Tag: "plaque" at biology news

Anti-cholesterol drug treats Alzheimer's disease in mice

...cally reduces the levels of brain-clogging amyloid plaque in mice engineered to have a human form of the amy...lled A peptide, the building block for the amyloid plaque that clogs the brain in Alzheimer's disease, ultimately killing brain cells.In the mouse experiments...

Experimental lupus drug may also work against atherosclerosis

... atherosclerotic deposit in a way that may lead to plaque stability, so pieces don't break off so easily. The breaking off of plaques, which then can lodge elsewhere in already narrowed arteries, is a key mechanism for heart attacks and strokes. Mishra got similar results when ...

Gene linked to greater risk of heart disease in type 2 diabetes

...ing to atherosclerosis -- the dangerous buildup of plaque that can lead to partial or complete blockage of the artery, leading to heart attack or stroke. In the first part of this study, the researchers mapped the structure of the CD36 gene, which consists of hundreds of nucleic acids strung together like b...

New source for heart bypass replacement blood vessels: Fibrin-based TEVs

...-diameter grafts usually failed due to thrombus or plaque formation. Various tissue-engineering approaches were developed using natural or synthetic biomaterials as scaffolds for cell growth. Biodegradable scaffolds using polyglycolic acid (PGA) have shown promise and collagen gels also worked, though 7mm c...

Nuclear imaging offers possibility for early detection of patients with coronary heart disease

...isease) and, more specifically, the composition of plaque build up that can block the flow of blood through ...blockage in some coronary arteries caused by fatty plaque accumulated over the years, the authors of "Molecular and Metabolic Imaging of Atherosclerosis" poin...

New findings in innate immunity may lead to treatments for atherosclerosis

...o prevent excessive inflammation and contribute to plaque stability. Indeed, patients with higher IL-10 serum levels have a better chance of recovery. Therefore, elevated IRAK1 modification and IL-10 levels observed in atherosclerosis patients may be a compensatory and self-protective mechanism." Manipulati...

Fewer calories may slow Alzheimer's

... diet-restricted mice, both the amount and size of plaque wasabout 50 percent less than in mice that ate as much as they wanted. "The power of this study is that two different sets of [human] familymutations were equally sensitive to the effect of diet and slowing theAlzheimer's-like change," said Fin...

Gene vaccine for Alzheimer's disease shows promising results

... protein vaccination had shown some slowing in the plaque buildup, negative side effects also occurred in a ..., immunization with amyloids slowed the buildup of plaque on the brain and appeared to slow cognitive loss. "Although human clinical trials are still at leas...

Reduced calorie and carbohydrate diet slows progression of Alzheimer's disease in mouse model

...to developthe disease. The diet eliminated amyloid plaque development, which isthe underlying pathology in A...e fed ad-libitum, 100% developed these plaques. No plaque development was detected in the mice fed a carbohydrate and calorie restricted diet. The diet regim...

Mouse brain cells rapidly recover after Alzheimer's plaques are cleared

...t, Holtzman and some other scientists had regarded plaque damage to nerve cells as a fait accompli--somethin...ell branches. To correlate brain cell changes with plaque development, Brendza injected another dye, developed by scientists at the University of Pittsburgh, ...

Progress toward a more targeted treatment of Alzheimer's disease

...-secretase Alzheimer's disease involves a kind of plaque that forms in the brain cells. Several years ago, ... where it has already developed, and by preventing plaque from forming in the parts of the brain they have not yet affected."...

Study finds direct association between cardiovascular disease and periodontal bacteria

...x and colleagues collected on average seven dental plaque samples from a total of 657 older adults enrolled in INVEST who had not lost their teeth. The samples, taken from predetermined sites in the mouth, both diseased and healthy, were measured for 11 oral bacteria, including four bacteria widely regarde...

Anita Roberts to deliver Excellence in Science lecture

..., complimentary registration at the meeting, and a plaque in recognition of the award....

Neuronal 'traffic jam' marks early Alzheimer's disease

...of Alzheimer's disease early in their life, before plaque formation, to see if we could detect early evidenc...ly in the life of those animals -- well before any plaque deposition -- were obvious axonal defects," said Goldstein. "We saw large swellings in their axons. ...

William C. Rose Award lecture will focus on cytochrome P450

...r, and Rowena G. Matthews. The Award consists of a plaque and transportation and expenses to present a lecture at the ASBMB Annual Meeting. In nominating Dr. Guengerich for the Award, Dr. Minor J. Coon, of the University of Michigan Medical Center, recalled, "Fred joined my laboratory as a Postdoctoral Fell...

To control germs, scientists deploy tiny agents provocateurs

...ealth. Biofilms form the green slime on rocks, the plaque on human teeth and the slippery film on ship hulls. If a single cell were analogous to one man, biofilms would be the "bacterial equivalent of mob mentality," says Blackwell. In the realm of health, biofilms are at the root of growing numbers of ten...

Molecule that usually protects infection-fighting cells may cause plaque deposits inside arteries

... normal AIM function, there was marked presence of plaque deposits in the arteries following a diet of high-... an artery and gradually thicken into a plaque. As plaque grows, it narrows the artery more and more. When the plaque ruptures, blood clots form that can bloc...

UC Davis researchers discover new link between C-reactive protein, and heart disease and stroke

...e protein, a key finding that helps to explain how plaque formation is initiated. This is particularly impor...is tells us that there is cross-talk in the active plaque where these cells act in concert to cause very high C-reactive protein levels in the atheroma, which...

Leslie Roberts of Science wins ASM Public Communications Award

...ublic understanding of microbiology, consists of a plaque and $2,500 cash prize. It will be presented this year in Atlanta on June 6 during the General Meeting of the American Society for Microbiology. Judges called Roberts' story "first-rate reporting," "an important story meticulously researched and beaut...

Leslie Roberts, Science Deputy News Editor, wins prize for 'first-rate' polio story

... promoting public understanding of microbiology. A plaque and a $2,500 cash prize will be presented to Roberts in Atlanta on 6 June during the ASM's General Meeting. Judges for this year's Award were Rick Weiss of the Washington Post; Marilyn Marchione, a medical writer for the Associated Press; and Janet ...

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(Date:7/29/2014)... New research from scientists at the University of Kent ... inside cells are regulated a breakthrough that could ... A team from Kent,s School of Biosciences uncovered the ... within cells known as actin filaments are ... these actin filaments appear to completely stable, providing a ...
(Date:7/29/2014)... breaking new book that brings together two of the ... the profile of insect fossils through stunning photographs and ... and James E Jepson, details the incredible preservation and ... the scene for what these remarkable fossils can tell ... the future of our planet. Like the mosquito in ...
(Date:7/28/2014)... U.S. Food and Drug Administration (FDA) for other purposes ... inside human cells, including those that cause Legionnaires, disease, ... mBio , the online open-access journal of the ... identifying non-antibiotic drugs that could one day help curb ... the list inhibit the growth of at least three ...
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