Tag: "potassium" at biology news

DNA meets heart drugs with resistance

...rt, beat quickly and inconsistently. Expression of potassium channel KCNA5 is confined to cells in the atria an...isms in KCNA5 have been identified, which make the potassium channel less sensitive to blockade by antiarrhythmic drugs, but appear otherwise indistinguishable f...

Corn fungus is nature's master blaster

...gus, at question was whether the sugar mannitol or potassium ions were responsible for the osmotic pressure that generated the propulsive force. In their experiments, Trail and Gaffoor created a fungal "shooting gallery" consisting of a small glass chamber, in which they mounted a block of gel-like agar contai...

Researchers make headway in mystery of migraines

...e." By expelling sodium from the cell, and drawing potassium from outside, the sodium pump maintains a gradient of potassium, which is critical for the propagation of electrical signals along nerve cells. Like an air conditioner in the heat of summer, the sodium pump is a massive energy hog, consuming around 3...

Jonathan Baell wins Biota Award for Medicinal Chemistry

...tency of this substance, which acts to disrupt the potassium channels of the body's rogue T cells, thereby reducing their capacity to cause damage to the body. Dr Baell, who heads the discovery team in the Medicinal Chemistry Group in WEHI's Structural Biology Division, says that the next step is to determine...

The relationship between lawns and allergies and asthma

...e a great source of nutrients, including nitrogen, potassium and phosphorus, reducing the need for additional chemical fertilization," Williams said. "They contribute organic matter to the soil over time. Bagging these materials for curbside garbage collection is costly, and it takes up limited landfill space....

It's electric: Cows show promise as powerplants

...s. The other chamber, the cathode, was filled with potassium ferricyanide, a chemical that acts as an oxidizing agent to round out the electrical circuit. Two small pieces of plain graphite served as the fuel cell's electrodes (an electrode draws and emits electrical charge.) A piece of graphite was placed in ...

Illinois research zeroing in on optimum soil nitrogen rates

...ecause of reduced mineralization." Low levels of potassium and/or phosphorous were noted for other high-testi...utilization of nitrogen," Khan said. "For example, potassium is involved in numerous enzymatic reactions in the plant, so even though nitrogen may be taken up wh...

Jefferson scientists uncover new clues to how crucial molecular gatekeepers work

... pores through which molecules such as calcium and potassium flow in and out of cells operate. Such channels can be extremely important; members of the voltage-gated ion channel family are crucial to generating electrical pulses in the brain and heart, carrying signals in nerves and muscles. When channel func...

Stem cells' electric abilities might help their safe clinical use

...ifferent cell types, from cancer to T-lymphocytes, potassium channels are responsible for altering the membrane... a cell cycle." Li hopes the targeting of specific potassium channels will give scientists more understanding and control in engineering healthy cells for transp...

New discoveries about neuron plasticity linked to learning and memory

...out the dendrite membrane and allow the passage of potassium and sodium ions into and out of the neuron, are altered during learning. "The h-channels undergo plasticity, not near the synapse but probably throughout the dendritic tree," says Johnston. To record the changes during learning, cells from the rat h...

Looking for the genes that affect a person's level of response to alcohol

...has an effect on what this gene controls, which is potassium flow. Our current results appear to show that the...intensity of the effects of alcohol on the flow of potassium in and out of cells." "We know that alcoholism/alcohol dependence is a complex trait, and that the ...

A salty tale: New bacterial genome sequenced from ancient salterns

...ve, S. ruber must maintain a high concentration of potassium inside its cytoplasm, keeping an osmotic balance against the high sodium chloride concentration outside. That's where evolutionary strategy comes in. Analyzing the bacterium's genome, researchers found that S. ruber's proteins are typically rich in ...

Science's Breakthrough of the Year: Watching evolution in action

...iled molecular portrait to date of a voltage-gated potassium channel was unveiled in 2005. These channels, gatekeeper proteins that usher potassium ions in and out of cells, are as key to nerve and muscle functioning as transistors are to computers...

Storing carbon to combat global warming may cause other environmental problems, study suggests

... trees must also remove nutrients like calcium and potassium and nitrogen from the soil, Jackson explained. During these chemical exchanges, "you leave sodium behind, which builds up in the soil to make it saltier," he said. Jackson's former postdoctoral scientist Esteban Jobbgy, now at the Universidad Nacion...

News tips from the Journal of Neuroscience

...ERG (ether-a-go-go-related gene)-likevoltage-gated potassium channel. Usingmutations in unc-103 that caused males toprotract spicule muscles in the absence ofmating cues, the authors discovered afunctional link between pharyngeal neuronsand muscles involved in feeding andthe mating-specific spicule muscles. ...

JCI table of contents, February 9, 2006

...Medicine in Connecticut report that CFTR regulates potassium levels via a functional interaction with a special potassium channel (or pore) known as ROMK (renal outer medullar potassium) specifically in kidney cells. The s...

Study implicates potassium channel mutations in neurodegeneration and mental retardation

...have linked mutations in a gene that regulates how potassium enters cells to a neurodegenerative disease and to... The gene codes for one of the proteins that form potassium channels pore-like openings in the cell membrane that control the flow of potassium ions into the c...

How sweet it isn't -- preference for alternatives to sugar based on sour, bitter tastes

...f the substances thaumatin, cyclamate, acesulfame potassium and glucose were ranked in between the most-preferred and the least-liked compounds. Delwiche plans to continue this work and include larger groups of participants to figure out what drives individual differences in taste perception. "There is a nee...

First direct mechanical communication of mitochondria, cardiomyocyte nucleus shown

...king the cytosol, 10 micro-molar of valinomycin (a potassium ionophore that induces mitochondrial matrix swelli...-molar of diazoxide (a mitochondrial ATP-sensitive potassium channel opener) reduced nuclear volume a similar amount. "However, 150 micro-molar of 5-hydrooxydeca...

New groundbreaking findings in taste, smell and chemical irritation

... involves, at least in part, fatty acid effects on potassium channels in taste cells. The sensitivity to fats a... of fatty acid-sensitive to fatty acid-insensitive potassium channels. The different channels that play these roles have been identified. Obesity's vicious cy...

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(Date:8/21/2014)... the journal Carcinogenesis by researchers at the ... protein adenomatous polyposis coli (APC) in suppressing colorectal cancer ... U.S. , Lead author Kristi Neufeld, associate professor in ... Cancer Biology program at the KU Cancer Center, has ... understand the various activities of APC, a protein whose ...
(Date:8/21/2014)... A team of researchers at Louisiana Tech ... using affordable, consumer-grade 3D printers and materials ... contain antibacterial and chemotherapeutic compounds for targeted ... doctoral students and research faculty from Louisiana ... collaborated to create filament extruders that can ...
(Date:8/21/2014)... State University have developed a novel and versatile modeling ... for creating new materials as well as for studying ... allows us to model much larger and more complex ... says Nan Li, lead author of a paper on ... Department of Materials Science and Engineering. "This is a ...
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