X-ray images help explain limits to insect body size
...st size of currently living beetles. The head data predicted an unrealistically large, foot-long beetle. In contrast, the leg data predicted a beetle that nicely matches the size of the largest living beetle, Titaneus giganteus . This stud...OHSU turns mouse into factory for human liver cells
...ing metabolites. The conversion of drugs cannot be predicted with any current technology, such as computer models. You actually have to see what human liver cells do with any given drug." And human liver cells must be used instead of cells from laboratory animals because liver enzymes that break down these c...American Chemical Society's Weekly PressPac -- Aug. 1, 2007
...selected according to tumor cell type and patients predicted responses to different kinds of anti-cancer drugs. Their paper describes key features of state-of-the-art proteomic profiling, in which blood tests are used to analyze single proteins and multiple fingerprint protein patterns that are present, includ...Computer graphics spills from milk to medicine
..., said Jensen. Once their new theoretical model predicted the relevant physics for light hitting participating media, the researchers took the next step and made the results useful for computer graphics by determining how the light would actually scatter and be absorbed. It is this information that is used ...Anthrax bacterium's deadly secrets probed
...into the workflow. The number of secreted proteins predicted for each member ranged between 350 and 500. The...ic family members were of unknown function. The predicted secreted proteins from Bacillus anthracis help to explain its inability to grow in soil. When we loo...Gene predicts better outcome as cortex normalizes in teens with ADHD
...ular gene version increased risk for ADHD, it also predicted better clinical outcomes and higher IQ than two other common versions of the same gene in youth with ADHD. Since this gene version had similar structural effects in healthy children as in children with the disorder, our findings suggest that ADHD...New survey documents the headaches of computerized medicine
...ored and managed: once unintended consequences are predicted or detected, their management can knowingly involve tradeoffs. An example of a CPOE-related tradeoff is the degree to which the extra time physicians must exert to use CPOE (an undesirable consequence) is offset by the increased information physician...Forecasting system provides flood warnings to vulnerable residents of Bangladesh
... to reach additional residents in coming years. It predicted the current floods a few days in advance, alerting a network of volunteers in Bangladesh last week to notify residents at risk. The volunteers cannot yet confirm the extent to which these efforts helped people prepare for the floods. "Our goal is t...Unknotting DNA clue to cancer syndrome
...While these experiments were done in yeast, Hunter predicted that the results could be extended to human cells. "This is a fundamental insight into the mechanism of DNA-break repair," he said. ......roject although the DSB frequency was the same as predicted by the models, the RIF in real microscope images w...nts to gamma rays and found that whereas the model predicted that these breaks would occur in a random pattern in three dimensions throughout the nucleus (not al...Biologists at Tufts University discover 1 reason why chromosomes break, often leading to cancer
... structure leads to fragility Past research had predicted the flexibility of the DNA helix in this particula.... "What we did was take two of these regions of predicted high flexibility, plus a region near a cancer cell breakpoint and a control region, and test whether...JCI table of contents: August 1, 2007
...ther the dangers of retroviral gene therapy can be predicted and/or eliminated. TITLE: Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy AUTHOR CONTACT: Christof von Kalle National Center for Tumor Diseases, Heidelberg, Germany. Phone: 49-6221-56...American Chemical Society's Weekly PressPac -- July 25, 2007
...hat exposure. Past research, the report notes, had predicted that certain metabolites compounds formed in the bodies of people exposed to diesel exhaust should appear in the urine. One of those compounds is known by the acronym 1-NP and its metabolites are OHNAAPs and OHNPs. This is the first study to demo...News tips from the Journal of Neuroscience
...ed their models until they found one that reliably predicted the ISI distribution. The models assumed that excitatory release events occurred at random times and that each event caused a spike unless the fiber was refractory. Their results suggest that spontaneous release from the ribbon can be described as a ...Uncovering the secrets of the deep
...edicts nearly 6 million proteins. By combining the predicted protein sequences with automatic classification by InterPro, the EBIs integrated resource for protein families, domains and functional sites, UniMES uniquely provides free access to the array of genomic information gathered from the sampling expediti...Learning a second language -- Is it all in your head?
...han two or three sessions -- the nine participants predicted on the basis of left HG size to be more successful learners achieved an average of 97 percent accuracy in identifying the pseudo words. The less successful participants averaged 63 percent accuracy and sometimes required as many as 18 training sessio...Call for EU to launch major project to map out all our proteins
...he genes and their protein products have only been predicted by computer algorithms that are at this time imper... complex, contain a significantly higher number of predicted protein coding genes than experimentally detected proteins. The shortfall is significant in almost...Scientists discover new way to study nanostructures
... for which he shared a 1973 Nobel Prize, Josephson predicted that when a constant voltage difference is maintai...nt first principles calculations by Landman's team predicted that such peaks would occur at three different frequencies, or voltages, and their integer multiples...Limpets reveal possible fate of cold-blooded Antarctic animals
... Antarcticas unique ecosystem. Sea temperature is predicted to increase by around 2C in the next 100 years. If cold-blooded Antarctic animals cant grow efficiently, or increase their growth rates, they are unlikely to be able to cope in warmer water, or compete with species that will inevitably move into the ...Measuring the unseeable: Penn researchers probe proteins' dark energy
... results, most researchers in our field would have predicted that entropys contribution to protein-protein interactions would be zero or negligible, says Wand. But now its clearly an important component of the total energy in protein binding. Because of this new information, the researchers suggest that the...