UCSD discovery opens new avenues for design of anti-tumor medications
The response of blood vessels to low oxygen levels may be the Achilles' heel of a developing t...st to examine how blood vessels respond to the low oxygen conditions that result from the presence of a growing tumor. Previous work by the UCSD group and ot...JCI table of contents, November 15 2004
...hemoglobin in beta-thalassemia Hemoglobin carries oxygen throughout the body and is comprised of four subun...subunits unpaired and alpha-Hb production of toxic oxygen molecules reduces the lifespan of circulating red blood cells. In the November 15 iss...Discovery of real-time natural gas formation offers prospect for renewable energy resource
...s production entirely by exposing the organisms to oxygen or heat sterilization. This finding holds the potential of turning what is today thought to be a finite energy resource into a renewable source of natural gas that could potentially go on for hundreds of years." LUCA be...Heart protein could be used to repair damage caused by heart attack
...tronger heart muscle cells that can resist the low oxygen conditions after a heart attack. The next step, Dr. Srivastava said, is to determine the most effective dose, the optimal time to administer Thymosin beta-4 and how long after an attack the protein can be given to be effective. Othe...'Lighter than air' breathing more than doubles COPD patients' exercise endurance
...athing a low-density mixture of 79% helium and 21% oxygen (called heliox), the length of time that 12 COPD patients could do real exercise was 9 minutes, versus only 4.2 minutes for 12 patients breathing regular air (79% nitrogen/21% oxygen). And the exercise involved wasn't trivial: The subjects cycled "un...New study by UGA researcher shows that Salmonella uses hydrogen as an energy source
...ella is coupled to a respiratory pathway that uses oxygen as the terminal electron acceptor. This permits growth of the pathogen. Maier believed that these enzymes might enable bacteria to glean energy from the splitting of molecular hydrogen. Because the high-energy gas produced by the reactions of ...Promising results in the battle against incurable ALS muscle disease
...od vessels. To a large extent, a tissue in need of oxygen manufactures the protein, thereby developing new blood vessels so that the need for oxygen again diminishes. VEGF also helps neurons survive under stressful conditions. Last year, the work of...Citrus shows promise for certain childhood cancer
...hrough a test to see whether they would quench the oxygen radicals cancer-causing substances that are destructive to normal cells. The limonoids appeared to be as effective as vitamin C in some of the tests. Test of cell viability were more impressive, however. The neuroblastoma cells were all dead within...Shark cartilage cancer 'cure' shows danger of pseudoscience
...wth of new blood vessels that supply nutrients and oxygen to malignancies. "The fact is that it is possible that highly purified components of cartilage, including from sharks, may hold some benefit for treatment of human cancers," Ostrander said. "The key will be to isolate these compounds and desig...Exercise doesn't work for us all
...ple, the team found that training improved maximum oxygen consumption, a measure of a person's ability to perform work, by 17 per cent on average. But the most trainable volunteers gained over 40 per cent, and the least trainable showed no improvement at all. Similar patterns were seen with cardiac output, ...Revisiting the vertebrate invasion of the land
...exercise on the partitioning of aquatic and aerial oxygen uptake in the Pacific tarpon. Beach spawning provides habitat segregation at different points in the life history, with air emergence early in the life cycle and a return to water at hatching. With regard to excretory nitrogen metabolism, modern...Researchers discover direct link between agricultural runoff and massive algal blooms in the sea
...ng periods of time. Another concern is hypoxia, or oxygen depletion, which is caused by excessive algae grow... is consumed by bacteria, which use up most of the oxygen in the water as they multiply. The result is an oxygen-depleted dead zone at the bottom of the sea w...MIT team aims to mend broken hearts
...k-Novakovic said. That depends on providing enough oxygen to cells throughout the tissue. To that end, they ...th a synthetic blood that can carry large loads of oxygen to the cells. Currently the researchers are working to merge the electrical stimulation technique wi...UCSB makes important advances in studies of retinal detachment
...successful in humans. They have determined that oxygen therapy for retinal detachment, which they pioneer... UCSB researchers decided to test the use of extra oxygen to help maintain the cells after a retinal detachment. First reported by the UCSB researchers in 199...New pathway identified in angiogenesis
... "When tumors reach a certain size, they need more oxygen and nutrients to continue to grow. New blood vessels play an important role in tumor metastases, and it is the tumor's production of VEGF that is the key driver of new blood vessel formation," says Clay Marsh, director of the division of pulmonary, c...New effects of an antihistaminic against cerebral injury
...s from rats' brains. The cells underwent a lack of oxygen and glucose analogous to that which they suffer, w...treatment is initiated six hours after the lack of oxygen and glucose, and maintaining it over a 24-hour period, this substance reduces by a quarter the numbe...JCI table of contents, December 15 2004
...ls of obese mice produce increased levels of toxic oxygen molecules known as reactive oxygen species (ROS) as well as the enzyme NADPH oxidase. Furthermore, these cells express decreased levels...Oxidants link obesity to diabetes
...ls of obese mice produce increased levels of toxic oxygen molecules known as reactive oxygen species (ROS) as well as the enzyme NADPH oxidase. Furthermore, these cells express decreased levels...National study finds second cesarean section safer than normal delivery
...found that one complication of birth insufficient oxygen supply to the brain that can lead to acute brain injury "was significantly greater among the infants of women who underwent a trial of labor" than among the infants of women who elected a second cesarean. "The rate was eight per 10,000 in the attemp......w their flying abilities are affected by the lower oxygen and thin air of higher elevations. The results, which appeared this week in the Proceedings of the National Academy of Sciences (PNAS) Online Early Edition, show a clear decline in hummingbirds' lifting ability with altitude, not unlike that seen in ...