Study begins to reveal clues to the cause and progression of sepsis
...matory response to an infection, which can lead to organ failure and death. More than 30 percent will die, making sepsis the 10th leading cause of death. While incidence rates of sepsis have been steadily increasing over the years, little is known about the condition. Past investigational treatments have b...Research shows skeleton to be endocrine organ
...r the first time that the skeleton is an endocrine organ that helps control our sugar metabolism and weight and, as such, is a major determinant of the development of type 2 diabetes. The research, published in the August 10 issue of Cell, demonstrates that bone cells release a hormone called osteocalci...Sugar and spice and everything nice: Health differences in newborn girls and boys
...graft losses. During liver transplantation, the organ undergoes a period of no-flow ischemia, or complete lack of blood flow, and therefore must rely in part on internal nutrient stores to produce energy anaerobically (without oxygen). The end-products of this process (anaerobic metabolism) are lactate ...The 'female advantage' in kidney disease does not extend to diabetic women
... deeply into understanding how sex hormones affect organ function in each gender." ...Disabling a sensory organ prompts female mice to act like male mice
By short-circuiting the sensory organ that detects the chemical cues mice use to attract...mice, at least, are ruled by a pheromone-detecting organ that engages a neural circuit that determines whether a mouse shows its feminine side or acts like a...A sensory organ, not the brain, differentiates male and female behavior in some mammals
...ic behavior in many species may be a small sensory organ found in the noses of all terrestrial vertebrates ...erpretations," Dulac says. "Either the vomeronasal organ may be needed to grow a female-specific neural circuit during development, or the mature female mous...Coelacanth fossil sheds light on fin-to-limb evolution
...s down, hovering just above the sea floor using an organ in their nose to detect living things in the mud. It was astonishing luck that we found it, Friedman said, adding that the fossil had fallen off a cliff a couple of hundred feet high and landed in a different set of rocks. The four-inch long speci...Forsyth scientists gain new understanding of adult stem cell regulation
...a stem cell to specialize and to become part of an organ e.g.: liver or skin. In recent years, planarians... to adult/somatic stem cell behavior in vivo or to organ regeneration. This work demonstrates that gap junction channels providing direct cell-to-cell commu...Cost-effective method for gene silencing is featured in Cold Spring Harbor Protocols
...ent/full/2007/16/pdb.prot4808 ). The thymus is the organ where T-cellsa principal component of the immune s...being released into the bloodstream. Fetal thymus organ culture is the only system available for studying the complete program of T-cell maturation in vitro...UF to lead research on life-threatening fungus
...ell as among those who receive certain other solid organ transplants, he said. About 15 percent of all bone marrow transplantpatients, for example, will develop an infection from Aspergillus; of those, about two-thirds die. "We haven't had good treatments, we haven't had good prevention methods and, most...Rare example of Darwinism seen in action
...nflict over nutrients. The placenta is a complex organ of maternal and fetal tissues that nourishes the developing fetus in the uterus. Most mammals, excluding marsupials like the kangaroo and the koala, have a placenta. Because of the placenta, a developing embryo remains longer inside the mother (in...After a decades-long search, scientists identify new genetic risk factors for multiple sclerosis
...ocks IL2R-alpha, developed to prevent rejection of organ transplants. Finally, the genome-wide scan identified nearly a dozen other genes that could represent risk factors for MS. Some of the associations were relatively weak and some of the genes' functions are unclear. "A major effort to understand ...Gene expression pattern could lead to improved treatment of pediatric septic shock
...n to inhibit septic shocks progression to multiple organ failure. Zinc was not even on our radar screen for this disease process, said Dr. Hector Wong, M.D., professor of Pediatrics and director of Critical Care Medicine at Cincinnati Childrens. This study demonstrates the potential power of genomic med...Immune system 'escape hatch' gives cancer cells traction
...esponse to stress, bacterial and viral infections, organ transplantation and autoimmune diseases. Their goal, researchers say, is to find some means of accelerating or slowing down T-cell activity gone awry....Kaposi sarcoma arises independently from multiple cells
... be more invasive leading at times to catastrophic organ dysfunction and even death. It is also not known if the clonal [Kaposi sarcoma] lesions identified in this study were more aggressive and less likely to respond to therapy, Gill writes....Study finds Western-style 'meat-sweet' diet increases risk of breast cancer in postmenopausal women
...by various meats, primarily pork but also poultry, organ meats, beef and lamb, and shrimp, saltwater fish, and shellfish, as well as candy, dessert, bread, and milk. The vegetable-soy pattern is associated with various vegetables, soy-based products, and freshwater fish. Of 1,602 breast cancer cases ide...Insulin sensitizer also serves as energy-conserving signal to the brain
...d. It is also recognized as an important endocrine organ that secretes a number of biologically active signaling proteins, called adipokines. Adiponectin, an adipokine secreted exclusively by WAT, is present at relatively high concentrations in the circulation and has been shown to increase the bodys respo...A gene that protects from kidney disease
...g childhood that leads to kidney failure requiring organ transplantation. The insights might help develop e... being that large numbers of kidney cells die. The organ shrinks and changes in its architecture occur which affect normal kidney function. To find out if ...Variant CJD -- Prion amplification breakthrough brings new insights and hopes for a blood test
...is disease on to others through blood transfusion, organ donation or surgery.......ve mesenchymal stem cells see a tumor as a damaged organ and migrate to it, and so might be utilized as a vehicle for treatment that can find both primary tumors and small metastases. These stem cells also have some plasticity, which means they can be converted by the micro environment of a given tissue in...