Tag: "osteoarthritis" at biology news

UD awarded $11M for osteoarthritis research and unique mentoring program for women scientists

...Health for leading-edge, translational research on osteoarthritis that includes a unique mentoring program to foster...really unique is a collection of people to address osteoarthritis across multiple levels, which is what translational medicine is all about, Buchanan said. We have ...

Why small dogs are small

...n size and shape, and in their tendency to develop osteoarthritis and Addisons disease, a hormone disorder suffered by assassinated U.S. President John F. Kennedy. "There are at least 1,000 Portuguese water dog owners throughout the country who are very proud of the fact their breed has led the way," Lark says. ...

Cartilage discovery offers arthritis hope

...l provide clues to how the crippling joint disease osteoarthritis might one day be treated. The disease, which affe...facts that could prove useful in future studies on osteoarthritis and related conditions." The next stage of the team's work will be to determine the structure of th...

Pittsburgh-based team engineers muscle, bone cell differentiation with aid of ink-jet printer

...interface. Patients afflicted with conditions like osteoarthritis might benefit from these therapies, which incorporate the needs of multiple tissues and may improve post-treatment clinical outcomes. The long-term promise of this new technology could be the tailoring of tissue-engineered regenerative therapies. In...

How movement lubricates bone joints

...n a type of childhood joint failure that resembles osteoarthritis in the elderly. Sahs goal is to stimulate healthy chondrocytes in cartilage tissue grown in the laboratory to form robust tissue that makes proteoglycan 4 and has a smooth, well-lubricated surface....

Rock climbing does not increase risk of osteoarthritis

...dy in the US has found there is no greater risk of osteoarthritis in rock climbers compared to non climbers, contrar...ticipant and were scored for radiographic signs of osteoarthritis using an atlas method. We compared 27 recreational rock climbers and 35 non-climbers for four measur...

Gene therapy research switches off joint inflammation; switches on genetic process of joint repair

...d functional assessments in subjects with moderate osteoarthritis of the knee. Prior to this clinical investigation Reparagen was found to be the first natural product to "silence" genes that promote joint damage while simultaneously activating the repair gene, IGF-1, in human chondrocytes.2 The clinical study bein...

New genes implicated in rheumatoid arthritis

...ene expression in synovial tissue of patients with osteoarthritis (OA). Between the disease-discordant twins, minor yet measurable differences were detected in the expression of 1,163 transcripts, representing 827 uniquely named...

Tufts researchers are keeping track of vitamin K: Research summary

...s possible links to a number of conditions such as osteoarthritis and coronary heart disease. "We know that meats, d...f phylloquinone were associated with lower risk of osteoarthritis in the hand and knee. Of the other forms of vitamin K, Booth says, "We are just beginning to study t...

Penn researchers discover gene that creates second skeleton

...sports injuries, blast injuries from war, and even osteoarthritis and damaged heart valves. Perhaps someday we will be able to harness the gene mutation that causes the renegade bone formation in FOP and make bone in a controlled way for patients who have severe osteoporosis, for those with severe bone loss from t...

Obese people are more sensitive to pain, suggests study

...ll of the older adults who completed the study had osteoarthritis of the knee, a disease that causes inflammation an...ssive relaxation techniques would help people with osteoarthritis to better cope with the pain that the disease can cause. Also called degenerative joint disease, ost...

Bone quality regulator identified, suggests drug target

...f bone to either prevent the damage that occurs in osteoarthritis and osteoporosis, or improve the quality and speed of bone repair following bone fracture, joint implantation, dental implants or bone grafting. Aging baby boomers This strategy could prove particularly useful for aging baby boomers, as joint-repla...

Scholar uncovers the story behind the 'obesity epidemic'

...vincingly to be caused by excess body fat, such as osteoarthritis of weight bearing joints and uterine cancer that comes from higher estrogen levels in heavier women, although this can be treated medically without weight loss," he said. "For most medical conditions, it is diet, exercise, and genetics that are the r...

Study links low selenium levels with higher risk of osteoarthritis

...a continuing, federally supported investigation of osteoarthritis that began 15 years ago and is headquartered at UN... suggest that we might be able to prevent or delay osteoarthritis of the knees and possibly other joints in some people if they are not getting enough selenium. That'...

Scientists launch new study into canine arthritis

The study will help vets understand how osteoarthritis progresses in dogs and how treatment may slow the disease down. To take part in the study Labradors must be less than two years old and show early signs of elbow osteoarthritis. A mobile Magnetic Resonance Imaging (MRI) scanner will make regular visi...

The (cell) matrix reloaded

...sion plays in regulating tumour spread, while with osteoarthritis we are looking to replace damaged cartilage. "The research where we're closest to clinical trials, perhaps as soon as next year, is vascular engineering where we want to replace vessels affected by vascular disease." The Centre, which is based in the...

Arthritis: What Wnt wrong?

...al knee replacement for rheumatoid arthritis (RA), osteoarthritis (OA), or non-arthritic injury. Using several molecular methods, Wakitani's group identified Wnt-7b and -10a as genes that were significantly upregulated in the arthritic knee tissues. However, protein expression studies revealed that only Wnt-7b w...

Results of world's first gene therapy trial for arthritis show approach safe, feasible

...hope to conduct additional clinical trials in both osteoarthritis and rheumatoid arthritis using AAV to transport the gene. In addition to Drs. Evans and Robbins, other authors are James H. Herndon, M.D., also now at Harvard; Steven C. Ghivizzani, Ph.D., now at the University of Florida; Mary Chester Wasko, M.D., M...

Liverpool vet creates pain relief diet for arthritic dogs

...w food for dogs to help relieve the pain of canine osteoarthritis (OA). Professor John Innes, from the University's Department of Veterinary Clinical Science, has been working with colleagues at the University of Cardiff to create the specialist diet that can alleviate the discomfort caused by the condition, as we...

Inflammatory condition doubles heart attack, stroke risk

... GCA to two control groups without GCA those with osteoarthritis and those without any arthritic condition. When compared to the former, the risk of cardiovascular disease among GCA patients was 1.6 times higher. Compared to the healthy adults, however, GCA patients had more than a doubling of their risk of cardio...

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