Tag: "pinpointed" at biology news

Customized gene chip provides rapid detection of genetic changes in children's cancer

... cancer to overtreatment. Cancer researchers have pinpointed specific genetic abnormalities that influence the aggressiveness of neuroblastoma. An important abnormality is loss of heterozygosity (LOH), the deletion of one copy of a pair of genes. When the gene involved is a tumor suppressor gene, LOH removes a...

Understanding Fragile X syndrome with the blink of an eye

...Erasmus University Rotterdam report that they have pinpointed a specific cause of defects in motor learning in Fragile X patients. Their work represents the first investigation of the role of abnormalities in the brain's cerebellum in Fragile X syndrome. Fragile X syndrome is caused by a defect in the Fragile X...

Gambling monkeys give insight into neural machinery of risk

...uke University Medical Center neurobiologists have pinpointed circuitry in the brains of monkeys that assesses the level of risk in a given action. Their findings -- gained from experiments in which they gave the monkeys a chance to gamble to receive juice rewards -- could give insights into why humans compulsi...

Anthrax stops body from fighting back, study shows

...er due to quick communication from the doctors who pinpointed the first anthrax infection, Southwick said. Twelve other people contracted cutaneous (skin) anthrax infections, which are not usually fatal. Knowledge about anthrax and how it works has improved since then, too, Hanna said. Now doctors know what an...

U-M researchers identify new blood test for prostate cancer

...row the field to the 22 biomarkers that most often pinpointed the cancerous blood samples. More than 230,000 men will be diagnosed with prostate cancer this year. Current screening methods involve a blood test to check for prostate specific antigen, an enzyme produced by the prostate. But the PSA test is contr...

Delving deeper into the machinery of cocaine addiction

...iversity of Texas Southwestern Medical Center have pinpointed a key molecular mechanism by which genes are switched on in the brain that govern both short-term and long-term effects of cocaine. Such activation is called transcriptional activation because it induces the gene to begin making copies of itself into...

Wnt signaling controls the fate of stem cells in adult brains

...he Scientific Director of Cure Autism Now, finally pinpointed Wnt3 as the persuasive signal molecule secreted by the astrocytes. Wnt proteins form a family of highly conserved signaling molecules that play a crucial role in controlling cell expansion and lineage decisions in many types of stem cells. "We bl...

ECCO 13 evidence suggests link between Chlamydia and OAL

...erence (ECCO). Several infectious agents have been pinpointed as potential risk factors for lymphoma development. Members of the Chlamydia genus of bacteria, in particular, may play a role in tumour development through their involvement in a wide spectrum of human diseases that cause persistent infections. A we...

Scientists crack code for motor neuron wiring

...code. Using these antibodies, Dasen and colleagues pinpointed the pattern of expression of each protein within the set of motor neurons that project to limb muscles. "Once we had these reagents, we were able to obtain the high resolution maps of Hox expression that were necessary to address more complex aspects...

Polymer gel can block toxic leakage problem in gene therapy

... would believe this was happening." The study also pinpointed the routes for the viral escapes. Those particles were escaping from the tumor area into the bloodstream through rifts in tiny tumor blood vessels created by damage from the injection needle. Yuan said such viral escapes are inevitable since the need...

Figuring out the ups and downsand sidewaysof neural development

...issue of Neuron, Mihaela igman and colleagues have pinpointed a key regulator of spindle orientation in mammals. They drew on discoveries made in the fruit fly Drosophila, in which other researchers had found a gene called Inscuteable to be a central controller of spindle orientation. Analyzing genetic database...

Dog genome sequence and analysis published in Nature

...ray wolf and coyote. By comparing these dogs, they pinpointed ~2.5 million individual genetic differences among breeds, called single nucleotide polymorphisms (SNPs), which serve as recognizable signposts that can be used to locate the genetic contributions to physical and behavioral traits, as well as disease....

Researchers publish dog genome sequence

...g the gray wolf and coyote. In this sampling, they pinpointed tiny spots of genetic variation, called single nucleotide polymorphisms (SNPs), which serve as recognizable signposts that can be used to locate the causes of genetic disease. "Of the more than 5,500 mammals living today, dogs are arguably the most r...

Brain's own cannabis compound protects against inflammation

... experiments by Oliver Ullrich and colleagues have pinpointed how one of the brain's endocannabinoids protects neurons from inflammation after such damage. They say their studies could lead to new drugs to treat the inflammation and brain degeneration from MS or other such disorders. In an article in the Januar...

Darkness unveils vital metabolic fuel switch between sugar and fat

...type 2 diabetes research. A series of experiments pinpointed 5-prime adenosine monophosphate (5'-AMP) as the key molecular mediator of the constant darkness effect, switching mice from a glucose-burning, fat-storing state to a fat-burning, glucose-conserving lethargy. Active mammals a bear foraging for food ...

Scientists link another gene to degenerative blindness

...ant. Subsequent DNA sequencing of that target area pinpointed calnexin as the culprit gene, explains lead author Erica Rosenbaum, a researcher in Colley's laboratory. Colley plans to continue searching for other genetic mutations that might help trigger retinal degeneration. "The more mutations we identify the ...

Mining for gems in the fungal genome

...t pathology and medical microbiology Nancy Keller, pinpointed the genes responsible for creating dozens of secondary metabolites, a class of compounds that make good drug candidates. Already, analysis of one subset of these genes has revealed that they encode proteins required to produce an anti-tumor agent. ...

New genetic discovery explains 74 percent cases of age-related macular degeneration

...atistically and genetically but, most importantly, pinpointed the biological origin of the disease," added Dr. Allikmets. "In just a few short years, we've gone from knowing very little about what causes AMD to knowing quite a lot. We now have clear targets for early therapeutic intervention." Though the new...

Novel method reveals how menthol discovery could point towards new or improved pain therapies

...se functioning normally. The scientists' analysis pinpointed a potential interaction site for menthol, as well as a site that translates binding information to ion channel activity. Ion channels are proteins found in the cell membrane that can form a tunnel or channel that allows specific ions to move across...

Scientists reveal how deadly toxin hijacks cells

MADISON - Scientists have pinpointed exactly how botulinum neurotoxin A - a potential agent of biological warfare and one of the most lethal toxins known to man - is able to sneak into cells. The finding is crucial for the development of new treatments against botulism, a paralytic ill...

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(Date:10/17/2014)... is critical and pertinent for practicing physicians and clinicians ... epidemic. The Journal, Disaster Medicine and Public Health ... and Public Health, to surround the public, medical professionals ... moment. , On October 17, the journal published ... primer was prepared by Dr. Eric Toner, internist and ...
(Date:10/16/2014)... the human body. Battles are won, lost or ... this stalemate—known as tumor dormancy—can last up to ... that is poorly understood. , A new ... Torquato, a Professor of Chemistry at Princeton University, ... and the switch to a malignant state. Published ...
(Date:10/16/2014)... can be cultivated efficiently, they are anything but ... by monoculture cultivation is becoming increasingly evident. Despite ... form and are regarded as the sole possibility ... quite wrongfully, finds Bernhard Schmid, an ecology professor ... novel form of agriculture and forestry. After all, ...
Breaking Biology News(10 mins):Modeling tumor dormancy 2Plant communities produce greater yield than monocultures 2Plant communities produce greater yield than monocultures 3
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