News tips from the Journal of Neuroscience
...ncoded channels was required for calcium-activated potassium current (I K(Ca) ). In cac mutant neurons, the inactivating potassium current I A was upregulated, an effect mimicked by chronic pharmacological block of cac channels,...News tips from the Journal of Neuroscience
...glia cells siphon activity-generated extracellular potassium ions to glial endfeet abutting small blood vessels...in arteriole diameter. In mice lacking Kir4.1, the potassium channel that is expressed at glial endfeet adjacent to arterioles, light-evoked vasodilation was sim...News tips from the Journal of Neuroscience
...A at the membrane, they used the calcium-activated potassium channels that underlie the slow afterhyperpolarization as a physiological reporter. Increases in PKA with 5-HT 7 receptor activation or direct stimulation of adenylyl cyclase with forskolin reduced the slow afterhyperpolarization potential current w...500,000 years of climate history stored year by year
...rofessor Litt explains. Using hydrofluoric acid or potassium hydroxide he dissolves the pollen grains from the sediment samples; the grains prove to be completely impervious to such rough treatment. Under the microscope the botanists then assess how much pollen of which species is present in the layer in quest...JCI table of contents -- March 22, 2007
...that causes high blood pressure and high levels of potassium in the blood. Recent studies have identified mutat...in known as ROMK1 (which is involved in regulating potassium uptake) by kidney cells, the molecular details behind this increased internalization have not been c...Too much of a good thing? Excess nutrients or water limit biodiversity
...ors (such as soil moisture, nitrogen, phosphorous, potassium and water)." It also helps explain why grasslands, lakes and rivers that are polluted with nitrogen and phosphorous (usually from agriculture) have fewer species. The reduction of species where the Mississippi River empties into the Gulf of Mexico...Bacterial response to oxidation studied as toxin barometer
...trons. Gram negative heterotrophic bacteria spit potassium in the presence of oxidative stress, said Nancy Lo...e non-scientist, the bacterias response of pushing potassium out of their cells in the presence of oxidative stress is called the glutathione-gated potassium eff...Too much water, fertilizer bad for plant diversity
...ng factors such as levels of nitrogen, phosphorus, potassium and water. ...News tips from the Journal of Neuroscience
... and express a metabolic sensor, the ATP-sensitive potassium channel K ATP . In rodent brain slices, ketone bodies (β- hydroxybutyrate or acetoacetate) slowed the firing of these cells by ~10%. Pharmacological activation of normally silent K ATP channels also slowed or silenced neuronal firing. The keton......otein units linked together. After the addition of potassium phosphate, a natural initiator of silk aggregation, the liquid could be pulled into threads. "It is clearly not a structural change in the protein, but rather the degree of oligomerization that is crucial for thread formation," concludes Scheibel. T...Pimp my meatballs -- collagen injections safeguard nutrients
...lagen fibre or collagen hydrolysate saturated with potassium iodide to meat makes it more stable than potassium iodide introduced using iodized table salt. The collagen enhancement works on fresh meat before cook...News tips from the Journal of Neuroscience
...s, regulates cell firing in many cell types. These potassium channels, composed of KCNQ2/3 heteromers, are low threshold and noninactivating, thus reducing action potential firing to sustained stimuli. As per the name, muscarine blocks M-current. This week, Crozier et al. examine the interaction of M-current i...Richard Lifton awarded at WCN 2007
...ularly for studies of the mechanisms of sodium and potassium handling by the kidney and the role of mitochondrial genetic mutations. His role in connecting traditional renal physiology with the modern sciences of genetics and molecular biology has also been paramount. Setting the scientific stage for 4 da...New study suggests beverage patterns may 'make or break' your diet
...r in vital nutrients including calcium, magnesium, potassium and vitamin A. In the general population, sweetened beverages substantially contributed to calories and added sugar intakes, while providing fewer nutrients other than vitamin C. "Our research tells us that beverages make significant contributions......eart rate. "The enzyme works through calcium and potassium channels that we know to be key players in the generation and regulation of the pacemaker activity," said Ke. "Although adrenaline and other mechanisms that accelerate the heart rate have been well studied, mechanisms that might act as a brake are ...When the villain becomes your friend: The strange tale of muscle lactate
...muscles, the study examined the combined effect of potassium ions, lactic acid and adrenaline on the electrical...ve to help working muscles ward off the effects of potassium ions which leak from the inside to the outside of working muscle cells and negatively effect the sig......poor conditions. On soils where little nutritional potassium is available, a commonproblem after many years of ...;1 transporter to replace some of the functions of potassium and actually enhancegrowth. This improvement of our understanding of how plants regulate salt uptake......types dominated by turfgrass showed differences in potassium and phosphorus levels and in bulk density, most likely due to fertilization and trampling that is typically associated with turf areas. Researchers also discovered differences in soil pH between residences and other land uses dominated by turgrass, ...Bright future for nano-sized light source
...archers describe a technique in which nanowires of potassium niobate were synthesized in a special hot water so...anowires to be grabbed and manipulated. Because of potassium niobates unique optical properties, this same beam of infrared laser light also served as an optical...Doing nature one better: Expanding the genetic code in living mammalian cells
... the molecular gates that regulate the movement of potassium ions in and out of nerve cells. In the past, thi...tional mutagenesis to introduce mutations into the potassium channel but it didnt give us any answers, says Paul A. Slesinger, Ph.D., an associate professor in t...