Tag: "pore" at biology news
New aerogels could clean contaminated water, purify hydrogen for fuel cells
...of the gels will allow researchers to "tune" their pore
sizes or composition in order to separate particular poisons from the hydrogen stream. "You can put in elements that bind the poisons that are in the stream or ones that bind the hydrogen so you let everything else fall through," Chupas said. For e...
Doing nature one better: Expanding the genetic code in living mammalian cells
...eeds through a small portal and blocks the central pore
of the channel. Wang and Slesinger used the new unnatural technology as a molecular ruler to answer the question whether increasing the size of the thread had an effect on the speed of inactivation" We introduced mutations into the thread, so it wo...
DNA sieve -- Nanoscale pores can be tiny analysis labs
...s for the first time that a single nanometer-scale pore
in a thin membrane can be used to accurately detec...similar to those in living cells, and "drilling" a pore
in it with a protein (alpha-hemolysin) produced by the Staphyloccoccus aureus bacteria specifically ...
Deactivating protein may protect nerve fibers in MS
...sponsible for causing the unregulated opening of a pore
in the mitochondrion's membrane that allows the ca...wn the cyclophilin D protein and the mitochondrion pore
it activates. "If you basically inhibited that protein with a drug, you would see the same axonal pr...
New diagnostic technologies offer non-invasive means
...rge that can pull the biomarker into an engineered pore
or it could consist of sticky molecule, like an antibody, that is designed to adhere to the biomarkers unique shape. Once it has captured a biomarker and been removed from the patient through a simple blood withdrawal, the hydrogel can be electrica...
Protein overexpression at heart of heart failure
...ac [Ca2+]i transients is calcium entry through the pore
subunit of the voltage-dependent L-type channels (...nsgenic mouse which was crossbred with the channel pore
overexpressing mouse when still nonfailing (Adaptive phase). In the nonfailing double transgenics, t...
Super-thin membrane, 50 atoms thick, sorts individual molecules
...accurate enough for engineers to simply select any pore
size and fabricate it. The researchers have just founded a company, SiMPore, to commercialize the numerous applications of the nanomembrane. Many of the University's laboratories will be involved in testing and developing the membrane, and the foun...
New mechanism for nutrient uptake discovered
... at the surface of the cell's outer membrane. Each pore
is capable of transporting nutrients individually, so we were really surprised to find that the pores simply can't act without stimulation from their neighbors." In earlier research the Carnegie scientists, with colleagues, identified the genes res...
MIT 'microsieve' could aid study of diseases
...he microchip is that it can have so many different pore
sizes, and unlike gels, it is possible to design an exact pore
size to increase the separation accuracy. That in turn can help researchers look for so-called bioma...
New approach could lower antibiotic requirements by 50 times
...nisms that enable them to throw out antibiotics. A pore
in the cell wall would obviously cancel the efflux effect,' Hagens explains. Pseudomonas bacteria cause pneumonia and are a common cause of hospital-acquired infections. Experiments in mice revealed that 75% of those infected with a lethal dose of ...
'Speechless' and 'Mute' help break the silence of the leaves
...opic pores that they can open and close as if each pore
was a tiny mouth. Plants wouldn't have been able t...e is being lost, the two cells around the stomatal pore
close it completely. Without the genes guiding stomatal development, plants won't develop any mouth...
Night of the living enzyme
... into active shape inside the pore. So loaded, the pore
is now open for business; substances in the soluti...nt, suggesting that the enzymes orientation in the pore
is important. It could be that in some cases the active site, the part of the enzyme that needs to...
Mind the gap
...ures and study the properties of water at confined pore
interfaces. "These studies will increase our knowledge of how water behaves in different environments. The structure of water in these environments is still, somewhat a mystery to us, despite the fact that our world is surrounded by water", declared ...
News tips from the Journal of Neuroscience
...ne domains must form a water-filled, funnel-shaped pore
within the enzyme complex where peptide bonds are cleaved....
NHGRI aims to make DNA sequencing faster, more cost effective
...age of single-strand DNA through a nanometer-scale pore
is driven by an electric field revealing informati...e sequencing approaches involve either the protein pore
alpha-hemolysin or artificial pores in inorganic materials. This team will use protein-engineering t...
One protein, two channels: Scientists explain mechanism in aquaporins
... simulations, the researchers explored the central pore
as a candidate pathway for conducting ions. Gating of the central pore
is controlled by cyclic guanosine monophosphate, a signaling nucleotide inside the cell, which induc...
MIT's molecular sieve advances protein research
...entists. "No one has been able to measure the gel pore
sizes accurately," said Jongyoon Han, the Karl Van... at MIT. "With our nanopore system, we control the pore
size precisely, so we can control the sieving process of the protein molecules." That, in turn, mea...
Discovery could aid fight against cystic fibrosis infection
...crystallographer Marianne Cuff saw a bagel-shaped pore
that might be involved in transferring toxins into cells. She deposited the structure of the protein, called Hcp1, into the Protein Data Bank, a resource used by biologists worldwide to find information about the proteins they are studying. While e...
NJIT professor to address Water Industry Conference At Harvard Club about desalinating water
...membrane cause the actual separation to occur. As pore
size decreases, the membrane's efficiency and selectivity increases. Membrane separation processes are used in biomedical, biotechnology, chemical, food, petrochemical, pharmaceutical and water treatment industries to separate/purify/concentrate liqu...
Why we could all do with a siesta
...ard-seeking and addiction. "We have identified the pore
in the membrane of orexin-producing cells that is responsible for the inhibiting effect of glucose. "This previously unknown mechanism is so sensitive it can detect minute changes in glucose levels -- the type that occurs between meals for example. "...
1 2 3