Tag: "pathways" at biology news
Scientists find major susceptibility gene for Crohn's disease
...oronto, the findings highlight numerous biological pathways
not previously thought to play a role in Crohn's disease. "The identification of the PHOX2B gene in this study, for example, may implicate a role for neuroendocrine cells of the intestinal epithelium as having a role to play in Crohn's disease. In ...
Quantum secrets of photosynthesis revealed
... to simultaneously sample all the potential energy pathways
and choose the most efficient one. Fleming is th...tion states) that can explore all potential energy pathways
simultaneously and reversibly, meaning they can retreat from wrong pathways
with no penalty. This fi...
LSU professors monkey around with the Rhesus Macaque genome
...nsortium. "It provides additional insight into the pathways
involved in the infection and spread of pathogens in primates, which could potentially lead to the development of new and improved treatment options, vaccines and other preventative measures in humans." Mobile elements, an integral part of this stu...
JCI table of contents: April 12, 2007
... are better than one: two dysfunctional DNA repair pathways
kill tumor cells Individuals who inherit two mutant copies of any one of about 12 genes that make the proteins of the Fanconi Anemia (FA) pathway develop FA, which is characterized by increased incidence of cancer and bone marrow failure, among o...
Study pries into ovarian cancer's deadly secrets
...team report that defects in two cellular signaling pathways
occur together in a subset of ovarian endometrioid...oteins that alter the normal function of signaling pathways
in cells. Defects in these pathways
can prevent the normal action of tumor suppressor genes and allo...
New study zeroes in on genetic roots of Alzheimer's
...of The Journal of Neuroscience and may lead to new pathways
for development of Alzheimer's therapeutics. Approximately 15 percent of the population carries a gene that causes their bodies to produce a lipoproteina combination of fat and protein that transports lipids (fats) in the bloodknown as apolipoprote...
Mouse FH knockout resembles human renal cell cancer
...is providing valuable insight into the biochemical pathways
that are associated with development of renal cyst...se model advances the understanding of biochemical pathways
linking mitochondrial dysfunction and tumorigenesis and will allow testing of potential therapies fo...
Scripps research study shows humans and plants share common regulatory pathway
...the value of drawing on plant studies of R protein pathways
to better understand the pathogen recognition func...tional proteins have been linked to the activation pathways
of the R protein in plants. "The NLR family has clear links to human disease," Ulevitch said. "Ou...
How do the rules of immunity change during chronic infections?
...nt type of T cell that is not governed by the same pathways
and mechanisms." Understanding how the bodys immune response operates during chronic infections, and why it fails to clear these infections, could help scientists design more effective therapies to fight chronic infections and certain types of tumo...
JCI table of contents -- April 5, 2007
... utility.” TITLE: Crosstalk between Gi and Gq/Gs pathways
in airway smooth muscle regulates bronchial contractility and relaxation AUTHOR CONTACT: Stephen B. Liggett University of Maryland School of Medicine, Baltimore, Maryland, USA. Phone: (410) 706-6256; Fax: (410) 706-6262; E-mail: sligg001@umaryland...
Discovery of 'master switch' for the communication process between chloroplast and nuclei of plants
...ed Koussevitzky: "Were trying to put the signaling pathways
in the context of the plants stress response. It will take a little more tweaking, but at least knowing that it is going through a certain particular pathway will enable researchers to design what the targets should be downstream from these pathways....
NYU scientists identify how development of different species uses same genes with distinct features
...fer new insight into the workings of developmental pathways
across species. The study is published in the latest issue of the journal Science. The researchers examined the fruit fly Drosophila and the wasp Nasonia as genetic model systems. Fruit flies development is well-understood by biologists and therefo...
Estrogen protects liver after traumatic injury
...emorrhage. They examined the cell surface receptor pathways
by treating rats with a form of estrogen that cann...nase A. By identifying GPR30 and the downstream pathways
(Bcl-2 and active protein kinase A) involved in estrogens beneficial effects, Chaudrys group has pro...
Research project tackles 'regeneration' gap
...s possess some of the same genes and communication pathways
used by some of natures most remarkably regenerative animals. Already, UF McKnight Brain Institute scientists have discovered more than 100 genes associated with all major human neurological diseases in a simple marine snail, as well as more than ...
All roads lead to GUN1
... nucleus but not much is known about the signaling pathways
between chloroplasts and the nucleus says the study's lead author, Joanne Chory, Ph.D., professor and director of the Plant Biology Laboratory and investigator with the Howard Hughes Medical Institute. The basis of the study may provide insight in...
Advances in personalized medicine on agenda for 54th Society of Nucelar Medicine Annual Meeting
... and others) to "photograph" biological targets or pathways
in the bodyand its therapy value will be at the forefront of personalized medicine, eventually providing patient-specific information that allows tailored treatment of disease," he added. "Nearly 2,000 scientific and technologist studies will be pr...
UBC researchers find new superbug weapon for near-empty antibiotics arsenal
...Data showed that IDR-1 activates several signaling pathways
to stimulate infection-clearing chemokines a chem...recognize and kill pathogens, as well as signaling pathways
that trigger biological responses. The researchers anticipate the therapy may be useful as a suppl...
Study shows metabolic strategy of stressed cell
...gs of enzymes host a series of complex biochemical pathways
that produce the energy-rich molecule ATPthe cell'...by shutting down or limiting the other biochemical pathways
that use CoA, the cell can concentrate it in the mitochondria where it's needed most." "The metab...
Pacific Rim researchers to collaborate on distributed bioinformatics analysis of avian flu
...i. "This will allow us to analyze the biosynthetic pathways
of viruses as well as the signal transduction pathways
for clues to understanding how avian flu interferes with human metabolism." The Asian institutions...
Lung cancer-derived EGFR mutants exhibit intrinsic differences in inhibitor sensitivity
...ine kinase that plays a critical role in signaling pathways
controlling cell proliferation and survival. Although the specific mechanisms are unclear, studies have shown that some EGFR mutations are associated with increased sensitivity to small-molecule tyrosine kinase inhibitors. To better understand how di...
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