European Science Foundation's Forward Look reaches out beyond the endless frontiers
...eart is food security in which food systems play a pivotal role. Food systems not only contribute to providing safe and healthy food; in a broader context they also contribute to an increasing number of environmental and societal goals. This Forward Look will develop appropriate scenarios based on the desire...Cornell scientists link E. coli bacteria to Crohn's disease
...gut bacteria have long been suspected in playing a pivotal role in the development of Crohns disease, but the specific bacterial characteristics that drive the inflammatory response have remained elusive. Researchers at Cornell examined possible causes for the disease in patients with Crohns restricted to t...How a pain in the neck could be bad for your blood pressure
...s tractus solitarius, an area of the brain that is pivotal in control of autonomic functions - body functions under unconscious control. They propose that nervous signals from the neck could play a key role in ensuring that adequate blood supply is maintained to the brain as we change posture, such as from l...New proteomics research promises to revolutionize biomedical discovery
...lates the stability of small RNA molecules playing pivotal roles in cell function and regulation. The existence and importance of this enzyme was recognized for more than a decade, but it had been so far impossible to isolate it in the sea of proteins that make up human cells and further characterize it. We ...Researchers probe risks, benefits of folic acid fortification
...fect with folic acid fortification. First, folates pivotal role in DNA synthesis also makes it a potential growth factor for cancerous or pre-cancerous cells, and when administered in large quantities to individuals who unknowingly harbor cancer cells, it could paradoxically enhance cancer development. The a...Tracing Parkinson's lethal mechanism
...monstrated that the action of Cdk5 on Prx2 plays a pivotal role in the neuronal damage from MPTP. Importantly, the researchers discovered evidence that the loss of Prx2 activity also plays a role in human PD. They found reduced Prx2 activity in brain tissue from PD patients. These findings provide a mech...Biovest announces interim blinded data of fast-tracked pivotal Phase 3 clinical trial of BiovaxID
...ed interim data from the start of its fast-tracked pivotal Phase 3 clinical trial of BiovaxID for Non-Hodgkin...ancer vaccine undergoing testing in a Fast-Tracked pivotal Phase 3 clinical trial for a target indication of Non-Hodgkins Lymphoma. BiovaxID is a personalized...Interim analysis of anti-cancer vaccine, BiovaxID, to be conducted
...ID. BiovaxID is an anti-cancer vaccine that is in pivotal Phase 3 Clinical Trial for the indication of non-H...le safety concerns in the current BiovaxID Phase 3 pivotal Clinical Trial at this time in our data review. To facilitate Biovests regulatory agency discussion...Smithsonian scientists connect climate change, origins of agriculture in Mexico
...vidence from Mexicos Central Balsas valley links a pivotal cultural shift, crop domestication in the New World, to local and regional environmental history. Agriculture in the Balsas valley originated and diversified during the warm, wet, postglacial period following the much cooler and drier climate in the ...Cytomegalovirus exacerbates atherosclerosis through an autoimmune mechanism
...nstitute G. Gaslini in Genova, Italy, confirms the pivotal role played by Cytomegalovirus infection in the pa...on and high cholesterol levels are known to play a pivotal role in the pathogenesis of the disease that also recognises a genetic influence. However, it is wel...Plants tag insect herbivores with an alarm
...d an 11 amino acid peptide, inceptin, that plays a pivotal warning role in cowpea plants being attacked by the fall armyworm. Inceptin is part of a larger, essential enzyme, chloroplastic ATP synthase, in plants. When the fall armyworm feeds on cowpea, the insect ingests ATP synthase and breaks it down, rele...Enhanced MR-guided focused ultrasound guidelines demonstrate improved efficacy and durability
...reater symptom relief than those treated under the pivotal study guidelines. The symptom severity score (SSS)...atment guidelines and 71% of patients treated with pivotal guidelines. Expanded and commercial treatment guidelines resulted in greater reduction in sympt...Einstein's Dr. Vern Schramm elected to the National Academy of Sciences
...treating T-cell malignancies. It is currently in a pivotal phase IIb clinical trial (specifically targeted to study efficacy) at sites in the U.S., eastern and western Europe, and South America. Another transition-state inhibitor developed by Dr. Schramm is now being studied as a possible treatment for au...BCM, Rice make major advance in structural biology
...gets to witness a success like this one, which was pivotal not only for myself and my students but also for every other scientist in this field." "We can use this method to improve many other systems in our lab." Ma said "We are indeed working on a bunch of other important systems, such as membrane protein...BDSI announces positive phase III clinical trial results
...l in cancer patients with breakthrough pain in its pivotal Phase III efficacy clinical trial for the product....d our entire BEMA Fentanyl team for achieving this pivotal milestone in the history of BDSI" said Frank E. ODonnell Jr., M.D., Chairman of the Board of BDSI. ...Scripps research study shows humans and plants share common regulatory pathway
...milarities between the Nod1 protein, which plays a pivotal role in the innate immune systems recognition and response to bacterial infection and members of the R protein family. "There has been a great deal of speculation that R proteins and Nod1 are related, but our study provides the first direct link b...Donald Metcalf receives American Association for Cancer Research Lifetime Achievement Award
...therapeutic use. Dr. Metcalfs work provided the pivotal demonstration that CSFs, when injected into animals, stimulated the formation and regulated the activity of white blood cells. Exploiting this, his collaborators documented the effectiveness of GM-CSF and G-CSF (two primary white blood cell regulator...Darwin's famous finches and Venter's marine microbes
...CA -- Although the Galpagos finches were to play a pivotal role in the inception of Darwins theory of evolution through natural selection, he had no inkling of their significance when he collected them during his voyage on the HMS Beagle. Similarly, it is hard to predict the impact the vast amount of mari...Largest-ever search for autism genes reveals new clues
...ulty wiring, a genetic blueprint gone awry in this pivotal neurotransmitter system is a prime suspect. Some key genes associated with the glutamate system are located in chromosome regions previously associated with autism, note the researchers. Previous studies have also linked abnormal glutamate functio......duction in p-tau levels. The findings point to a pivotal role for Hsp90 in aberrant tau degradation and potentially in tau refolding. Unlike many drugs, EC102 is able to cross the blood-brain barrier, making it a highly promising therapeutic candidate for AD and other conditions in which tau accumulates in...