Tag: "platelets" at biology news

Research aims to identify markers for menopausal women at risk for deadly blood clot

...ler, has developed a novel concept that uses blood platelets to define thrombotic risk. The team is testing its...elet change. The team is examining what happens to platelets in the presence of hormones whether platelet microvesicles occur more frequently as a result, if a ...

American Chemical Society's Weekly PressPac -- July 11, 2007

...lls in the bloodstream. Messaging between RBCs and platelets (blood components that cause clotting) they say, c...oup now has established that the ATP signals blood platelets to produce nitric oxide (NO). That messenger molecule has a variety of functions, including dilating...

JCI table of contents: July 12, 2007

...lot prevention After a blood vessel in injured, platelets cluster together to plug the site of injury in the form of a blood clot (thrombus). In arterial disease, altered platelet aggregation can block blood vessels and cause heart attack or stroke. Platelet aggregation involves the binding of many molecule...

Study advances vCJD prion detection

...n brain tissue extracts prepared from normal human platelets - a type of blood cell essential for clotting. The sample is incubated and exposed to repeated rounds of ultrasound, which break the prions up into more numerous smaller particles. The research was carried out by the University of Edinburgh Nat...

Description of a gene implicated in the development of Fanconi anemia and predisposition to cancer

...ssues, such as the formation of white blood cells, platelets and other elements of the blood (Fanconi D2 patients have a dysfunction in the production of blood in the medulla starting at 2.4 years old on average), neuronal development (89% of the Fanconi D2 patients suffer from microcephalia) or the formation ...

Anthrax paralyzes immune cells with lethal toxin, UF research shows

...w anthrax paralyzes other types of cells, like the platelets that normally help blood clot. "We know that patients with anthrax bleed," Southwick said, adding that victims of inhalational anthrax often suffer hemorrhages in their lungs and lymph nodes. "No one understands why, and it could very well be due t...

Penn scientists engineer small molecules to probe proteins deep inside cell membrane

...lled V3, behaves much like IIb3, in that it causes platelets to stick to certain proteins on the outside of the cell. "We wanted to see if we could differentiate between the two integrins using two different peptides and, in fact, we can," notes co-senior author Joel Bennett, MD, Professor of Medicine, who wo...

Blood's clotting cells harbor 'ticking time bombs,' finding may help extend blood supply

...ns now required. The researchers discovered that platelets characteristically short life span, which for huma... form of suicide called apoptosis. We found that platelets undergo really classical apoptosis, said David Huang of The Walter and Eliza Hall Institute of Medic...

JCI table of contents -- March 22, 2007

...ping bleeding after tissue injury. The adhesion of platelets to a blood vessel wall and their subsequent aggregation and activation are essential for thrombus formation. Previous in vitro studies have shown that a protein known as vWF is essential for platelet adhesion, aggregation, and activation in thrombus ...

Biotechnology Study Center honors Joan V. Ruderman, Salvador Moncada and Charles N. Serhan

...lial cells that relaxes blood vessels and prevents platelets from clumping; its derivatives ameliorate vasospasm and pulmonary hypertension. But perhaps his greatest contribution appeared in Nature (June, 1987): "Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor."...

JCI table of contents -- March 8, 2006

...rg/article.php?id=29176 HEMATOLOGY: SHIP1 in platelets practices first aid Platelets are cell fragment...ry and formed smaller thrombi that contained fewer platelets than normal mice. Consistent with these in vivo studies, when platelets from SHIP1-deficient mice we...

Adult stem cells to repair hearts damaged by severe coronary artery disease investigated

...eople who donate specific blood components such as platelets or red blood cells, to collect from the subjects bloodstream, an enriched preparation of cells that contain CD34+ stem cells. When this process, known as apheresis, is complete, technologists further process the collected stem cells with Baxters ISOL...

MIT: Nanocomposities yield strong, stretchy fibers

... now stronger and tougher. Importantly, the clay platelets are distributed randomly in the material, forming a structure much like the jumble that results when you try to stuff matches back into a matchbox after they have all spilled out. Instead of a neatly packed arrangement, the process results in a very ...

JCI table of contents: December 1, 2006

...acid aspirationinduced ALI. Reducing the number of platelets in the mice or inhibiting the platelet-neutrophil ...xpression of a molecule known as P-selectin by the platelets was crucial for mediating the platelet-neutrophil interaction, which induced platelets to produce pr...

Computing catches up with theory

...with flow made sense. Faster blood flow meant more platelets encountered the clot each second, so more had a ch...m injured tissue or ex-isting thrombi could signal platelets to begin sticking together at the site of the injury. Richardson proposed that a short delay between...

New biologic treatment for tennis elbow may replace surgery for chronic sufferers

...an Journal of Sports Medicine. Specially-prepared platelets taken from the patient which are then re-injected ... (2 to 3 mL) of this material over 500% richer in platelets than whole blood was then injected into the tendon of the sore elbow. These 15 patients had tennis...

Protein important in blood clotting may also play a role in fertility

... control blood clotting in humans by keeping blood platelets from sticking together, acting as a natural anti-c...oagulant to prevent uncontrolled clotting of blood platelets that might lead to heart attacks and strokes. From initial observations, the CIB1 defect in mice ap...

JCI table of contents: September 21, 2006

...ed by interactions between monocytes and activated platelets but it is indirect: activated platelets induce monocytes to produce a soluble factor known as IL-1-beta, which then acts on the monocytes to...

ACS News Service Weekly PressPac -- Sept. 13, 2006

...gakaryocytes (bone marrow cells that produce blood platelets that are responsible for blood clotting) derived from adult hematopoietic stem cells were, for the first time, reprogrammed into neutrophil-like cells similar to the white blood cells that are responsible for fighting infections, according to study l...

Stem cells: Chemistry paves way toward promising therapies

...gakaryocytes (bone marrow cells that produce blood platelets that are responsible for blood clotting) derived from adult hematopoietic stem cells were, for the first time, reprogrammed into neutrophil-like cells similar to the white blood cells that are responsible for fighting infections, according to study l...

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