Tag: "pivotal" at biology news

First big influenza genome study reveals flu evolution

...hput influenza genome sequencing pipeline offers a pivotal strategy for crafting emerging vaccines that work. "Right in the middle of flu season, we could determine which influenza strains are present in the population, which ones are dominant, and how well a given vaccine works," Ghedin notes. She adds that...

Studying climate change in the Arctic: Scientists and students working together

...ers at the study sites will come to appreciate the pivotal role "their" rivers play in the Arctic System. The data generated will greatly advance scientific understanding, but a final objective to excite kids about science is perhaps most important because it is an essential step for creating the next gene...

Neurologix announces positive results of gene therapy clinical trial in Parkinson's disease

...logix intends to formulate and submit to the FDA a pivotal trial protocol for the use of STN AAV-GAD in the t...ted side of the brain. We look forward, now, to a pivotal trial to even more vigorously test and corroborate these important results." About the Neurologix P...

New insights into the software of life

...ollaboration, particularly David Hume who has been pivotal in developing the IMB's partnership with RIKEN over several years." As part of the collaboration with RIKEN, Professor Hume's group has recently been awarded a grant from RIKEN to continue the translation of this work into the next phase, the Human ...

Scientists determine structure of enzyme that disrupts bacterial virulence

...t 3-dimensional structure of an enzyme that may be pivotal in preventing certain bacterial infections in plants, animals and humans, according to a study published in the Proceedings of the National Academy of Sciences. The enzyme had already been shown in previous studies to significantly decrease soft rot...

Career prospects in Germany

...an researchers working in the United States play a pivotal role in establishing transatlantic networks and exchanging information between Europe and the US. The San Diego meeting marks the fourth conference held by the German funding organisations to provide support to and facilitate networking between Germa...

New advance in prostate cancer management

...the cancer's aggressiveness. The technique will be pivotal in developing a test for prostate cancer aggressiveness which may ultimately prevent thousands of men undergoing unnecessary surgery, with its often associated severe side effects including incontinence and impotence. "This represents a real advance...

Certolizumab pegol demonstrates positive results in two Phase III Crohn's disease trials

...- UCB today announced positive results for the two pivotal Phase III trials (PRECISE 1 and 2) of certolizumab pegol (CDP870) in the induction and maintenance of clinical response in moderate to severe active Crohn' TM s disease. The PRECiSE trials assessed the safety and efficacy of CIMZIATM compared to pla...

Evolution of taste receptor may have shaped human sensitivity to toxic compounds

...unds found in nature. The work strongly supports a pivotal role for bitter-taste perception in toxin avoidance in humans, an attribute that could have come into particular play during periods of expansion into new environments. More broadly, the work contributes to the debate on the mechanisms governing the ...

Molecular steps involved in the creation of gene-silencing microRNAs identified

...emarkably powerful molecules that appear to play a pivotal role in gene silencing, one of the body's main strategies for regulating its genome. A scant 22 nucleotides in length, miRNAs appear to work by binding to and somehow interfering with messenger RNA, itself responsible for translating genes into prote...

SEROQUEL: An effective treatment option for aggression in patients with schizophrenia

...oday, an analysis of pooled data from these three pivotal trials, included a total of 389 patients who exhibited aggressive behaviour at study entry. The results show that patients who received SEROQUEL demonstrated significantly greater improvements in symptoms of aggression and hostility, compared with pa...

Gene controlling circadian rhythms linked to drug addiction, UT Southwestern researchers find

... the body's main biological clocks also may play a pivotal role in drug addiction, researchers at UT Southwestern Medical Center have found. The Clock gene not only controls the body's circadian rhythms, including sleep and wakefulness, body temperature, hormone levels, blood pressure and heart activity, it...

Brain networks change according to cognitive task

...fic regions. This finding suggests the IFG plays a pivotal role in "making" task specific regions more or less sensitive, depending on the task. "Previous studies showed that the IFG is active in many different language tasks and suggested that the IFG was involved not only in the integration process but al...

New findings in taste and smell research

...oductive strategies. Sperm chemoattractants play a pivotal role in fertilization through mediating sperm-egg interactions and increasing gamete encounters. Surprisingly, no study has examined the influence of these signals under realistic conditions. Ubiquitous for all organisms is the presence of fluid moti...

Oceans more vulnerable to agricultural runoff than previously thought, study finds

...cultural runoff from the Mississippi River plays a pivotal role in creating this annual dead zone, which measured 8,500 square miles (22,000 square kilometers) in 2002-an area bigger than the state of Massachusetts. "In the Gulf of Mexico, there's the possibility that hypoxia could occur at a local scale, wh...

Pro-inflammatory enzyme linked to diabetes; Immune system's macrophages may be key to treatment

...glucose metabolism, and in systemic myeloid cells, pivotal players in inflammatory responses as they produce macrophages. In response to challenges with a high-fat diet, mice with Ikk- deficient myeloid cells retained insulin sensitivity in all target tissues. Because the myeloid cells (and their macropha...

FDA approves ABRAXANE(TM) for metastatic breast cancer

...r Program at Northwestern Memorial Hospital. "The pivotal clinical trial results demonstrated that ABRAXANE ...persensitivity, ABRAXANE was well tolerated in the pivotal Phase III trial. Neutropenia (all grades) was experienced by 80% of patients treated with ABRAXAN...

First 'atlas' of key brain genes could speed research on cancer, neurological diseases

...activity, of "target" genes. These factors play a pivotal role in brain development by direction the formation of neurons and supporting cells called glia from uncommitted progenitor cells. Until now, brain transcription factors had not been systematically isolated and their locations within different parts...

National Evolutionary Synthesis Center launches in Durham, North Carolina

...rative, cross-disciplinary studies. It will play a pivotal role in the further unification of the biological sciences as it draws together knowledge from disparate biological fields to increase our general understanding of biological design and function. Finally, the center will play a critical role in organ...

Chromosome 16 publication fulfills DOE's human genome commitment

...and a thrill to the DOE team to have played such a pivotal role in the launching and successful completion of this most noble of human undertakings." Chromosome 16 was the original focus of DNA repair gene studies initiated at DOE's Los Alamos National Laboratory in 1988. Additional interest stemmed from the...

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(Date:11/7/2014)...  In conjunction with the Glendale ... Foundation of the Verdugos has announced the " GLENDALE ... $250,000 initiative to keep the Verdugo Regional Crime Lab operational ... months of existence, the Lab has processed more than 400 ... enforcement. "Because our number one priority is the ...
(Date:11/6/2014)... - Insilico Medicine, Inc, a Baltimore-based bioinformatics company ... diseases announced a research collaboration with the international ... Inc (OTC: CSBR). , "There are many companies ... Champions Oncology,s TumorGraft technology is unique in a ... experimentally generating vast amounts of valuable data. Our ...
(Date:11/4/2014)... of death at the right time might actually help ... that could help in understanding animal populations, pest control ... paper in the journal Trends in Ecology and ... conclude that the kind of positive population effect an ... mortality, depends on the size and developmental stage of ...
Breaking Biology News(10 mins):Community Foundation Of The Verdugos Unveils Campaign To Fund Glendale-Burbank DNA Justice Project 2Insilico Medicine, Inc announces research collaboration with Champions Oncology, Inc 2When less is more: Death in moderation boosts population density in nature 2
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