One-of-a-kind imaging probe reveals secrets useful for drug discovery
...d walking stick venom to demonstrate the technique partly because it combined lead researcher Aaron Dossey's passion for studying insects with his formal training in biochemistry. "I've raised different species of walking sticks, which are well known to spray defensive venom," Dossey said. "We thought if t...UW researchers link deadliness of 1918 flu to severe immune system response
...e host's own overzealous immune-system response is partly to blame for the strong effects of the flu strain, then researchers may be able to treat the virus by targeting the host's immune system. "We're trying to find targets in the host, instead of just in the virus itself," said Dr. Michael Katze, profes...Mature muscle fibers can revert to become cancerous, researchers find
...lls that surround or form them. The question arose partly because of the number of nuclei found in each cell. The tumor cells each have a single nucleus, while developed muscle tissue contains many nuclei up to several hundred. The muscle cells are surrounded by satellite cells, which can develop into mat...Increase in drug development for killer diseases is not enough
...eglected diseases are increasingly being developed partly due to the use of public-private partnership (PPPs) mechanisms that spread the financial and organisational risk of product development. Anne-Laure Ropars, from the George Institute will be discussing the rise of drug development for neglected disea...Widespread elephant slaughter discovered in Chad
...was missed in the second count. The latest survey, partly funded by National Geographic, was commissioned to assess the level of poaching during the wet season, when the elephants wander outside park limits to forage and are vulnerable to attack. Elephants in the park have enjoyed strong protection from th...Researchers devise new tools to help pinpoint treatments for heart failure
...an Diego describe the use of an engineered protein partly derived from a jelly fish that fluoresces within heart cells in tandem with activation of the key enzyme called PKA (protein kinase A). By combining computer modeling with the novel fluorescence-imaging technique in living cells, the researchers were......ion (+60% in speed, +39% mechanical power) is only partly explained by the lower cost of loaded walking (-20%), being also the result of a better cardio-circulatory adaptation to altitude, which generates a higher mass specific metabolic power (+30%). Consequently, Nepalese porters show higher efficiency, b...Figuring out function from bacteria's bewildering forms
... coil, Stella a star and Clostridium cocleatum a partly eaten donut? No one really knows. A new report in the Proceedings of the National Academy of Sciences by Indiana University Bloomington scientists answers that form-and-function question for one bacterium, the aquatic Caulobacter crescentus, whose...Corals switch skeleton material as seawater changes
...n acidification, which are believed to be at least partly human caused." His team's experiments do, however, have significance with respect to global warming and ocean acidification, Ries said, because they reveal that although corals can adapt mineralogically to altered seawater chemistry, doing so slowe...Study contradicts USA warning that an antidepressant can cause congenital abnormalities
... of pregnancy because of a combination of reasons: partly because of their depression, but also because of confusion caused by information on possible damage to the foetus from the package labelling. "Our prospective controlled follow-up study does not support the assumption that paroxetine can cause congen...Mosquito immune system examined
...by its capacity to transmit malaria, may therefore partly depend on the mosquito's microbial exposure, which can differ greatly between different geographic sites. Potentially, we could boost the mosquito's capacity to fight the malaria parasite by exposing it to certain microbes or compounds that resemble ...Loss of central vision with age may be linked to quality of dietary carbohydrates
...ision loss in older adults and a person's risk may partly depend upon diet. When it comes to carbohydrates, quality rather than quantity may be more important, according to new research by Allen Taylor, PhD, director of the Laboratory for Nutrition and Vision Research at the Jean Mayer USDA Human Nutrition ...Light-to-moderate prenatal alcohol exposure can lead to cognitive deficits 10 years later
...atory animal and human studies show that it may be partly explained by genetic factors." "Similar findings have been described in other studies," concurred Connor, "however, it should not be construed that a child is protected from the damaging effects of prenatal alcohol exposure because of their ethnici...Protowings may have helped bird ancestors cover rough terrain
...mprovement in fitness would result from ancestral, partly evolved wings. Two theories have recently dominated the debate: one postulates that flight evolved in tree-dwelling ancestors that used their forelimbs to help them glide, while the other considers ancestral birds to be terrestrial dinosaurs that dev...Whole-genome study at Johns Hopkins reveals a new gene associated with abnormal heart rhythm
...l's QT interval remains constant. This interval is partly dependent on one's genetic constitution and, moreover, genes also play a role in sudden cardiac death. "There's a great deal of evidence out there that having a too long or too short QT interval is a risk factor for sudden cardiac death," says the s......he way people age, and how fast they age, could be partly due to variations in their WRN proteins. "Should this be the case, knowing the structure of WRN will be crucial for understanding how slight variations in the protein might alter its function," she says. "Ultimately, scientists might be able to use t...Even at small scales, the big decisions are made at the water cooler
...o listen in on up to 200 cells in the near future, partly in the hopes of testing these predictions. "We all know biological systems, from the tiniest cell up to the largest whale, are more than the sum of their parts," Bialek said. "The individual parts aren't alive, but when they come together they are. I...New groundbreaking findings in taste, smell and chemical irritation
...r extremely sweet solution and for sweet foods are partly genetic...Mankind benefits from eating less meat
... a "protein transition". We must eat less meat and partly replace our protein requirements with so-called Novel Protein Foods (NPFs). These NPFs are based on plant proteins that are derived from, for example, peas or soya. While we don't all have to adopt a vegetarian diet, a change in production is necessa...Mutation in blood stem cells provides clues to cancer development
...lenge in fighting certain forms of blood cancer is partly due to a reservoir of leukemic stem cells that are resistant to current therapies. The discovery of the JAK2 mutation in stem cells in patients with PV is an important first step in developing treatments which target the earliest population of cells...