Oh, rats! Designer animals reveal possible heart disease genes
...ization. Scientists have struggled to pinpoint the precise genes behind this complex disease. Now, however, they have a new research ally: the designer rat. In a four-year study published in the January 15 advance online publication of Nature Genetics , researchers at The Institute for Genomic Research (T...The closest look ever at the cell's machines
...tional, snap-on molecules that give each machine a precise function. That provides an economic way to diversify biological processes and also to control them." Thus if the cell needs to respond quickly, such as in a disease or another emergency, it may only need to produce few parts to switch on or tune the...Common molecular 'signature' identified in solid tumors
...t I am convinced that this field will give us more precise and less toxic ways of dealing with cancer than we have today even considering some of our new, molecularly-targeted therapies." Support from the research came from the National Cancer Institute, the Italian Ministry of Public Health, the Italian Mi...Birth defects: 8 million annually worldwide
...physical malformations. The data do not allow for precise comparisons of birth defects prevalence among countries, according to its authors, Arnold Christianson, M.D., of the National Health Laboratory Service and University of the Witwatersrand, Johannesburg, South Africa; Bernadette Modell, M.D., Ph.D. of...Airborne and satellite radars record Frascati grape harvest
...e area of interest to act as reference points. The precise aircraft route was tracked using GPS backed up by an onboard inertial navigation system (INS). "The SAR image acquisitions were accompanied by contemporary ground measurements on the vineyards," explained Prof. Domenico Solimini of the University of...Researchers alleviate symptoms of Rett syndrome in mice
...ur?" "Knowing more about the process and about the precise areas of the brain that are affected will give us options for exploring future therapies," explains Jaenisch, who is also a professor of biology at MIT. "We're encouraged by these results," says Monica Coenraads, co-founder and director of research ...Engineered heart tissue offers insights into irregular heartbeats, defibrillator failure
...ells into culture dishes on which they had stamped precise patterns of proteins known to support heart tissue growth. The proteins caused the cells to orient themselves, interconnect and grow in a manner that mimics normal heart tissue, Bursac explained. The team then induced electrical activity in these eng...UF scientists trace origin of shark's electric sense
...tic field for navigation, enabling them to swim in precise paths across large expanses of featureless ocean, Cohn said. "If you think of this in the big picture of evolution of sensory systems, such as olfaction, hearing, vision and touch, this shows sharks took a pre-existing genetic program and used it to ...Berkeley researchers lay groundwork for cell version of DNA chip
...ted cells ill-suited for applications that require precise patterns of multiple cell types. The authors behind the Angewandte Chemie paper have solved the problem with the creation of a highly selective cell adhesion system that uses single-strands of synthetic DNA to fasten the cells to a surface. This ena...Two NIH initiatives launch intensive efforts to find roots of common diseases
...ne by allowing us to predict disease, develop more precise therapies and, ultimately, pre-empt the developmen...tain health or lead to disease. Without these more precise measures of exposure, it will be very difficult to figure out why certain people develop disease and...Wisconsin scientists find a way to make human collagen in the lab
... atom at a time and we can manipulate them in very precise ways." The new Wisconsin study, which was supported by grants from the National Institutes of Health, lays a foundation for bringing human collagen to the clinic, says Raines. But he notes there is still some work to be done to perfect the technology...UCLA engineering and Mattel Children's Hospital collaborate to develop children's heart valve
...oin area, guided into place and then deployed in a precise location within the heart. As the valve is released from the catheter, it springs back to its original shape and begins to function. "What is really novel about the valve UCLA Engineering has created is the memory retaining alloy and butterfly design...Gene design program from Johns Hopkins simplifies, automates and speeds design of 'artificial' genes
...chardson. "That would make it impossible to do the precise cutting and pasting needed to make and use artificial genes," she said. However, even a successfully designed gene would not benefit researchers if there were only one copy of it. "To make use of artificial genes we need to make millions of copies of...Vanderbilt-Ingram Cancer Center studies effects of cancer treatment among children of survivors
...rge groups of cancer survivors in order to develop precise estimates of risk," Boice said. Already, over 59,000 cancer survivors who had 19,000 children have been identified in Denmark and Finland. Over the next five years, the study team will continue to identify survivors and their children, as well as si...Engineering nerve jumper cables for spinal cord repair in animal model
...wly pulled apart over a series of days, aided by a precise computer-controlled motor system. In this study, the neurons were elongated to 10mm over seven days after which they were embedded in a collagen matrix (with growth factors), rolled into a form resembling a jelly roll, and then implanted into a rat ......ray, so they can systematically obtain continuous, precise tracks of animal locations, including daily travels and frequently visited areas. "This study will generate a very valuable set of information," said Dr. Jerry Ault, professor of marine biology and fisheries at the Rosenstiel School. "If we know ho...Westmead leads Australian bird flu research
...Jon Iredell. "This means it can be adapted to make precise diagnosis in an individual or to test a planeload passengers in a couple of hours" "We can also use it in hospitals to detect illnesses which mimic or worsen flu and to pick up any flu cases that may be resistant to treatment". Researchers at the Cen...Researcher looks for more targeted way to deliver cancer drugs
...target. His method can also be used to create more precise images of diseased tissue. He is using a combination of amino acids called the TAT peptide as a carrier molecule. This positively charged molecule normally carries a protein toward the cell's membrane, which has a negative charge. Yang gives it a dru...Genetic and environmental influences on alcohol consumption among rhesus monkeys
...n human groups, but there is always the problem of precise measurement of phenotype and controlling for environmental variation in human studies which is not as great an issue in animal studies."......he cultured taste cells, researchers now have more precise control over the cell's surrounding environment, as well as better access to subcellular mechanisms, allowing them to ask certain questions that could not previously be addressed. For instance, cultured cells can be used to study how taste stimuli i...