IRCM scientist demonstrates basic active mechanism of immune-system cells
...phoproliferation" (XLP). Dr. Veillette's discovery paves the way for the development of SLAM, SAP or FynT inhibitors, which could block excessive immune responses observed in patients with autoimmune diseases. ...Genetic discovery paves way to decode sense of smell in mammals
...ment via their sense of smell. The finding in mice paves the way for scientists to unravel the underlying code that allows the brain to interpret smells, according to the researchers. Using genetic manipulations, the team found two proteins in mice that chaperone odorant receptors to the surface of olfacto...Clam embryo study shows pollutant mixture adversely affects nerve cell development
...emonstrating that clam embryos are affected by BCE paves the way for additional studies that may help explain how exposure to BCE affects human nerve cell development and how it might relate to neurological disorders. "We can clearly state that we found an increase in a component of PKA, and PKA is known t...Spectroscopy for the real world
...ing on the surfaces of salt solutions. Their work paves the way for a better understanding of the role played by tiny airborne salt particles, emitted into the air by crashing waves and sea spray, in a slew of atmospheric and environmental processes, such as the destruction of the ozone layer. "This is im...Discovery may lead to better Candidiasis drug
...cific target for histatin," she said. "The finding paves the way for eventually developing a better therapeutic drug for candidiasis." Results of the research were presented today (March 11, 2005) at the International Association on Dental Research General Session being held in Baltimore. Candidiasis al...Key target for Foot and Mouth drug revealed
...gely successful in controlling HIV. The structure paves the way for their development by revealing the atomic details of the key viral enzyme that would serve as a target for drugs. 3C protease's function is to help the virus replicate itself. A drug that binds and inhibits FMDV 3C protease would stop its...Molecular models advance the fight against malaria
...y of the April 29 Journal of Biological Chemistry, paves the way for using these models to test new drugs that could suppress malaria's ability to mutate against current therapy. "This is the first quantitative explanation for malaria's drug resistance," said Dr. Bernard Trumpower, professor of biochemist...BC scientists coax gold particles to emit light strong enough to view single nanoparticles
...most exciting aspects of this technique is that it paves the way for being able to observe behavior in living tissues at the single molecule level," said Fourkas. "The fluorescent molecules commonly used in multiphoton imaging give out only a limited amount of light, 'burn out' quickly under continuous ob...Tadpole soon to help in the fight against cancer and lymphedema
... for the development of this complex network. This paves the way for the search for solutions for illnesses caused by faults in the lymphatic vessel network....Breast tumors in mice eradicated using cancer vaccine
...ology can also be used with the HER-2/neu molecule paves the way for applying this promising cancer vaccine approach to breast cancer. This research was funded by the Department of Defense and the National Cancer Institute. Co-authors are Reshma Singh and Mary E. Dominiecki, both from Penn, as well as Eli...Nocturnal dialysis improves heart disease in patients with end-stage kidney failure
...by the American Physiological Society. "This study paves the way for new therapeutic targets which can potentially improve heart disease in patients with end-stage kidney failure," said Christopher T. Chan, the lead author of the study entitled "Nocturnal hemodialysis is associated with restoration of impa...Substance lining blood vessels may cause cardiovascular disease
...sease and hypertension. This exploratory research paves the way for new studies to examine the exact function that those genes responding to higher ADMA levels may play in cardiovascular disease. In the long term, understanding of the mechanisms associated with increased ADMA levels may lead to new strate...New GM mosquito sexing technique is step towards malaria control, report scientists
...iding a way to quickly sex mosquitoes, the advance paves the way for pooling large numbers of sterile males which could be used to control the mosquito population. Research published online today in Nature Biotechnology, shows how a team from Imperial College London have altered male mosquitoes to express ...Studies on human genome variation provide insight into disease
...ic diversity of this region in humans. "This study paves the way for examining an individual's potential reproductive success based on sequence variants of the LHB/CGB genes," explains Laan. "We may be able to determine whether an individual is particularly susceptible to spontaneous abortions or reduce...Baylor Human Genome Sequence Center key player in mapping human genetic variation
...71/journal.pgen.0010041.eor The completed HapMap paves the way for further disease gene hunts at BCM....Algal protein in worm neurons allows remote control of behavior by light
...ply illuminating animals with blue light. The work paves the way for better understanding of how neurons communicate with each other, and with muscles, to regulate behavior in intact, living organisms. Generally speaking, detailed information about the activity and function of specific neurons during parti...BiovaxID yields 89 percent survival in patients with aggressive non-Hodgkins
...rsity of Texas M. D. Anderson Cancer Center. "This paves the way to use vaccines in a number of hematological cancers that are treated by eliminating diseased B-cells." Biovest is now enrolling patients in a pivotal Phase 3 trial to test BiovaxID against follicular non-Hodgkin's lymphoma (NHL). Follicular...Experimental evolution of yeast in the lab may illuminate early events in speciation
...o one of the fundamental features of evolution and paves the way for a detailed understanding of the genetic changes that turn one species into two....Attack is the best defence against urinary tract infection
...vention of urinary tract infection, a finding that paves the way for radical new forms of treatment. The researchers measured levels of the antibacterial peptide LL-37 in the urine of healthy children and children with a urinary tract infection. They found that the levels were very low in the former group ...New scientific challenges and goals for ESA's Living Planet Program
...arth Explorers will provide new understanding that paves the way for new operational services. This synergy is also highlighted in the Living Planet Programme's strategy for the coming years. With the Living Planet Programme's new strategy in place, ESA will build on past success by continuing to play a c...