Screening for genetic disorders: Need to avoid anxiety
...ndition, including periodic bleeding to reduce the overload of iron. But there may be a more complex and expensive consequence for health services if such people need continuing support and advice. Professor Atkinson said: "Population screening can create a considerable burden of counselling and follow-up fo...Dartmouth Medical School lab blends DNA and technology to aid in crime-solving
...the final verdict." The IML team hopes to ease the overload of cases on the justice system. According to a pr...the final verdict." The IML team hopes to ease the overload of cases on the justice system. According to a presidential initiative on DNA technology, "One of t...Man-made wetland's effectiveness similar to natural marsh
...toring nitrogen," Mitsch said. "The idea is not to overload wetlands in the first place." The three-acre wetland in the study was roughly the size of three football fields and drained a watershed about 14 times that large. It is located in prime agricultural territory in west central Ohio on the shores of Gr...Iron exporter revealed that may explain common human disorder
... degrade ferroportin might therefore curb the iron overload suffered by those with hemochromatosis, Andrews said. Those with excess iron for other reasons, such as repeated blood transfusions, might also benefit from such a drug, she added. The other members of the research team include Adriana Donovan from C...SSRI antidepressants involve dopamine as well as serotonin signaling
...nin syndrome" caused by such situations as dietary overload of serotonin precursors in people taking SSRIs. The researchers wrote that the relationship between dopamine and serotonin signaling "is likely vital for normal behavior and for the pathology that can be treated with SSRIs." The brain area involved, ...JCI table of contents May 1, 2005
...ure can result from chronic hypertension, pressure overload and consequent overgrowth of the organ. In a stud...ohns Hopkins Medical Institutes show that pressure overload causes a protein in the heart, called NOS3, to become a major source of damaging reactive oxygen spe...Newly discovered genetic disease sheds light on body's water balance
...to UCSF Children's Hospital with symptoms of fluid overload and strikingly low levels of sodium in their blood. The first child suffered from severe irritability. A few months later, the second infant was admitted with generalized seizures. Doctors in the pediatric endocrinology and pediatric nephrology servi...Finding the function of fish ferroportin
...portin protein leading to a human disorder of iron overload called type IV hemochromatosis. In a study appearing online on 5 May in advance of the print publication of the June issue of the Journal of Clinical Investigation, Leonard Zon and colleagues provide the first detailed characterization of the adult ...Study finds research participants concerned about genetic discrimination
...s were involved in primary-care screening for iron overload or hereditary hemochromatosis (a metabolic defect causing accumulation of too much iron, leading to organ damage and other serious health problems), and all were told that they were being tested to see if they had too much iron in their blood or carr...Key neural system at risk from fetal alcohol exposure
...tive receptors, you're more susceptible to sensory overload and environmental stimuli can become overwhelming." The new results add to a long list of alcohol's negative effects on the developing fetus. In the last 30 years, scientists have come to understand that exposing the fetus to alcohol, the drug most w...Heme controls antioxidants and iron in ferritin
...nly way to develop new therapies for treating iron overload was to focus on iron metabolism. But a new study published in the October 10th issue of the Proceedings of the National Academy of Sciences is the first to demonstrate that the ferritin gene can be controlled by heme, and other common antioxidant reg...Molecular cabal contributes to stroke damage
...s open to admit calcium into the cell, and calcium overload is central to neuronal death. In their experiments, Gao and colleagues induced ischemia in rat brains, or deprived cultured neurons of oxygen, and analyzed the molecular effects. Their analyses revealed that such deprivation triggered NMDARs, which i...Unexpected link between gene in liver and iron overload
...s. Iron deficiency results in anemia, whereas iron overload leads to organ and tissue damage. Symptoms of hem...xtensive analysis, the team detected a significant overload of iron in tissue samples taken from the mutant mice. After reaching 2 months of age, the animals ac...Argonne researchers confirm lead in Beethoven's illness
...olid evidence that Beethoven suffered from a toxic overload of lead," Walsh said. "In addition, the presence of lead in the skull suggests that his exposure to lead was not a recent event, but may have been present for many years." The half life of lead in the human body is about 22 years, with 95 percent of ...New data show Ferriprox is more efficacious than deferoxamine
...ding the European Union, for the treatment of iron overload in patients with thalassemia major for whom deferoxamine therapy is contra-indicated or who present serious toxicity with deferoxamine therapy. STUDY I DETAILS: Randomized Controlled Trial of Deferiprone or Deferoxamine in Beta-Thalassemia Majo...Microbiology text tells stories, offers online resources
...r looking up factual information. "Not wanting to overload this book with information, we turn you to the wealth of material available on the internet," says Schaechter. Purchase of the Microbe textbook grants instructors and students access to two Web resources. The Microbe website is designed to amplify ...International policy workshop on nitrogen in Paris March 8 10, 2006
...he scientific community to the effects of nutrient overload on the environment. The issues of Nitrogen encompass more than nutrients. They cover a wide area including air pollution, greenhouse effect, and stratospheric ozone depletion, among others. These all require an integrated policy approach. The In...Researchers explore new technique to treat high blood pressure, kidney damage
...old weather, which can constrict blood vessels and overload the kidneys with hormones, according to findings published online recently in the journal Gene Therapy. Using a corrective gene, scientists were able to block a protein in the kidneys that triggers high blood pressure and kidney damage, said Zhongjie...Losartan prevents life-threatening insulin resistance in burn injuries
...lin resistance occurs when the body senses glucose overload and attempts to reduce it by producing more insulin. When the additional insulin is unable to moderate the glucose, the body releases even more insulin. The result: elevated levels of both glucose and insulin. Burn-related insulin resistance can last...... 2003. Mussels, however, can help control nutrient overload and hypoxia by consuming phytoplankton, which reduces bottom-dwelling bacteria. "When we lose mussels, we may be losing the ability to prevent future dead zones from forming," Altieri said. "So these sorts of extinctions may trigger a downward spiral...