Molecular technique shows promise in destroying drug resistance in bacteria
...mselves impervious, such as by pumping antibiotics out of the cell, preventing them from entering the cell or demolishing them. A common way bacteria develop resistance is by laterally transferring plasmids -- pieces of extra-chromosomal DNA -- from one bacterium to another. These plasmids contain gene...Tropical birds sensitive to environmental cues that can be impacted by global warming
...tial mates -- and a warning to other males to stay out of his territory. To Ignacio Moore, assistant prof... songs were a curiosity that made him want to find out why birds sang at some times and not at others, at some places and not elsewhere. Moore and Universi...Illegal tuna fishing and farming leads to demise of species
...w how the fast-growing tuna farming businesses are out of control," said Paolo Guglielmi, head of WWF Med...llocated to ICCAT delegations' fishing industries, out of their overall catch quotas on the East Atlantic bluefin tuna stock....Ancient fossil offers new clues to brown bears past
...enter, came across a brown bear fossil that seemed out of place. The fossil had been collected by Jim Burns, curator of Quaternary mammals at the PMA a few years earlier near Edmonton, Alberta, in gravels that date to before the last ice age (older than 24,000 years). If this was true, Matheus thought, i...NIEHS to develop new RNAi library to help fight disease
...hways," Olden added. "We're very pleased to carry out this important work that will benefit the entire s...na-based biotechnology company, Icoria, will carry out the three-year contract, which is the first phase of the NIEHS RNAi initiative. Part of the Nationa...Lyme disease receptor identified in tick guts
...hen we used RNA interference to knock the receptor out of the ticks, they no longer carried Borellia burgforferi," said Fikrig. "We are excited to learn more about the life cycle of this important pathogen," Fikrig added. "This information can also be used to study other vector-borne diseases such as We...Academy eBriefings offer comprehensive reports on more than 100 cutting-edge scientific issues
...thousands of people around the world eager to find out the latest news and research on topics such as diabetes, AIDS, cholesterol and obesity, vitamin E and aging, hunger in Africa, hydrogen-powered vehicles, and other cutting-edge science and social issues. Sponsored by the Academy, one of the U.S.'s o...Scientists advocate genomic sequencing of 'living fossil'
...former graduate student on Myers' team who carried out much of the work described in the Genome Research article, focused on a small but highly informative genomic segment from the Indonesian coelacanth (Latimeria menadoensis) called the protocadherin gene cluster. Encoding for proteins involved in the ...New tool highlights activity of key cellular signal
...messages, scientists have had a hard time figuring out how it can trigger the right cellular response to each one. "Scientists suspected that timing and location of cyclic AMP activity was important, but there was no easy way to study cyclic AMP inside cells in real time and in real space," says Jin Z...Sex versus survival: A tradeoff at geographical range limits
...ost trait, is our tailbone. "If our data are borne out by other genetic studies, it means that these complex traits can be eroded very quickly."...UCSD discovery opens new avenues for design of anti-tumor medications
...sels-- have focused on inhibiting the signals sent out by the tumor in response to low oxygen. These lat...is inhibitors. Furthermore, the researchers point out that it may be easier to design effective treatments that target the endothelial cells rather than t...Nuclear imaging offers possibility for early detection of patients with coronary heart disease
... and Metabolic Imaging of Atherosclerosis" pointed out that, "recent advances in understanding of the pathobiology of atherosclerosis have highlighted the inadequacies" of imaging the disease with X-ray angiography. John R. Davies, B.Sc.; James H. Rudd, Ph.D.; and Peter L. Weissberg, M.D., stated the nee......own to be involved in shuttling materials into and out of cells but was not previously associated with HIV. The authors show that HIV infection could be prevented by directly blocking annexin 2 or by eliminating it from the cell surface. Although they do not know exactly how annexin 2 helps HIV get into...November nutrition news from the Friedman School of Nutrition Science and Policy at Tufts
...tack ubiquitin and other proteins in the eye, wipe out the benefit-giving ubiquitin pathway. Free radicals are thought to be a fundamental cause of many degenerative diseases and the aging process and can be produced naturally in the body over time, or they can be caused by environmental factors--such as...New protein identified in development of lung cancer
...ble new target for intervention. Villalona points out that new drugs are already on the market that can inhibit the activity of the proteasome, and suggests that these drugs may be able to counter Pirh2's oncogenic behavior by restoring p53 function. Additional studies would be needed to demonstrate tha...Army-funded effort examines androgen's role in bone loss
...ich androgen influences the skeleton. "It turns out that one of the most common injuries sustained in ... a common treatment for prostate cancer that wipes out most male hormones found in the body. "Women and estrogen have been targets for a lot of osteo...Seeking better cancer treatments
...ASTEREC and its follow-up E! 2705 SAMARDES carried out essential research with the human androgen receptor to understand the mechanism of the mode of action of androgens. The human androgen receptor (hAR) binds the male sex steroids and regulates genes for male differentiation and development. The leng...IRCM scientist demonstrates basic active mechanism of immune-system cells
...g issue of Immunity, a highly regarded journal put out by the Cell group, Dr. Andr Veillette, a scientist at the Institut de recherches cliniques de Montral (IRCM), and his team will publish the results of a study that could revolutionize the treatment of autoimmune diseases, such as juvenile diabetes, l...A $2 Million NSF grant brings technology and biology together at UC Riverside
...gement practices to keep nitrates from fertilizers out of the ground water supply, and to reduce concentr...er data on habitat microclimates and computers map out the potential damage from wildfires. This program will be shown at other dates and times during the ...Genome of ancient fish could reveal evolutionary mysteries, Stanford scientists say
...ound fish in question, called the coelacanth, ekes out an existence in cool, deep-water caves off the Comoro Islands in the Indian Ocean and northern Indonesia. Its lobed fins, skeleton structure and large, round scales are practically unchanged from its fossilized ancestors. This resemblance is what mak...