Tag: "pathways" at biology news

Dr. John A. Martignetti receives 2006 Prostate Cancer Foundation Award

...cus their efforts on discovering new ideas and new pathways for prostate cancer treatment strategies. Prostate cancer is the most common non-skin cancer in the United States, striking one in six men. In 2007 alone, more than 218,000 men will be diagnosed with prostate cancer and more than 27,000 men will d...

Plant size morphs dramatically as scientists tinker with outer layer

... be used by agronomists to manipulate plant growth pathways to maximize crop yield, or even reduce leaf size or leaf angle in plants that need to be spaced closely together, says the study's lead author, Joanne Chory, Ph.D., professor and director of the Plant Biology Laboratory and investigator with the Howa...

Solar energy conversion offers a solution to help mitigate global warming

...designer plants, connecting natural photosynthetic pathways in novel configurations and using artificial bio-inspired nanoscale systems. Heat controlling the size, density and distribution of nanodot inclusions during bulk synthesis could enhance thermoelectric performance and achieve more reliable and i...

Blood tests may be possible for mental health conditions

...n, the finding could help us better understand the pathways that initiate, promote and maintain panic disorder." The team compared gene expression in lymphoblasts (immature white blood cells) culled from 16 participants with panic disorder and 17 participants without the disorder. The study found many genes...

Penn researchers discover new molecular path to fight autoimmune diseases

...ng enzyme, the FOXP3 protein functions to turn off pathways that would lead to autoimmune diseases. "I think this simple approach will revolutionize the treatment of autoimmune diseases in humans because we have a new set of enzymatic drug targets as opposed to the non-specific therapies we now use," says G...

Whole body regeneration from a blood vessel

..., sea squirts share several fundamental biological pathways with vertebrates; consequently, using them as a model system to study WBR could illuminate not only the evolutionary origin of regeneration, but also its subsequent attenuation in vertebrates....

New success in engineering plant oils

... better understanding of the enzymes and metabolic pathways that produce these oils to find ways to manipulate the accumulation of fats using genetic techniques." The researchers focused on an enzyme known as KASII that normally elongates fatty acid chains by adding two carbon atoms. The longer 18-carbon ch...

Studies force new view on biology of flavonoids

.... They appear to strongly influence cell signaling pathways and gene expression, with relevance to both cancer and heart disease. "We can now follow the activity of flavonoids in the body, and one thing that is clear is that the body sees them as foreign compounds and is trying to get rid of them," Frei sai...

A key to male fertility

...suggests that it is worth exploring the signalling pathways controlled by SHP in men suffering from fertility disorders. Puberty is the result of endocrine alterations programmed from the moment of sexual differentiation in the embryo and ftus. It is characterized by anatomical alterations: the maturation ...

Green tea and COX-2 inhibitors combine to slow growth of prostate cancer

...e a synergistic effect -- each triggering cellular pathways that, combined, are more powerful than either agent alone, said Hasan Mukhtar, Ph.D., professor of dermatology at the University of Wisconsin and member of Wisconsins Paul Carbone Comprehensive Cancer Center. We hope that a clinical trial could lead...

Rare mutation causes early heart disease and metabolic syndrome

...hway, Wnt, has large effects on multiple metabolic pathways that contribute to cardiovascular disease," said Mani. Coronary artery disease (CAD) is commonly caused by metabolic syndrome, which includes a constellation of risk factors such as high low-density lipoprotein (LDL) cholesterol, high triglycerides,...

Lessons in wood formation from Arabidopsis

...ant Arabidopsis. The presence of similar genes and pathways in tree species suggests that they may play a role in the regulation of wood formation in trees. In the first paper, Masaru Ohme-Takagi and colleagues at the National Institute of Advanced Industrial Science and Technology in Japan, the Japan Scie...

Proteasome activator enhances survival of Huntington's disease neuronal model cells

...ed in either non-ubiquitinated protein degradation pathways (PA28) or subunits of PA700, the 26S proteasome ub...le to intervene therapeutically in the proteolytic pathways and organelles that participate in the specific degradation of misfolded and abnormal proteins. ...

MIT bioengineer advances survival, promise of adult stem cells

...eptors on the stem cell surface, it activates many pathways that can influence stem cell proliferation, migration and differentiation. However, the cell normally absorbs EGF and degrades it, and the growth factor loses its power to influence cell behavior. This has made EGF notoriously difficult to develop as...

Ingredient in Big Macs and sodas can stabilize

...files of such gold nanoconstructs will open up new pathways for the intratumoral delivery of gold nanoparticles in diagnostic imaging and therapeutic applications for cancer," Amiji said. The new generation of trimeric amino acids peptides discovered by Katti in 1999 (referred to by Amijii as 'Katti Peptid...

Genes and genius: Researchers confirm association between gene and intelligence

...dence to date that a gene that activates signaling pathways in the brain influences one kind of intelligence. ... The CHRM2 gene activates a multitude of signaling pathways in the brain involved in learning, memory and other higher brain functions. The research team doesn'...

Experimental Biology 2007: Today's Research, Tomorrow's Health, April 28-May 2

...oimmunity; viruses and human cancer; developmental pathways in cancer progression; new developments in vascular biology; pharmacogenomics and targeted therapies; stem cells for therapeutics; and novel therapies based on molecules of the innate immune system. The American Society for Pharmacology and Exper...

Scientists identify specific enzymes that make meningitis hard to fight

...portant impact for ourunderstanding of the precise pathways of DNA repair and the significanceof the two separate functionalities that act in different DNA repairpathways within the pathogen." Professor Christoph Tang from Imperial's Division of InvestigativeScience added: "After realising that the two enzy...

JCI table of contents -- February 22, 2006

...e, leading the authors to suggest that Akt and the pathways that generate reactive oxygen might provide targets for the development of drugs to treat individuals with advanced stage melanoma. TITLE: Overexpression of Akt converts radial growth melanoma to vertical growth melanoma AUTHOR CONTACT: Jack L. A...

'Bridge' protein spurs deadliest stages of breast cancer

...ing in embryonic stem cells and examines signaling pathways that are involved in obesity and diabetes, has stu...how it influences cancer cell growth. They studied pathways known as Akt and Erk, well-known parts of the Neu oncogene pathway, in the mice lacking Gab-2 and fo...

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(Date:4/17/2014)... available in German . ... protection money demanded of him, he can expect his premises ... as fear of the consequences is enough to make restaurant ... birds, which lay their eggs in other birds, nests. If ... parasites take their revenge by destroying the entire nest. Consequently, ...
(Date:4/17/2014)... fragmentation of forests in the Amazon help create ... to rapid and widespread forest loss during drought ... findings show that forests in the Amazon could ... with forest fires lead to large-scale loss of ... assistant professor of geography, Penn State. , "We ...
(Date:4/17/2014)... in many serious conditions such as heart disease, epilepsy ... drug therapies. Unfortunately, there is still much scientists do ... fresh and unexpected insight into the structure of sodium ... molecules - which are responsible for ,fine-tuning, the activity ... most recent edition of the Journal of Biological ...
Breaking Biology News(10 mins):Fear of the cuckoo mafia 2Fear of the cuckoo mafia 3Drought and fire in the Amazon lead to sharp increases in forest tree mortality 2Drought and fire in the Amazon lead to sharp increases in forest tree mortality 3Structure of sodium channels different than previously believed 2
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