Little lifesavers -- Nanoparticles improve delivery of medicines and diagnostics
...hich would theoretically allow enough time for the potent packages to slip into the solid tumor cells they encountered throughout the body. In the lab, this is precisely the amount of time it takes for water molecules to work their way into the centers of the nanoparticles and degrade them. The team made...Better together: Bacterial endosymbionts are essential for the reproduction of a fungus
...the endofungal bacteria in return provide a highly potent toxin for defending the habitat and accessing nutrients from decaying plants. ...Natural mechanism for immune suppression paves way for cancer trials
...st immunity," says Dr. Mellor. "HIV certainly is a potent inducer of this mechanism." He suspects other diligent viruses and bacteria are as well. "This is obviously an evolutionary adaptation that the pathogen has to protect it from being eliminated by the host," he says. "That is why the infection does ......loy this strategy as well before launching certain potent weapons of the immune system. Interferons, which were discovered 50 years ago, are the body's first line of defense against viral attack. They are produced in cells that have been invaded by viruses, and from there they spread out to warn other cel...Smithsonian-led Amazon research team wins scientific prize
...onal Academy of Sciences, describes the remarkably potent impacts of habitat fragmentation on the Amazon ecosystem. The Amazon contains the planets most biologically diverse tree communities, with up to 300 species existing in an area the size of just two football fields. These forests are being felled ra...Ladybugs may be cute, but watch out when they get near wine
...ss of compounds called methoxypyrazines, which are potent odor-producing compounds also found in other animals and plants. The compounds are not considered harmful to humans. However, according to Koziel, even tiny amounts can be detected by the human nose. Ladybugs are loaded with these foul-smelling compo...Targeting tumors the natural way
...o the alpha-Gal on the organ's cells, unleashing a potent immune response that caused immediate organ rejection. But true to natural cell recognition, the immune response occurs only when clusters of many alpha-Gal molecules are present for anti-Gal to bind with. Armed with this knowledge, Kiessling's grou...Researchers uncover protection mechanism of radiation-resistant bacterium
...ging the focus from DNA damage and repair toward a potent form of protein protection. These findings point to new avenues of exploration for radioprotection, which could eventually influence how individuals are treated for exposure to chronic or acute doses of radiation; could lead to ways to protect cancer...Scientists unlock mystery of embryonic stem cell signaling pathway
... the cells to keep dividing and to remain as fully potent stem cells. This way, you can essentially maintain the stem cells growth and potency for as long as you want, Kahn says.The studies of IQ-1 and its effects reported in the newly published PNAS paper were performed at the University of Washington in S...One small step for Deinococcus or one giant leap for radiation biology?
...o decades, and points directly at the existence of potent manganese-based radioprotectors that prevent protein damage. Daly expects that delivery of purified radioprotective Mn-complexes into sensitive cell-types will make them temporarily radiation resistant. This possibility opens up new avenues for radio...Trojan horse strategy defeats drug-resistant bacteria
...medicine and microbiology at the UW. "The body has potent defense mechanisms to keep iron away from infecting organisms, and invaders must steal some if they are to survive." Iron is critical for the growth of bacteria and for their ability to form biofilms, slime-encased colonies of microbes that cause ...New bird species found in Idaho
...s Benkman. It also shows that coevolution can be a potent force for rapidly generating biodiversity....JCI table of contents: March 15, 2007
...t patients. TITLE: Artificial lymph nodes induce potent secondary immune responses in naive and immunodeficient mice AUTHOR CONTACT: Takeshi Watanabe Research Center for Allergy and Immunology, RIKEN Institute, Yokohama, Japan. Phone: +81-45-503-7025; Fax: +81-45-503-7004; E-mail: wtakeshi@rcai.riken.j...Prefrontal cortex loses neurons during adolescence
...Juraska said. "We know that experiences are very potent in younger children because their brains are developing," Juraska said. "So if there is another time that the brain is changing, then everything that happens can be written in and magnified more than during stable times." The finding that females l...Lung cancer-derived EGFR mutants exhibit intrinsic differences in inhibitor sensitivity
...ection for the design and development of even more potent inhibitors that are tailored to specific EGFR mutants. Many human malignancies exhibit mutated forms of the EGFR, a tyrosine kinase that plays a critical role in signaling pathways controlling cell proliferation and survival. Although the specific ...Researchers learn what sparks plant growth
...ant tissues. According to Chory, brassinolide is a potent growth hormone involved in the plants response to light. Such responses, which include adjusting plant growth to reach light or strengthening stems to support leaves, are central to plant survival. Brassinosteroid biosynthesis has become a critically...UBC researcher finds new way to treat devastating fungal infections
...lipid-based formulation) so that Amphotericin B, a potent anti-fungal agent, can be taken by mouth with minimal side effects. The agent, used for about 50 years, is currently administered intravenously and has significant toxic side effects, notably severe kidney toxicity as well as serious tissue damage at...ACS News Service Weekly PressPac -- Feb. 21, 2007
... in a different way than existing agents and is so potent that minute levels of 10 parts per trillion block ...olleagues describe the compound as one of the most potent of all anticancer agents in a report scheduled for the March 7 issue of the Journal of the American ...Magic beans -- Anti-obesity soya could help prevent diabetes
...archers has shown that black soya may be even more potent in rats, and also prevents weight gain (Journal of the Science of Food and Agriculture, February 2007 DOI: 10.1002/jsfa2808). The researchers, led by Shin Joung Rho at Hanyang University, Seoul, allowed 32 rats to gorge on a fatty diet, supplement......dersea landslides may play a role in releasing the potent greenhouse gas methane into the ocean and atmosphere. Yet new evidence suggests that a huge, ancient, submarine landslide belched little if any methane. Paull et al. studied the 8,000-year-old Storegga Slide, the largest known of many landslide scars...