Unravelling new complexity in the genome
...n a global scale, which provides a fascinating new perspective on how genes are regulated, Blencowe explains. A challenge now is to figure out how the alternative splicing process is regulated in a cell and tissue-specific manner. In their new paper in Genome Biology, Dr. Yoseph Barash, a postdoctoral fello...European Science Foundation's Forward Look reaches out beyond the endless frontiers
...a sustainable and equitable way over a medium-term perspective (25-40 years). Developing such scenarios requires the involvement of both many scientific disciplines and a broad range of different stakeholders in the food chain. The scenarios activity will raise awareness within Europe about food security and oth...Human knowledge is based upon directed connectivity between brain areas
...nal coupling analysis these results may open a new perspective on brain processes. For the accurate execution of brain functions it might be crucial not only which brain areas are involved but, perhaps even more importantly, how they cooperate with each other. The investigation of this new dimension in brain res...Ability to listen to 2 things at once is largely inherited, says twin study
...es are mostly due to genetic variation, adds a new perspective to our understanding of auditory processing disorders. These disorders may affect as many as seven percent of school-aged children in the United States and often appear alongside language and learning disorders, including dyslexia. APDs also affect o...Scientists find brown fat master switch
...own fat, but there is some, and from a therapeutic perspective the question is whether that pathway can be reactivated." The pathway, according to the new report, is controlled by a gene and protein known as PRDM16 that is found in brown but not in white fat -- the type that stores excess calories and causes w...New findings challenge established views on human genome
...f DNA sequences that have a functional impact. Our perspective of transcription and genes may have to evolve, the researchers state in their Nature paper, noting the network model of the genome poses some interesting mechanistic questions that have yet to be answered. Other surprises in the ENCODE data have m...The wider view from a detailed focus
...oven elements revealed today suggests that "our perspective of transcription and genes may have to evolve," the researchers state, noting that their research "poses some interesting mechanistic questions" that have yet to be answered. Our understanding of genome biology from the Human Genome Project ...Physicist cracks women's random but always lucky choice of X chromosome
...actory apparatus. Coming at the problem from the perspective of a physicist Dr Nicodemi has found an explanation for the random selection based on thermodynamics. Research has already shown that at the key moment in this process both X chromosomes are brought close together within the cell. The Warwick researc...Los Alamos National Laboratory making progress in Groundwater Protection Program
...ys between watersheds. LANL should add a sitewide perspective to its future groundwater monitoring plans. The laboratory also should drill more wells in and between canyons to increase the area of the regional aquifer to be monitored. Data quality issues should be addressed, too. DOE's site office at LANL s...SNM advances professional definition for 'molecular imaging'
... comparisons. Our challenge was to take a broad perspective on molecular imaging while providing concrete information on an emerging scientific and clinical specialty, said David A. Mankoff, chair of SNMs MICOE Standard Definitions Task Force. Input from task force memberswith a broad range of backgrounds and...The first issue of the HFSP Journal is now available
...nd experimental work that offers an intriguing new perspective on the evolution of new functions. The study by Bornberg-Bauer and colleagues addresses the biophysical basis of how mutational paths that seem to be neutral with respect to the dominant phenotype under selection can allow adaptive evolution by selec...Anti-inflammatory drugs interact with HRT, and more
...D4 decline during chronic HIV infection. A related perspective by Rob de Boer discusses the study Citation: Yates A, Stark J, Klein N, Antia R, Callard R (2007) Understanding the slow depletion of memory CD4 T cells in HIV infection. PLoS Med 4(5): e177. doi:10.1371/journal.pmed.0040177 PLEASE ADD THE LINK T...Journal details how global warming will affect the world's fisheries
...mportant economic activity, not the least from the perspective of human nutrition and underdeveloped societies," writes Rognvaldur Hannesson, of the Norwegian School of Economics and Business Administration, in the issues introduction. "Fisheries, due to their primitive nature, are among the human activities mos...Researchers publish first marsupial genome sequence
...me sequence also provides researchers with a fresh perspective on the evolutionary origins of the human genome. It sheds light on the genetic differences between placental mammals, such as humans, mice and dogs, and marsupial mammals, such as opossums and kangaroos. "Marsupials are the closest living relative...LSU professor involved in genome sequencing of the first marsupial
...h," to be sequenced, the opossum provides a unique perspective on the organization and evolution of mammalian genomes. The results will be published in the journal Nature on Thursday, May 10. Marsupials diverged from a common ancestor with placental mammals, a group including humans, approximately 180 million ...Study finds fecal microbes high in New Orleans sediments following Hurricanes Katrina and Rita
...ure. "Our hope is that this data will provide some perspective not just on the immediate impact to the area, but the long term effects of this kind of natural disaster," says Amaral Zettler. "We certainly know a lot more now about the microbial diversity present in Pontchartrain than we did when we started the s...New clues for treatment of disease that causes accelerated aging
...two infants, Miner and his colleagues acquired new perspective on the mutations in progeria. When they compared how much good and bad lamin A was being made in cells from progeria patients and in cells from the infants, they found the infants' cells were making much more bad lamin A. In addition, they found evid...National Academy of Sciences elects 2 Rutgers professors
...y lab," Dooner said. Dooner has brought a fresh perspective to our understanding of genomes. He observed that rather than adhering to a rigid plan, the genomes of many organisms, like maize and humans, comprise mobile, gene-coding DNA elements. Dooner saw these as small islands of gene-coding regions in a vas...First research to show that diabetes damages DNA in men's sperm and may affect fertility
... sperm DNA damage in diabetic men. From a clinical perspective this is important, particularly given the overwhelming evidence that sperm DNA damage impairs male fertility and reproductive health. Other studies have already shown that, while the female egg has a limited ability to repair damaged sperm DNA, fragm...Oxford physiology professor earns APS' Walter B. Cannon Award
... lives and that of their parents. Physiology in perspective at 120th Annual Meeting in Washington The American Physiological Society (APS) will present its highest award, the Walter B. Cannon Award, to Dr. Ashcroft. She will be the 25th recipient of the Cannon Award, which goes to an outstanding scientist, a...