Discovery about Vitamin C explains its metabolic value
...g." The new findings, the OSU scientists say, also points to new biomarkers that can be useful in identifying oxidative stress in the human body. They may provide an indicator of people who may be at special risk of chronic disease....Researchers discover new gene in colon cancer
...tz. "This interaction between TGF-beta and 15-PGDH points to the importance of the TGF-beta system in suppressing colon cancer. These genes give us targets that we can aim for in the development of new drugs or gene therapies that may help us treat or prevent colon cancer," said Markowitz, who is also an i...Baby songbirds and human infants learn sounds in similar ways
...zebra finches, a very flexible one. "This research points to a remarkable parallel in vocal learning in infants and some songbirds" says senior author Fernando Nottebohm, Ph.D., Dorothea L. Leonhardt Professor and head of the Laboratory of Animal Behavior at Rockefeller. "In both cases vocal learning seems ...Mutant gene linked to treatment-resistant depression
...ienced mild depression and anxiety symptoms. This points up the complexity of these disorders, say the researchers. For example, major depression is thought to be 40-70 percent heritable, but likely involves an interaction of several genes with environmental events. Previous studies have linked depression......n basic research and application. One of the focal points of his work is particle properties in the sub-micron size range. The behaviour of and interaction between particles are decisive for the characteristics of a product. Whereas in the past the particles of interest were larger than a micron, an increas...Weizmann Insitute scientists show how proteins beat the evolutionary stakes
...vities can provide nature with ready-made starting points for the evolution of new functions. Proteins that have evolved to perform a given function often have the ability to take on other, often completely unrelated tasks as well. For example, one of the enzymes studied by the group, PON1, is known to remo...Needling chromosomes yields insights into cell division
...eriments pulling the chromatids apart at different points along their length and at different times during cell division. The experiments revealed that the chromatids are attached to one another, but that they initially separate at their centers, zipping apart until they are entirely separate. Then, they ca...Healthy mix of GI tract microbes are key to preventing allergies and asthma
...d gut may not seem obvious at first. But Huffnagle points out that every time we swallow, particles of dust, pollen and spores trapped by mucus-producing cells and tiny hairs lining the respiratory tract are washed into the stomach where they come in direct contact with immune cells in the GI tract. "Thin...Evidence that human brain evolution was a special event
...e the powerful brain that exists in humans. Varki points out that several major events in recent human evolution may reflect the action of strong selective forces, including the appearance of the genus Homo about 2 million years ago, a major expansion of the brain beginning about a half million years ago...JCI table of contents, 3 January 2005
...h influences the accumulation of MTXPGs. The study points to new strategies to overcome these potential causes of treatment failure in childhood ALL. TITLE: Folate pathway gene expression differs in subtypes of acute lymphoblastic leukemia and influences methotrexate pharmacodynam...The death of a very special chimpanzee
... of sequencing. She points out that sequencing the human genome cost several hundred million dollars. Sequencing Clint cost only about $18 million. If prices continue to fall this steeply, sequencing other individuals will be so cheap that preserving biological material from t...Don't count on vitamin C to boost your exercise performance
... adults with acute administration." Real exercise points out complexity of interactions The report noted that: "Oxidized low-density lipoprotein concentration was negatively associated with maximum heart rate and was greater in the older compared with young adults and was reduced in both groups following a...Systems microbiology has great scientific promise in health and environment
... the University of Wisconsin, Madison. The report points out the single most critical need for systems microbiology is a centralized database to enable rapid submission and retrieval of data and to expedite access to information from diverse areas of research. Continued systems microbiology research will...Gene sequencing explains bioremediation 'bug'
...es is living the "runaway American dream." Zinder points to a map of the United States displaying contaminated sites at which naturally occurring Dehalococcoides has been found. However, Dehalococcoide is not found at all sites with chlorinated pollutants -- and at those sites bioremediation fails to ...High sugar levels increase cancer and mortality risk
...ucose intolerance, an emerging cause of cancer. It points to increased cancer risk as another adverse consequence of rising obesity around the world," concluded, Sun Ha Jee, PhD, MHS, lead author of the study and an adjunct assistant professor in the Bloomberg School of Public Health's Department of Epidemi...Scientists find missing link between whale and its closest relative, the hippo
...with the 20-year-old claim that molecular evidence points to the whale as the closest relative of the hippo. "The problem with hippos is, if you look at the general shape of the animal it could be related to horses, as the ancient Greeks thought, or pigs, as modern scientists thought, while molecular phylog...By age 6, children of overweight mothers are also prone to obesity
...kes Research Institute at Children's Hospital. "It points to an important target group--children whose mothers are overweight. There could be greater benefits to focusing intense prevention efforts toward these children, rather than to the entire pediatric population." The fact that increased body weight at...Potentially harmful fluoride levels found in some instant teas
...mulate fluoride from the soil and water. Our study points to the need for further investigation of the fluoride content of teas," says Michael Whyte, M.D., professor of medicine, pediatrics and genetics. "We don't know how much variation there is from brand to brand and year to year." In many communities in...Enzyme, lost in most mammals, is shown to protect against UV-induced skin cancer
...tance to UV-induced skin cancer. This work clearly points to CPD lesions as the major intermediate in UV-induced cellular damage leading to non-melanoma skin cancer. Importantly, it also suggests that photolyases may be successfully employed as a genetic tool to combat UV-induced skin cancer. Judith Jans, W......test. "We'll be able to compute mathematically the points in the system that are most crucial to test becaus...sign. Researchers could use models to find optimal points in a metabolic pathway for drug intervention that would achieve desired treatment results with minim...