatic cancer, this stalemate—known as tumor ... aggressively malignant, a phenomena that is poorly understood. ... the laboratory of Salvatore Torquato, a Professor of ... conditions surrounding tumor dormancy and the switch to ...
Breaking Biology News(10 mins):Whole-exome sequencing shows potential as diagnostic tool 2Sperm wars 2Modeling tumor dormancy 2
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