NIH awards new $14.5 million, five-year grant to the Scripps Research Institute
...that present technological challenges that must be overcome before they yield to high-throughput methods. Thes...res has been successful only where scientists have overcome the technical challenge of producing and purifying the membranes. The Trouble with Membrane Prote...DNA sequence controls expression of gene involved in cancer
...ready used in chemotherapy to induce apoptosis and overcome drug resistance in cancer cells....US researchers show cottonseed drug is cancer treatment booster
...ake radiotherapy andchemotherapy more powerful and overcome the resistance to drug and radiation treatment caused by high levels of Bcl-2/xL. Gossypol was researched as a male contraceptive in China as long ago as 1929 although the results were not published until 1957, but after large scale studies in the 19...New biosensor rapidly detects deadly foodborne pathogen
... York, when the recall was issued. "To overcome the time delay and allow for rapid detection before foods are shipped, you need to be able to detect a lower number of the pathogen cells at the processing plant," Geng said. The ability to detect L. monocytogenes at low levels is esse...Is Interleukin-6 the 'holy grail' of exercise mediation?
...insulin resistant skeletal muscle in an attempt to overcome the impaired glucose uptake. And in other contexts, the current thinking is that IL-6 has primarily anti-inflammatory effects. It is this combination of effects that has prompted such widespread study....University of Edinburgh hosts European conference on childhood disability
...r children with disability and discuss how best to overcome the barriers they face in areas such as learning and mobility. Delegates to the European Academy of Childhood Disability conference, hosted by the University of Edinburgh, will explore the theme of 'From Evidence to Empowerment', debating the whole s...Toward a better understanding of taste and smell impairments
... form the foundation of new approaches to avoid or overcome the sometimes debilitating effects of chemosensory dysfunction. Approximately six million Americans suffer from sensory loss or alteration related to the senses of taste, smell, or both. Although changes in taste and smell perception can signifi...Taking the next step toward growing our own fuel
...on processes for over 20 years. He is striving to overcome the obstacles related to biomass conversion into value-added products. "The beneficiaries of this research will be agriculture and agriculture-based industries in Illinois," Blaschek said, "but ultimately all of us will benefit as consumers of ene...Cooperation to create a new tuberculosis vaccine
...g BCG and the new DNA vaccine has the potential to overcome this hurdle. DNA vaccines deliver genetic information directly into the cells of the vaccinated person, which enables the cells to produce the most appropriate and efficacious vaccine via the safest possible application method. DNA vaccines induce a ...Study using robotic microscope shows how mutant Huntington's protein affects neurons
..."Much was happening that we couldn't see." To overcome this problem, Dr. Finkbeiner and his colleagues wrote a computer program that allows a microscope to match images in a culture dish to images it has stored and to manipulate its controls to look at the same neurons over and over again - like time-lap...Laboratory test of evolutionary theory confirms importance of links between populations
...mmunities, resistant bacteria--and viruses able to overcome that resistance--evolved more rapidly in the chemostats with high nutrient levels than in those with low nutrients. That's because the microbes multiplied more rapidly in the high-nutrient environment, resulting in more opportunities for favorable mu...Plastic surgeons perform first entire face reconstruction
...ocedure is an important step to help burn patients overcome their trauma. As plastic surgeons, we will continue to refine this combination of techniques to help our patients not only rebuild their bodies but also their lives." ...OHSU study: Bacterial switching mechanism key to survival
...ed for the human body to mount a counter-attack to overcome a bacterial infection."...Retinal stem cells can regenerate after transplant
...es. "We're starting with mice to see if they can overcome the genetics involved in disease," says Coles. "The eye itself is telling the stem cells what to do, so when we go to a disease model, it is important to know what those signals from the eye are so we can inhibit them or protect the cells." The other...A clear view of mycobacterial infection
...occurs deep in the lung of the infected animal. To overcome this limitation, Ramakrishnan and colleagues used zebrafish embryos, which are transparent and can be infected by a relative of the TB pathogen, M. marinum. This enables the researchers to watch cells as they are recruited into the granuloma. By vis...Tufts Veterinary School scientists decode Cryptosporidium genome
...nausea, and vomiting. While healthy people usually overcome illnesses caused by the organism, it can be life threatening to malnourished children and people whose immune systems have been compromised because of cancer, AIDS, etc. The Cryptosporidium pathogen, which can be found in the feces of both humans...Red wine mist? Resveratrol shows potential effects against COPD, asthma, arthritis
...etter option," Donnelly said, noting that it would overcome one of the problems with steroids, which is noncompliance. The current research aimed to confirm and quantify the effect of resveratrol and quercetin, a related plant-derived polyphenolic compound that often mimics its diverse activities, and to furt...Research to explore revolutionary gene sequencing: Threading the molecular needle
...of significant technical hurdles still need to be overcome before the idea can be considered a usable technology. With the goal of overcoming these technical challenges, the National Human Genome Research Institute (NHGRI) of the National Institutes of Health has awarded a $550,000 three-year grant t...Researchers grow sperm stem cells in laboratory cultures
...am of researchers working with cells from mice has overcome a technical barrier and succeeded in growing sperm progenitor cells in laboratory culture. The researchers transplanted the cells into infertile mice, which were then able to produce sperm and father offspring that were genetically related to the do...Researchers uncover how infections combat plant immune responses
...oduce more than one suppressor of RNA silencing to overcome the antiviral immunity," he added. "Secondly, one of the CTV suppressors identified is mechanistically novel as it inhibits spread of RNA silencing without interfering with intracellular RNA silencing." As a result, that type of suppressor cannot be...