Tag: "ovarian" at biology news

Support groups aid women with 'breast cancer gene mutations'

...have up to a 90 percent lifetime risk of breast or ovarian cancers. As a result, they must address difficult issues that can lead to depression and anxiety, including the perception of personal vulnerability to cancer, and communicating the inheritable vulnerability and its risks to their family. Moreover, t...

Medical informatics project targets ovarian, breast cancers

... better understand the damage caused by breast and ovarian cancers. Funded by the National Cancer Institute, ...believe our work will lead to better therapies for ovarian and breast cancer patients." The researchers will study the genetic and molecular consequences of DN...

Moffitt doctor's talk on ovarian cancer receives international first place award

...vidualize therapy for patients with advanced stage ovarian cancers. Lancaster sought to develop gene expression profiles that predict response to platinum-based chemotherapy using microarray expression analysis. Data obtained from cancers of patients who demonstrated a complete response to platinum-based t...

New Italian research links migraine and endometriosis

...ere undergoing laparoscopy because of infertility, ovarian cysts, benign uterine tumours or pelvic pain. All the women who indicated that they had had at least one headache in the past year were referred to a specialist headache neurologist who performed a clinical interview and classified their headaches ac...

Study links polycystic ovary syndrome with early vascular changes of heart disease

...ity, irregular menstrual cycles, excess body hair, ovarian cysts, acne and obesity. The American Association of Clinical Endocrinologists issued a position paper just weeks ago to raise awareness of the disorder, saying that women with PCOS "are at greatest risk for diabetes and coronary artery disease." ...

World's largest population study on BRCA1/2

...CA2 mutation testing has confirmed that breast and ovarian cancers are the major concerns for geneticists and...ne woman with breast cancer and another woman with ovarian cancer, most ovarian cancers are not attributable to BRCA1/2 mutations. Other, as yet unknown, non-B...

Other highlights in the November 17 JNCI

...etaxel and carboplatin for first-line treatment of ovarian cancer appears to result in similar rates of survi...s considered the standard of care for treatment of ovarian cancer. However, another taxane, docetaxel, has shown superiority over paclitaxel in the treatment o...

Researchers call for studies on role of BRCA1 mutations in chemotherapy response

... BRCA1 mutations account for only 5% of breast and ovarian cancers, but loss-of-function mutations in the BRC... 82% risk of breast cancer and up to a 54% risk of ovarian cancer. Because BRCA1 is involved in DNA repair, loss of a functioning BRCA1 gene may make a cell mo...

Gene expression profiling aids in ovarian cancer prognosis

...mine the prognosis of patients with advanced stage ovarian cancer and may eventually help provide targeted th...ic test has proven useful as a prognostic tool for ovarian cancer, which accounts for approximately 26,000 new cases and 16,000 deaths in the United States eac...

Yale and Pfizer launch visiting professorship pilot program

...aboratory are particularly advanced for breast and ovarian cancer patients, but also show promise for prostate, pancreatic and lung, as well as in certain brain tumor patients. ...

Cloned gene from sea animal may prove key in cancer drug development

...phoma and several cancers including colon, breast, ovarian and prostate. One of the main obstacles impeding widespread bryostatin production is lackof a practical and economically viable method of producing the compounds.The bacteria cannot be grown in laboratories. And collecting vast numbers of the animals...

False positive screening for cancer found to be frequent and costly

...ss of screening for prostate, lung, colorectal and ovarian cancers. "The results of this smaller study add to the growing body of evidence highlighting the importance of understanding not only the likely benefits of cancer screening, but also how the accuracy of screening tests impacts patients and medical...

JCI table of contents, December 15 2004

...roles of platelets in the metastasis of breast and ovarian cancer cells to the bone. They show that platelets act as: (i) a direct source of lysophosphatidic acid (LPA), which promotes tumor cell division; and (ii) indirect activators of bone breakdown. The authors demonstrate in mice that tumor cells encour...

Other highlights in the January 5 JNCI

...ignaling, are associated with an increased risk of ovarian cancer, according to a new study. The PROGINS alle...gene has been associated with an increased risk of ovarian cancer and a decreased risk of breast cancer. To refine the association between common variations in...

Research may speed development of new oral drugs for fertility treatments

... to its receptor then stimulates the maturation of ovarian follicles in women or sperm production in men. Insights gleaned from this structure could aid in the development of improved fertility drugs or contraceptives for both men and women. Hendrickson and Fan, who are both at Columbia University, reported ...

Increased risk of osteoporosis associated with gene that one in five people have

...inked to estrogen-related cancers, such as breast, ovarian or endometrial cancers," says Reina Armamento-Villareal, M.D., assistant professor of medicine in the Division of Bone and Mineral Diseases. "The link to estrogen suggested that the gene could also affect bone density. No one had ever investigated th...

MRI 'excellent choice' for overcoming challenges of diagnosing pregnant women with abdominal pain

...gnosis was made, the one exception being a case of ovarian torsion (twisting of the ovary), which was correct...ain were diagnosed on MRI, including appendicitis, ovarian cysts, hemorrhage and pancreatitis. According to the researchers, diagnosing acute abdominal pain in...

Other highlights in the February 16 JNCI

...patterns in a blood sample could be used to detect ovarian cancer. However, questions have been raised about ...ew York, Stony Brook, that used publicly available ovarian cancer datasets produced by Lance A. Liotta, M.D., Ph.D., of the National Cancer Institute, and Eman...

Anti cancer virotherapy well tolerated in first human administration, research finds

... hard to treat malignancies including melanoma and ovarian cancer. These viruses occur naturally and routinel...EV1), which has shown promise in animal studies in ovarian cancer. Professor Shafren's research has shown EV1 to be successful in attacking aggressive ovarian ...

NIH holds conference to assess evidence on management of menopauserelated symptoms

... reported by middle-aged women are attributable to ovarian aging? When do the menopausal symptoms appear, how long do they persist, with what frequency and severity, and what is known about the factors that influence them? What is the evidence for the benefits and harms of commonly used interventions for r...

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