American Chemical Society's Weekly PressPac -- Aug. 1, 2007
...eatments selected according to tumor cell type and patients predicted responses to different kinds of anti-cancer drugs. Their paper describes key features of state-of-the-art proteomic profiling, in which blood tests are used to analyze single proteins and multiple fingerprint protein patterns that are prese...Link identified between Alzheimer's disease and glaucoma
...er this pressure). However a significant number of patients continue to lose vision despite their pressure bei...being used in clinical trials to treat Alzheimer's patients by pharmaceutical companies Elan in Dublin and Wyeth in the US. However, the UK researchers have sho...Research team enlightens the reasons for severe blindness
...g term. LCA itself is so far incurable. However, patients and doctors set their hopes high on gene therapy: ... to this therapy. A clinical study of twelve human patients is currently being carried out at a large-scale London hospital with encouraging results. If these f...UCF research links proteins, stem cells and potential Alzheimer's treatment
...nslate into the human brain, it could give hope to patients and their families. Sugaya, who is the founder of the International Brain Conference at UCF, has been spent his entire career studying the brain. Six years ago, he reported that brain stem cells transplanted into aged rats seemed to become function...Teamwork between 2 key proteins necessary for normal development and regulation of red blood cells
...may point researchers to future gene therapies for patients with sickle cell anemia and beta-thalassemia. In an article pre-published online Aug. 3 as a First Edition Paper in the journal Blood, the journal of the American Association for Hematology, researchers reported that a protein called KLF2 coordina...UF, French scientists seek test to detect gene doping in athletes
...the market, increases red blood cell production in patients with anemia and boosts oxygen delivery to the body. In athletes, this translates to enhanced stamina and a competitive edge. But because synthetic hormones such as EPO are prohibited by WADA and readily detected through drug tests, performance-dri...Multicenter study nets new lung tumor-suppressor gene
... found to be especially fast-growing, for example, patients with such tumors might be candidates for more aggressive therapy. People born with defective versions of LKB1 often develop Peutz-Jeghers syndrome, which is marked by intestinal growths and an increased risk for certain cancers. Non-inherited mutat...Defects in critical gene lead to accelerated lung tumor growth
...s analyzed DNA from 144 non-small cell lung cancer patients treated at UNC and affiliated hospitals. Defects i...s study and ones like it we should be able to sort patients into groups based on exactly what genetic lesion is causing their cancer, said Dr. Neil Hayes, an as...Discredited Korean embryonic stem cells' true origins revealed
...enetically selected cells that could be matched to patients on the genes that control immune rejection. Having all the genetic material come from the mother, as it does in parthenogenesis, reduces tissue compatibility issues. "There has been an advance in the idea that you can couple parthenogenesis and gen...Success or failure of antidepressant citalopram predicted by gene variation
...e based partly on differences in their genes. Some patients respond to the first antidepressant they attempt, ...ication takes weeks to exert its full effects, and patients depression may worsen while they search for a medication that helps. Genetic studies, such as the on...A low expression of MX2 gene exists in the white blood cells of narcoleptics
...nformation from DNA into protein products from 12 patients with narcolepsy with cataplexy and from 12 age- an...ative real-time PCR using a new set of samples: 20 patients with narcolepsy with cataplexy and 20 healthy controls. According to the study, the second screeni...Marijuana component opens the door for virus that causes Kaposi's sarcoma
...ay those with lowered immune systems, such as AIDS patients or transplant recipients, are more susceptible to developing the sarcoma as a result of infection. Their findings, reported in the August 1 issue of Cancer Research, a journal of the American Association for Cancer Research, offer cautionary evidenc...Phase II study of therapeutic vaccine shows efficacy in patients with metastatic colorectal cancer
...effectiveness when given alongside chemotherapy to patients with metastatic colorectal cancer in a phase II tr...nd that six of the 17 metastatic colorectal cancer patients in the study showed tumor shrinkage, classified as complete or partial responses following independe...JCI table of contents: August 1, 2007
...ion sites decreased following transplantation into patients because the treated cells differentiated, the site... sites observed in cells from successfully treated patients were not significantly different from those observed in cells from patients that went on to develop ...U-M researchers find family of 'on switches' that cause prostate cancer
...ing which gene fusion is involved in an individual patients tumor could impact treatment options. If an androg...findings into a test or treatment that will impact patients is central to the new Michigan Center for Translational Pathology. The center brings together expert...Aggressive therapy best for certain AML patients
...S , Ohio A new study suggests that acute leukemia patients whose cancer cells show a genetic change that usua...e mutation called MLL-PTD. Typically, these AML patients responded poorly following treatment with older standard therapies, often relapsing within a year. O...Under magnetic force, nanoparticles may deliver gene therapy
...e tiny, expandable metal scaffolds inserted into a patients partially blocked vessels to improve blood flow. Many stents eventually fail as cells grow on their surfaces and create new obstructions, so delivering anti-growth genes to stents could help keep blood flowing freely. The materials composing the na...New databases put wings on search for bipolar risk genes
...ene hunting, scientists winnow out pure groups of patients with a key characteristiclike those whose bipolar ...otash says. Collecting accurate descriptions of patients in large enough numbers to ensure reliable results is costly and time-consuming, he adds. The Bipol...Pets could be source of multiresistant bacteria infections in humans, MU researchers investigate
...onia. While the infections are most often found in patients after hospitalization, there is an increasing occurrence of community-acquired infections among prison populations, sports teams, military personnel and the general public. Kottler believes that pets might be an important factor behind the increase i......ies, including the good bacteria which can protect patients from pathogenic bacteria. "Antibiotics do not ju...resistance genes within the microbial community of patients treated with antibiotics." Using pigs as a model, Dr Chin and Dr Toni Chapman at NSW DPIs Elizabet...