Female gender provides an advantage in renal diseases
...rently analyzing data from a clinical study of the osteoporosis prevention drug, raloxifene. As raloxifene has estrogen-like properties, the researchers hypothesized that raloxifene may affect the progression of renal disease in these women. Broad-based preliminary data from this study will be presented at the ...Gum disease in postmenopausal women linked to oral bone loss
...population-based investigation of risk factors for osteoporosis and oral bone loss in postmenopausal women, which is an offshoot of the observational portion of the national Womens Health Initiative (WHI). Participants in this study completed questionnaires, had physical measurements taken, had bone-density test...Women up to age 30 at risk for bone loss, study finds
... bodys ability to form new bone, which can lead to osteoporosis later in life. Researchers recommend that the more women exercise, the more they need to eat to stay healthy. Thousands of women severely restrict their diet and practice rigorous exercise programs for fitness and weight control, said Anne Loucks,...FSU engineering professor growing bone in a lab
...fective for correcting bone defects resulting from osteoporosis and other bone-related diseases. One out of every two women and one in four men over the age of 50 eventually will suffer an osteoporosis-related fracture, and many more are at risk. Such fractures typically occur in the hip, spine and wrist. "Curr...IMS updated recommendations on postmenopausal hormone therapy
...ity and overall quality of life. Postmenopausal osteoporosis HT is effective in preventing the bone loss associated with the menopause and decreases the incidence of all osteoporosis-related fractures, including vertebral and hip, even in patients at low risk. Although the magnitude of decline in bone turnove...Scientists identify a candidate gene for osteoporosis
...According to the National Osteoporosis Foundation, osteoporosis affects 55% of Americans over the age of 50. Low ...hromosomal region has also been shown to influence osteoporosis in humans. The protein encoded by DARC binds to chemokinesor small signaling proteinsthat are ...Rare mutation causes early heart disease and metabolic syndrome
...nteresting given recent evidence of association of osteoporosis with CAD. By comparing the inheritance of CAD to the inheritance of each chromosome segment in the pedigree, the team narrowed the location of the disease-causing gene to a short segment of chromosome 12. In this region, they found a single mutation...Single genetic defect causes early heart disease
.... The discovery that the LRP6 mutation also causes osteoporosis raises the possibility of a linkage with coronary ..., said Lifton. "There is emerging recognition that osteoporosis and coronary artery disease occur together more often than expected by chance," he said. "We have no...Experimental Biology 2007: Today's Research, Tomorrow's Health, April 28-May 2
...betes, cancer, cognitive decline, chronic disease, osteoporosis and other diseases; obesity-associated inflammatio...lications; nanotechnology in disease therapeutics; osteoporosis and bone research (a symposium subtitled "no time to be bad to the bone"); toxicology of nanomateria...Researchers urge monitoring of bone health during chemotherapy
...ngthening the skeleton would not only help prevent osteoporosis and fractures but also might give patients a survival advantage." In the laboratory mice studied, G-CSF increased the number and activity of bone cells called osteoclasts, which resorb bone material as part of the normal process of bone turnover. The...Proposed FDA claim recognizes role of key nutrients in dairy in reducing osteoporosis risk
...in D and the role it plays in reducing the risk of osteoporosis will draw attention to milk as one of the richest ... and providing the best defense against developing osteoporosis later in life," says Frank Greer, MD, FAAP (Fellow of the American Academy of Pediatrics), chairman ...High levels of vitamin D in the body may decrease the risk of multiple sclerosis
...er vitamin D levels could be beneficial to prevent osteoporosis and other chronic diseases." The researchers note that there could be other possible explanations for the protective role of vitamin D. For example, its possible that exposure to UV light from the sun--the major determinant of serum levels of 25-h...'Best of both worlds' -- Targeting a single gene could inhibit bone decay and stimulate bone growth
...tion. This concept may lead to drug treatments for osteoporosis and other bone diseases. Senior author Yongwon Cho...gely understood, hence a handful of drugs treating osteoporosis are available. Most drugs inhibit osteoclasts, which cause bone decay. But there is also at least on...Turmeric prevents experimental rheumatoid arthritis, bone loss, University of Arizona study shows
... resorption. Noting that bone loss associated with osteoporosis in women typically begins before the onset of menopause, she has begun work on another NIH-funded study to determine whether turmeric taken as a dietary supplement during perimenopause can prevent bone loss and osteoporosis. Both of the studies are s...Researchers discover new gene responsible for brittle bone disease
... found that, without this key gene, mice developed osteoporosis due to defects in their osteoblasts. Another team working at McGill University in Montreal identified human patients who had OI due to mutations in CRTAP, demonstrating for the first time that CRTAP has an essential function in humans. In addition...JCI table of contents: October 19, 2006
... BONE BIOLOGY: Hyperactive osteoclasts cause osteoporosis in neurofibromatosis type 1 patients Neurofibromatosis type 1 (NF1) is a relatively common genetic disorder (around 1 per 3,000 births) caused by inheriting one mutated copy of the gene NF1. Individuals with NF1 exhibit a range of symptoms, the mo...Genetic mutation explains form of brittle bone disease
...cher," said Lee. "We had produced a mouse model of osteoporosis stemming from clear and novel biochemical activity associated with the mutant CRTAP protein. And we had shown that there is an effect on the collagen fibers. And now we had shown that there is a clinical spectrum of brittle bone disease associate...Forsyth scientists find linkages between serotonin reuptake inhibitors and bone mass
... help us learn more about the underlying causes of osteoporosis and gain a new understanding of bone formation at a molecular level," said Dr. Battaglino. "Furthermore, this research provides exciting clues on how to prevent destructive bone loss and even improve bone mass in certain medical/dental conditions."...Convening kidney health in Copenhagen
...y, receptors and cellular mechanism of regulation, osteoporosis and renal osteodystrophy, and phosphatonins. Specially crafted to close the bench-to-bedside loop, the four translational sessions are uniquely designed to attract both research scientists and physicians in order to signpost future directions and o......nes," says Tucker. "However, women concerned about osteoporosis may want to steer away from frequent consumption of cola until further studies are conducted."...