Highlights of American Anthropological Assoc. meeting
...elanesia and Beyond: Panelists will scrutinize the paradoxical proliferations of magical forms in a modernized world. (23.45 p.m.) Emergent Representations: Violence, Ethnography and the Everyday: A panel discusses the challenges of violence to everyday lives. (25.45 p.m.) Food, Ritual and Home: Fo...Genetic defect confers risk of major depression, resistance to SSRI drug therapy
...other variants of the gene might also explain such paradoxical adverse reactions to SSRI treatment as suicidal behavior and SSRI-exacerbated mania and psychosis. The Duke team reported its findings Dec. 9, 2004, in the early online edition of Neuron . The work was supported by the National Institutes of Health...Deficiency of growth hormone and IGF-1 reduces cancer and kidney disease, but creates other problems
...ulin-like growth factor 1) on adult rats and found paradoxical effects, according to William E. Sonntag, Ph.D., professor of physiology and pharmacology at Wake Forest University Baptist Medical Center and the lead investigator. "Things that happen when you are an adolescent may have an impact on how long you li...Discovery of an American salamander where it shouldn't be: Korea
...vered in heavily populated Sri Lanka. "It's a very paradoxical situation. On the one hand, amphibians are declining, and they are in terrible difficulty, and on the other, we are discovering new species," said Wake. "I think there still are a lot of surprises to come in, especially with respect to nocturnal orga...Protease inhibitors reach beyond HIV
...t higher concentrations. The mechanisms for these paradoxical data are unclear, as is whether PI therapy would aid CD4 T cell reconstitution in HIV patients in vivo. In a study appearing online on June 2 in advance of the print publication of the July 1 print issue of the Journal of Clinical Investigation , A...JCI table of contents July 1, 2005
...t higher concentrations. The mechanisms for these paradoxical data are unclear, as is whether PI therapy would aid CD4 T cell reconstitution in HIV patients in vivo. In a study appearing online on June 2 in advance of the print publication of the July 1 print issue of the Journal of Clinical Investigation , A...An existing diuretic may suppress seizures in newborns
...es chloride to move out of nerve cells, creating a paradoxical excitatory reaction that may actually exacerbate seizures. To better understand this paradox, the researchers focused on two molecules that regulate cellular chloride levels: KCC2, which transports chloride out of cells, and NKCC1, which brings chlo...AKT cancer cell pathway demonstrates unexpected function
... breast cancer, the PI3K/AKT pathway, also plays a paradoxical role in suppressing the ability of the tumor to invade new tissues," says Lewis Cantley, PhD, director of the division of signal transduction at BIDMC and professor of systems biology at HMS, in whose laboratory the PI3K pathway was first discovered....NJIT solar physicists report paradox: Less sunlight, but temps rise
...ecreased." The scientists find that the seemingly paradoxical result is due to an increase in the cloud cover coupled with a peculiar re-arrangement of the clouds, but are unsure why this is happening. This large variability of the clouds and albedo presents a fundamental, unmet challenge to our ability to unde...Ironman study redefines fine-tuned: Balance training time with blood pressure variability
...ic modulation of vasomotor tone, and they showed a paradoxical increase in parasympathetic modulation of the sinus node after active orthostasis," or standing, the paper reported. "Seven of the 23 subjects fainted in response to active orthostasis [defined by moving from a lying to standing posture] -- and all o...Low dose vitamin A derivative does not prevent head and neck tumors, clinical trial finds
..."It is now important to uncover the basis for this paradoxical lack of isotretinoin clinical chemoprevention activity."...Eat less, weigh more? Enzyme makes lean mice 'susceptible' to dietary fat
...in why the absence of CPT1c may have its seemingly paradoxical effect. Under normal circumstances, says Wolfgang, body weight is maintained by a combination of food intake and energy expenditure, how hungry the body is, and how much energy cells need. Many cells in the body use a sugar called glucose as a sourc...Weizmann Institute scientists discover a molecular security mechanism for keeping mutations in check
...different careless enzymes. Although this may seem paradoxical intuitively, more careless enzymes should mean more mutations each of these enzymes is tailored to deal with certain specifics types of DNA damage. This specialization is what keeps the level of mutation, and thus the cancer risk, low. But the exi...News tips from The Journal of Neuroscience
... Kawaguchi, Takeshi Shimada, and Akemichi Baba The paradoxical therapeutic actions of psychostimulant drugs in people with attention deficit and hyperactivity disorder (ADHD) are still mysterious. This week, Tanaka et al. shed some light on this question in mice lacking Adcyap1 , the gene that encodes PACAP (pi...Ritalin packs punch by elevating norepinephrine, suppressing nerve signal transmissions
...want to unlock the mystery of why the drug has the paradoxical effect of decreasing hyperactive behavior and increasing the ability to focus, even though it is a stimulant, said Barry Waterhouse, the study's senior author. "We're developing a series of behavioral and electrophysiological assays for examining the...Pathway toward gene silencing described in plants
...y the de novo cytosine methyltransferase, DRM2. A paradoxical aspect of the pathway is that siRNAs direct DNA methylation but DNA methylation is also required for the production siRNAs. "It's a circular pathway. You have to produce the siRNA in order to have them come back and methylate the loci, which someho...JCI table of contents: Nov. 1, 2006
....php?id=28639 ACCOMPANYING COMMENTARY TITLE: The paradoxical patent ductus arteriosus AUTHOR CONTACT: Deepak Srivastava University of California San Francisco, San Francisco, California, USA. Phone: (415) 734-2716; Fax: (415) 355-0141; E-mail: dsrivastava@gladstone.ucsf.edu . View the PDF of this article at...Heavy smoking cuts women's chance of pregnancy -- even with donated oocytes
...t in others. "It is already known that there is paradoxical dose-dependent effect of nicotine on ovarian tissue. Maybe the same effect is happening in uterine tissue. The effect of a certain molecule depends, not only on its concentration, but also on the concentration of its receptors and all the other molec...News tips from the Journal of Neuroscience
... rat MSNs during wakefulness, slow wave sleep, and paradoxical sleep. Previous studies, largely carried out in anesthetized animals, had reported that MSNs undergo rhythmic membrane potential fluctuations between a hyperpolarized quiescent down state and a depolarized up state associated with action potential di...Scientists find hormone activity explains adolescent mood swings
...ress also increased anxiety at puberty, due to the paradoxical effects of this hormone that is released by stress. Dr. Smith and colleagues identified the site on human recombinant alpha4-beta2-delta GABA-A receptors that produced the anxiety response, and were able to mutate the site to prevent the novel eff...