Tag: "overdrive" at biology news
Grants put ANU in bird flu fight frontline
... especially avian flu, the immune system goes into overdrive
and creates what is know as a cytokine storm, which leads to death. Professor Clark will screen for agents that can prevent or halt a cytokine storm, with and without Tamiflu. Leader of the study into how GP's could contribute to controlling an influ...
Hopkins researchers discover genetic switch that turns off an oxygen-poor cell's combustion engine
...der the burden of making ATP by being prodded into overdrive
by HIF-1. And left to itself during hypoxia, the mitochondrion produces reactive oxygen species that threaten the life of the cell. "But our discovery clearly shows that hypoxia doesn't simply trigger a passive shutdown of the mitochondrion," said D...
Boost for new cancer therapies
...in normal cell division but that it also goes into overdrive
in cancer helping cells to multiply in an uncontrolled way. Clinical trials on drugs that block the actions of Polo kinase started in the United States last year but the complete picture of how the enzyme assisted the cell-division process has not ...
Targeting the adrenal gland could be key strategy against heart failure, Jefferson scientists show
...a molecular mechanism involved in such sympathetic overdrive
in heart failure, adds study first author Anastasios Lymperopoulos, Ph.D., a postdoctoral fellow in the Center for Translational Medicine, and means that adrenal gland GRK2 becomes a new target for heart failure medications. GRK2 inhibitors would b...
Lancet study shows gene therapy for Parkinson's disease is safe and some patients benefit
...the subthalamic nucleus. This region is working on overdrive
in the disease process and GABA is an inhibitory transmitter and is important in trying to calm this hyper-reactive circuit. The gene therapy would be used to reduce symptoms and not alter the underlying disease process. Finding novel therapies are ...
Immune system 'escape hatch' gives cancer cells traction
...autoimmune diseases, where the immune system is in overdrive
and needs to be slowed down, says Schneck, a professor of medicine, pathology and oncology at The Johns Hopkins University School of Medicine and its Kimmel Cancer Center. The teams latest report built on research initially conducted at the Univ...