Tag: "ovaries" at biology news
Interaction between stem cells and their niches key to differentiation
...an Lin, Ph.D. studied germline stem cells from the ovaries
of the common fruit fly Drosophila. They analyzed the expression of specific genes as the germline stem cells either created additional copies of themselves or differentiated into another cell type known as a cystoblast, which eventually become matur...
A gene's fist 'kiss' sets off that affair known as puberty
...e rising levels of LH and FSH cause the testes and ovaries
to produce the sex hormones testosterone and estradiol, the culprits responsible for the physical changes and emotional baggage of male and female puberty, respectively. "We now have very good evidence that the GPR54 gene and its switch, the kisspep...
Familiar blood pressure drug may prevent osteoporosis
... destroy less bone and do not lose bone when their ovaries
are removed. This is the first demonstration that nerve cells are involved in osteoporosis development. This has tremendous clinical implications especially since these mice are not obese." Drugs that inhibit the sympathetic nervous system are alrea...
Signaling protein builds bigger, better bones in mice
...on cause of bone loss. When U-M scientists removed ovaries
from normal mice in the study, they developed redu...the Wnt10b females showed no bone loss after their ovaries
were removed. "Because the transgenic mice have more trabecular bone, or bone within the marrow cavi...
Compound inhibits one critical pathway in breast cancer growth
... lung, prostate, head and neck, skin, pancreas and ovaries
as well as lymphoma and certain kinds of leukemia. Stat3 is constantly activated in about 60 percent of breast tumors, said Jiayuh Lin, the study's lead author and an associate professor of pediatrics at Ohio State University. All cells contain Stat3...
What are little boys made of?
...eir normal development and females are not because ovaries
don't fully develop until puberty. This newly described role for ER could be important in research on behavioral differences between men and women, Rissman said, such as in the areas of aggression, nurturing, and cognition. The discove...
First frozen egg baby born in Canada
... the MUHC and Dr. Tan. Each egg extracted from the ovaries
of the patient is drawn into a protective device, invented by Drs. Chian and Tan, called a "Cryoleaf", and then placed in a special vitrification solution. The eggs undergo super-rapid cooling at a rate of more than 20,000C per minute, which prevents...
Discovery suggests why stem cells run through stop signs
...etically modified stem cells from the fruit flies' ovaries
and studied how many egg chambers the mutant stem cells produced as compared to normal stem cells. The production rate in the mutant cells fell over the course of 12 days, and the researchers concluded it was because the mutant stem cells were no lon...
Bone marrow may be source of new egg-cell generation in adult mammals
...g over the next 12 to 24 hours. Two months later, ovaries
from the treated mice looked identical to those fr...study had identified cells on the surface of mouse ovaries
that resembled immature germ cells, which are the source of the oocytes that develop in embryonic an...
Stem cells in bone marrow replenish mouse ovaries
...team reporting the first preliminary evidence that ovaries
of mice can be renewed with new eggs in adulthood....d cell transplants appear to completely revive the ovaries
of female mice sterilized by chemotherapy. Just 24 hours after a transplant, the sterilized mice had...
Formula against infertility
...ne marrow." When needed, they would migrate to the ovaries
and differentiate into new egg cells. This result could also become of great clinical importance one day, perhaps for treating infertility in women after cancer treatment. Experiments with nervous system stem cells are already one step closer to clin...
Israeli scientists successfully transplant frozen-thawed ovaries in sheep
... successfully transplanted whole frozen and thawed ovaries
in sheep, retrieved oocytes from these ovaries
and triggered them in the laboratory into early embryonic development. Follow-up tests showed that t...
Nine minority physiology grad students each get $18,000 Porter Fellowship from APS
...ainst loss associated with gonadectomy (removal of ovaries
or testicles). Currently, she is determining which genes are turned on and off in response to Inhibin both early and later in the bone formation process. This work may provide new targets of Inhibin action to increase bone mass and prevent the bone ...
New weapon in battle against osteoporosis
...is has been supported by experiments on mice whose ovaries
were removed. The resulting oestrogen deficiency would normally lead to a depletion of bone material and finally to "mouse osteoporosis". "We treated these mice with an active substance that bonds specifically to the CB2 receptor. In this way we were...
ASU researchers find link between social behavior, maternal traits in bees
...en is removed, some of these females develop their ovaries
and lay eggs." Foraging for pollen is a maternal r...igh pollen-hoarders would win the race and develop ovaries
sooner than the low pollen-hoarders. Amdam's prediction proved to be correct when after 10 to 21 day...
Component in soy products causes reproductive problems in laboratory mice
...f soy, was found to disrupt the development of the ovaries
in newborn female mice that were given the product...dy looks at the direct effects of genistein on the ovaries
during early development. "We knew genistein was linked to reproductive problems later in life, but ...
Inflammatory reaction drives hormone resistance in cancer, study suggests
...lls precedes every major reproductive event in the ovaries
and uterus, from ovulation to implantation [of a fertilized egg] and menstruation," wrote Malcolm Parker of Imperial College London in a preview. The current study suggests that infiltrating macrophage cells may provide signals for "local expression ...
A surprising pair of proteins help make healthy eggs
...n parallel, Brown scientists studied the defective ovaries
of TAF4b-deficient mice. What they found in mice was similar to what the Berkeley team found in cultured cells: When the level of TAF4b protein decreased, granulosa cells withered, broke apart and failed to multiply. A similar process may be at work ...
US commercial genetic testing does not detect all cancer-associated mutations in certain genes
...tection methods, and prophylactic surgeries of the ovaries
or breast. Because prophylactic surgeries, while highly effective in reducing risk, are also highly invasive, it is particularly important to distinguish mutation carriers from noncarriers with similarly severe family histories. Women with BRCA1 or B...
Pituitary hormone implicated in bone loss after menopause
...vere loss of ovarian function. In mice with normal ovaries
and approximately half the normal concentration of FSH, bone mass increased due to a decline in bone resorption by cells known as osteoclasts, which break down bone. Indeed, they report, FSH stimulates receptors found on the surface of bone-degrading...
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