Study shows naturally occurring proteins protect against rapid tumor growth
...n whose laboratory first proposed the angiogenesis paradigm more than 30 years ago. "This is a landmark paper because it provides genetic proof that endogenous inhibitors of angiogenesis circulating in the blood may protect us from the disease of cancer and is the first demonstration that a mild increase in o...The BIOS Initiative - open source biotechnology is born
...these new tools are provided under a new licensing paradigm that ensuresthat they are improved, shared and retained as a public resource." Today also sees the launch of BioForge ( www.bioforge.net ), an online collaborative researchplatform for biological innovation, developed in partnership with CollabNet In...'Man the Hunter' theory is debunked in new book
...idea of "Man the Hunter" is the generally accepted paradigm of human evolution, says Sussman, who recently served as editor of American Anthropologist. "It developed from a basic Judeo-Christian ideology of man being inherently evil, aggressive and a natural killer. In fact, when you really examine the fossil...Research using mouse models reveals a novel key player in the initiation of colon cancer
...ation of tumor formation. This study sets a new paradigm for gastrointestinal tumorigenesis, in that genetic events outside the epithelial layer itself have a profound effect on tumor initiation. Thus it appears likely that this study will foster additional research into other mesenchymal genetic modifier...University of Pittsburgh receives award to study new theory of breast cancer development
...g, this very knowledge may provide a promising new paradigm to understanding the growth and spread of cancer. The project will examine a subset of highly malignant cells in breast cancer tumors, which resemble adult stem cells, and may be responsible for the development of breast cancer. Referred to as tumor...Fundamental finding yields insight into stem cells, cancer; opens door to drug discovery
...naling pathway provides a previously unappreciated paradigm for its role in promoting growth, differentiation, and malignancies." The finding in zebrafish could lead to new drugs that block the growth of tumors by disrupting the beta-arrestin2 protein's normal function, the researchers said. In other cases, d...Study in Royal Society journal on first evidence for magnetic field detection in sharks
... and genotypic diversity: an antibiotic resistance paradigm by Dr LA Dugatkin, Dr M Perlin, Dr J Scott Lucas and Dr R Atlas How traits that benefit others evolve has been a perennial mystery for evolutionary biology. We chose antibiotic resistance as a test case for looking at the evolution of group-benefici...New tuberculosis antibiotic may shorten treatment time, fight drug-resistant strains
...for humans, it could lead to a change in treatment paradigm for tuberculosis," Andries said. The drug belongs to a family of compounds called "diarylquinolines," or "DARQs" recently patented by Johnson & Johnson. The research team identified this family by screening a large number of compounds from its chemic...Rethinking new therapies for Crohn's disease at U.Va.
...n the early stages of Crohn's disease. The classic paradigm held that cytokines secreted by type 1 T-cells, such as TNF (tumor necrosis factor), interleukin-12 and interferon-g were primarily responsible for Crohn's, while type 2 cytokines were linked to ulcerative colitis, another type of inflammatory bowel ...US DHS sponsored evaluation confirms superior performance of Response Biomedical's RAMP anthrax test
...nutes, anywhere, every time. RAMP represents a new paradigm in diagnostic testing, with the potential to be adapted to more than 250 medical and non-medical tests currently performed in laboratories. The RAMP System consists of a portable fluorescent Reader and single-use, disposable Test Cartridges. RAMP tes...Sandbagging cancer in the bloodstream
...e VEGF or its downstream target Src is an emerging paradigm for fighting cancer. In fact, the U.S. Food and Drug Administration recently approved Avastin, a VEGF inhibitor, for fighting colorectal cancer. However, VEGF is unique among growth factors in that it also causes vascular permeability where it is re......ating events. These investigators have developed a paradigm that can distinguish antisocial from normal children on the basis of brain waves recorded during performance of a frustrating task. In this study they showed that a 14 week behavioral treatment program aimed at helping antisocial children who are agg...