Tag: "pombe" at biology news
Study suggests that publicly available genome data may contain small but significant errors
...d snippets from the genome of the fission yeast S. pombe
and examined how they bind to probes arrayed on a...g the genome. The resulting physical map of the S. pombe
genome was compared to the corresponding map computed from publicly available S. pombe
Heterochromatin assembly in S. pombe
...raig Peterson and colleagues have identified an S. pombe
ubiquitin ligase that is required for heterochromatin formation and gene silencing. The authors purified the heterochromatin assembly protein, Rik1, along with two novel Rik-1 associated proteins that proved essential for H3-K9 methylation and centro...
Yeast finding links processes in heart disease and cancer
...l-studied S. cerevisiae, or brewer's yeast, but S. pombe
seemed to have the right stuff. Graduate student Adam Hughes then examined the role of these similar genes to prove that they in fact duplicate the human process. Indeed, the yeast gene they called sre1 triggered activation of cholesterol-producing g...
For yeast, a DNA break ensures sex switch for a grandchild
...mating-type locus of the yeast Schizosaccharomyces pombe
is marked by a simple break on one strand of the DNA. One of the daughter cells will receive this nicked DNA upon cell division, and the nick serves as a signal for sex switching in the next generation. The researchers showed that the nick is site sp...