American Chemical Society's Weekly PressPac -- Aug. 8, 2007
...ce, become a new generation of imaging agents that pinpoint the location of diseased tissue in the body. However, the question of whether these nanomaterials are toxic to living cells or organisms has not been fully answered, the researchers explain. The scientists used laboratory tests on human lung cells ...Role of thyroid hormones in slumber under investigation at Rutgers
...ndation, a team of Rutgers-Camden researchers will pinpoint precisely how and when thyroid hormones influence the brains sleep-related structures. Findings could yield new knowledge on a previously unknown sleep-regulatory substance and potentially answer why existing sleep medications arent the cure-all for ...News tips from ACS Chemical Biology
...led the double barrel shotgun approach that helps pinpoint key cellular proteins How tricking cells with a mimic of a chemically modified protein can help identify components of cell signaling pathways. http://www.eurekalert.org/jrnls/acs/index.php?page=chemicalbiology ...Risk genes for multiple sclerosis uncovered
... National MS Society, is that it is helping us to pinpoint genes that may elevate the risk of developing MS and other autoimmune diseases, pointing the way to new areas of research and new therapeutic targets to both treat and eventually prevent these diseases. This study illustrates the power of collabora...New research identifies anti-viral protein that may predict who might be at risk to develop lupus
... levels of interferon-alpha will also help them to pinpoint the other factors, including the relevant genetic variations that determine why one family member develops the disease while another doesnt. The hope is that we may be able to use interferon-alpha levels as a measurement to predict who might be at ......uters' are diffuse within the cell. Yet these must pinpoint and then bind to specific counterparts while swimming in the cells thick, erratic molecular stew something like finding a friend in a Tokyo subway station during rush hour. In the classical view of molecular recognition, the binding molecules fi...Genomic analysis uncovers new targets for HIV vaccine
... will be a series of future genome-wide studies to pinpoint additional targets for HIV vaccines. In the new analysis, patients with specific gene variants in key immune system cells appear to be much better at controlling the proliferation of the virus after infection. These gene variants are known as polymor...First genome-wide study of infectious disease opens new avenues for HIV treatment, vaccines
...e period soon after infection. If scientists could pinpoint the gene variants that help some people control HI...ntly building on these studies of polymorphisms to pinpoint the specific human gene variants that influence HIV replication. We applaud the CHAVI investigator...Species detectives track unseen evolution
...ched the Zoological Record database (1978-2006) to pinpoint reports of hidden (cryptic) species both biogeographically and taxonomically, and found 2207 examples. Pfenninger and Schwenk, who are from Germany based at J.W. Goethe-Universitt in Frankfurt found evidence for cryptic species evenly spread among al...Gene discovered for type 1 diabetes in children
...ed juvenile diabetes. As investigators continue to pinpoint genes contributing to diabetes, they have their eyes on providing a scientific basis for designing better treatments and preventive measures for the disease. The research adds a new gene and new knowledge to the four genes previously discovered for...Common environmental chemicals in diet affect fetal ovarian development
...hat their Wellcome Trust-funded study will help to pinpoint the stages of pregnancy at which the developing fetus is most sensitive to disruption and also to measure the degree to which fertility is affected in the offspring after puberty, following their exposure as fetuses to environmental concentrations of...Gene variations directly link inflammation to an increased risk for lung cancer
...n Association for Cancer Research, is the first to pinpoint the mechanism by which damage to the lung might trigger an overzealous inflammatory response by the immune system, leading to lung cancer. The variants, or polymorphisms, were found in genes for interleukin 1A and interleukin 1B, two signaling mole...Early fire risk for mountains near Los Angeles
... The researchers plan to refine their technique to pinpoint a single high fire-risk threshold between 77 percent and 71 percent foliage moisture. The uncertainty is caused by the one large fire that ignited when foliage moisture was 77 percent. Dennison says researchers who conducted a 2006 study found tha...Rutgers, Penn researchers capture research dollars to improve prostate cancer diagnostic methods
...rostate glands. The innovative techniques also can pinpoint concentrations of suspicious tissue, thus improving the accuracy of a biopsy and, if needed, the effectiveness of treatment. Two recent grants totaling $492,000 from the National Institutes of Health, a $50,000 grant from the New Jersey Commission ...News tips from the Journal of Neuroscience
...e Charpier In this weeks Journal , Polack et al. pinpoint the origin of seizure activity in Genetic Absence Epilepsy Rats from Strasbourg (GAERS). Absence seizures such as childhood absence or petit mal are typically considered as arising without a seizure focus, i.e., a highly circumscribed area from which......archers used a line of genetically altered mice to pinpoint how the dentate gyrus contributes to the kind of pattern separation involved in identifying new and old spaces. Whilst the mice behaved normally in most situations, they became confused when required to discriminate between different spaces. This m...New bacterium discovered -- related to cause of trench fever
...t drugs, so it is essential to explore further and pinpoint which one is involved. The cat scratch bacteria and the one that brought down soldiers and AIDS patients can be reined in with the same antibiotic, but the Peruvian microbe is usually countered with different antibiotics, Koehler says. Also, careg...NIAID supports research into etiology of fungal-induced inflammation in chronic sinusitis
...nt will allow Dr. Kita and Dr. Lawrence to further pinpoint the mechanism by which the fungus causes the inflammation, and specifically what fungal products are involved. Both are important milestones to deepen our understanding about CS, and will help us to better understand the mechanism of action of newer...Getting to the core of an emergent public health threat
...sights into coronavirus biology that may also help pinpoint future weaknesses in the viral armament. In a recent paper published in the Journal of Virology (March 2007), "Mouse Hepatitis Coronavirus A59 Nucleocapsid Protein Is a Type I Interferon Antagonist," lead authors Ye Ye and Kevin Hauns, graduate stude...... we could only ask qualitatively." Being able to pinpoint just how different the mutants are is valuable, said Theriot, because they often are less infectious than normal Listeria. Once Listeria invades a host cell, it uses the actin mechanism to move from cell to cell, never again exposing itself to the or...