Commandeering cellular machinery: recognition mechanism to detect small molecules
...to new methods for producing enzymes and important pharmaceutical compounds. "We are hijacking these nuclear recepto...5. (LG335 is structurally similar to Targretin, a pharmaceutical developed to bind RXR. However, LG335 does not effectively bind unmodified RXR.) Though the goal wa......gether, this information may ultimately help guide pharmaceutical companies to develop drugs that specifically target the underlying causes of autism and not just the behavioral symptoms." Daniel Buxhoeveden, PhD, of the University of South Carolina looked for differences in the organization of neur...NSF gives 'teeth' to biomaterials research
...nderson, develops new materials into products with pharmaceutical and bioengineering applications. They license the new product to other companies, which could potentially attract new businesses or support start-up endeavors in the Upstate. A recent study by professor Michael Porter of Harvard University, which was...Common household fragrances may be harming aquatic wildlife, study finds
...ars ago in Japan and Europe. "They were picking up pharmaceutical and personal care products in the wastewater flowing into rivers," Epel said. "In Japan they found them in mussels and fish and discovered they are somewhat persistent they don't break down." Pharmaceuticals, such as estrogens, antibiotics and anti...Tufts Veterinary School scientists decode Cryptosporidium genome
...nd enable us to develop preventive vaccines and/or pharmaceutical treatments," said Saul Tzipori, PhD, director of Tufts' Division of Infectious Diseases and a member of the multi-institutional team researching the genome. Present in drinking and recreational water throughout the world, Cryptosporidium causes w...Trojan-horse therapy blocks buildup of Alzheimer's plaque
...alled A peptide. "There have been many attempts by pharmaceutical companies to develop A peptide inhibitors -- mainl...ying the linker molecules, they could optimize the pharmaceutical properties of the Trojan horse assemblage for example, its ability to penetrate the cell membrane t...Safety and immunogenicity data available for new pertussis booster vaccine candidate for adolescents
...N.C., is one of the world's leading research-based pharmaceutical and healthcare companies and is committed to improving the quality of human life by enabling people to do more, feel better and live longer....OneWorld Health presents preliminary clinical trial results at ASTMH
...Institute for OneWorld Health, the first nonprofit pharmaceutical company in the U.S. The results will be made at the American Society of Tropical Medicine and Hygiene conference to be held Nov. 7-11 at the Fontainebleau Hilton Resort in Miami. Executives from OneWorld Health will also appear on numerous panels a...A new target for control of obesity
...s show that Shp2 has potential of becoming a novel pharmaceutical target for treatment of individuals suffering obesity and leptin resistance. In 2003, the World Health Organization identified obesity as a growing global threat affecting more than 300 million people worldwide. Although it is commonly believed ...OneWorld Health named business leader in public health on '2004 Scientific American 50'
... "Through the unique business model of a nonprofit pharmaceutical company, we are able to target diseases of the poorest people in the world, where the development of new medicines is clearly not profitable. By creating collaborative partnerships among industry, academia, foundations, and the nonprofit sectors, we...MIDI, Inc receives Official Methods(SM) status for the confirmatory ID of the anthrax pathogen
...itary, state laboratories, research facilities and pharmaceutical companies since 1985. In addition to the Sherlock Microbial Identification System, MIDI markets the Sherlock Mycobacteria Identification System for identification of the tuberculosis pathogen and related bacteria. About USAMRIID USAMRIID, locate...Seeking better cancer treatments
...rged an eight-year partnership between the leading pharmaceutical company in steroid hormones (Schering, Germany) and IBET. "Schering has had an extremely fruitful collaboration with Professor Carrondo and her group for many years. It is this exchange of expertise and ideas between two organisations which leads to...Ubiquitination in real-time: A world first at the Universit de Montral
...ts health implications." Medical and pharmaceutical applications In recent years Professor Bouvier a...ubiquitination process. These receptors have great pharmaceutical importance, as they are acted upon by more than half of the prescription medications currently being...Studies suggest promising new directions for gallstone treatment
...mical that switches on FXR. GW4064 is owned by the pharmaceutical company GlaxoSmithKline. Mangelsdorf said the comp...pound, said Mangelsdorf, "I have no doubt that the pharmaceutical industry will use these findings as a basis for commercial drug development, provided there are no s...Science survey ranks top biopharma employers
...parated for scientists employed in the biotech and pharmaceutical industries (n=698) and for academics and consultants to the biotech and pharmaceutical industries (n=464). Survey responses were analyzed by Senn-Delany Culture Diagnostics and Measuremen...INEEL honors five scientists as Laboratory Fellows
...le for establishing industrywide standards for the pharmaceutical and cosmetic industries. For eight years, he served on the organizing committee for the annual Symposium on Biotechnology for Fuels and Chemicals. Apel has been very active in mentoring junior and mid-level INEEL scientific staff, and frequen...Yale and Pfizer launch visiting professorship pilot program
...ts more effectively on career opportunities in the pharmaceutical industry. This novel visiting professorship program was developed and sponsored by Pfizer's Discovery Laboratories in Groton, the Women Leaders Network at Pfizer and the Office for Women in Medicine at Yale. The first visiting professorship ha...$43 million from Gates Foundation to produce inexpensive antimalarial drug for Third World
...Institute for OneWorld Health, the first nonprofit pharmaceutical company in the United States, will create a powerf...our groundbreaking technology on producing a known pharmaceutical -- the most effective antimalarial out there -- so that it reaches the people who need it most. Thi...Science's Breakthrough of the Year: Salty, acidic soup could have supported life on Mars
...entures by foundations, rich countries, academics, pharmaceutical companies and other groups were behind several prominent initiatives this year, including a malaria vaccine trial and efforts to provide anti-HIV drugs. Genes in a Drop of Water: In 2004, researchers hit on a new way to identify life forms too smal...NJIT professor discovers new mixing method for microchip-sized labs
...o have many useful applications, especially in the pharmaceutical industry. "The process will be useful in the preliminary phases of drug discovery," she said, "where reagents need to be well-mixed to produce purer test drugs with fewer unwanted by-products." Her process will also help engineers design smaller, mo...