How does soy promote weight loss? University of Illinois scientist finds another clue
...the soy hydrolysates so that she can identify each peptide and understand its bioactivity....Lab-on-a-chip device from Berkeley Lab to speed proteomics research
...e emitters achieved a sensitivity and stability in peptide and protein detection comparable to commercial silica-based capillary nanoelectrospray tips. This indicates that our emitters could serve as a critical component in a fully integrated silicon/silica-based micro total analysis system for proteomics." ...Plants tag insect herbivores with an alarm
...ysiology have identified a specific class of small peptide elicitors, or plant defense signals, that help pla..., the insects unwittingly convert this food into a peptide elicitor, which gets secreted back onto plants during later feedings. Recognizing the secreted elici...Scientists identify prion's infectious secret
..., a postdoctoral scientist in Lindquists lab, used peptide arraysglass slides covered with thousands of tiny ...r pathogenic fungi. When the prion was placed with peptide fragments from bakers yeast, the bakers yeast recognition element was activated, and likewise for th...UCLA AIDS Institute researchers find a peptide that encourages HIV infection
...s have discovered that when a crucial portion of a peptide structure in monkeys that defends against viruses,...cteria and other foreign invaders is reversed, the peptide actually encourages infection with HIV. The findings, published in the April issue of AIDS Researc...UCSB Assistant Professor Patrick Daugherty wins Young Investigator Award from ACS
...in engineering, including the development of novel peptide display methodologies, fluorescent protein sensors and library screening methodologies. Daugherty will deliver the Biochemical Technology Young Investigator Award Lecture at the American Chemical Society meeting in Boston in August. The award, whi...UCLA researchers discover link between Parkinson's and narcolepsy
... of up to 60 percent of brain cells containing the peptide hypocretin. In 2000, this same group of UCLA researchers first identified the cause of narcolepsy as a loss of hypocretin, thought to be important in regulating the sleep cycle. This latest research points to a common cause for the sleep disorders as...New NIST reference material for peptide analysis
...graphy (HPLC), and then determine the mass of each peptide using mass spectroscopy. One big uncertainty in this process is that the peptide fragments differ in size, electrical charge and physical properties (such as the speed in which they...News tips from the Journal of Neuroscience
.... Nociceptors that express calcitonin gene-related peptide (CGRP) and Substance P (SP) are normally restricted to lamina I and II. To target axons after a dorsal rhizotomy, Tang et al. used adenovirus to overexpress NGF in the dorsal spinal cord of rats. Three days later, they used more ventral injections to...Yin and yang -- Balance could play key role in progression of Alzheimer's disease
...ablished. Wang set out to determine what role this peptide played in the generation of AB42 aggregates. Wan...his means that the introduction of AB40 to tip the peptide balance toward AB40 could potentially halt or slow down the progression of the Alzheimers in the hum...JCI table of contents -- June 1, 2007
...m the formation of amyloid plaques, made up of the peptide amyloid beta (Abeta), in brain tissue. The role, if any, of inflammation in AD remains somewhat of a mystery. Although the levels of some proinflammatory proteins are elevated in AD brain tissue, whether these proteins have negative or positive effec...New clues to stroke role in Alzheimer's
...r protein called A beta peptide. It is this A beta peptide that is the building block for the amyloid plaques that are a hallmark of AD. The researchers discovered that particular enzymes produced during brain injury, called caspases, somehow also enable BACE to linger in brain cells. Caspases are so-calle...Hormone that signals fullness also curbs fast food consumption and tendency to binge eat
...other hormones involved in weight control, such as peptide YY and leptin, Weyer said. Research in obese rats suggests that amylin may restore the response to leptin, which is often lost in obesity. The hope is that this combination approach will help achieve even greater appetite control and weight loss....Breakthrough developments in rheumatoid arthritis reported
...ed a test to measure for anti-cyclic citrullinated peptide antibody, or anti-CCP. It is now being used as a diagnostic for rheumatoid arthritis. Scientists are now finding that patients have CCP antibodies months or years prior to the illness, suggesting a way to identify the disease before it starts and per...Scientists ponder plant life on extrasolar Earthlike planets
...Maybe it would have the same protein backbone with peptide bonds and so forth. But theres no reason to think it would be comprised of the same 20 amino acids that we have on Earth. Its intriguing to speculate, and I think well know more when we get more clues....JCI Table of Contents -- July 2, 2007
...ration of iron is tightly regulated by hepcidin, a peptide hormone secreted by the liver. High hepcidin level...923 peptide, but not a mutated B16:A insulin B:923 peptide (alanine at position 16 of insulin B chain), rendered CD4+ T cells able to rapidly transfer diabetes...Link between immune system and mammary gland could shed new light on breast cancer
...ast development was controlled by just steroid and peptide hormones. The discovery of this role played by aspects of the immune system will open up new avenues for examining the development of breast cancer, particularly in women who have just had a baby, a time when there is a greater risk of breast cancer....Macrochem acquires option to license pexiganan
... rights for drug uses of pexiganan, a novel, small peptide anti-infective for topical treatment of patients with mild diabetic foot infection (DFI), from Genaera Corporation (Genaera). "We believe this is a unique opportunity for MacroChem to broaden its product portfolio with a product that has already co...Tumor painting revolutionizes fight against cancer
...he operating room. The paint is a scorpion-derived peptide called chlorotoxin that is linked to the molecular beacon Cy5.5.Until now there has been no way to allow surgeons to see tumors live during surgery. Chlorotoxin:Cy5.5 is a fluorescent molecular beacon that emits photons in the near infrared spectru...Tips from the Journals of the American Society for Microbiology
...study researchers identified a novel parasiticidal peptide named longicin from the tick species Haemaphysalis longicornis and tested its ability to inhibit infection. It showed a remarkable ability to inhibit the blood stage of equine Babesia equi by killing the parasites and resulted in reduction of parasi...