Scripps scientists identify target of an immune suppression molecule called CD22itself
... of B cells. CD22 acts as a safety valve of sorts, preventing the accidental or aberrant activation of B cells. Evidence for CD22's role, says Paulson, can be seen in mice that have no CD22 molecules. These mice have a hyperactive immune system and are prone to developing spontaneous autoimmune disease. What ...UNC plant researchers discover proteins interact to form hair-trigger protection against invaders
...nfected plants cells quickly commit suicide, often preventing the invader from destroying the entire plant. The new discovery appears to be a universal mechanism for defense by all plants against not only bacteria and viruses, but also parasitic fungi, insects and worms, he said. "This work is important because...The health effects of weight loss need more research
...desirable, emphasize the researchers. But overall, preventing people, especially children, from becoming overweight in the first place seems crucial, since this work suggests that once weight is gained losing it again may not be good for health....New study suggests role for clazosentan in the prevention of cerebral vasospasm after aneurysmal SAH
... on experimental studies, has a real potential for preventing vasospasm and, based on preliminary clinical studi...se the efficacy of 3 dose levels of clazosentan in preventing the occurrence of cerebral vasospasm following SAH, assessed by angiography. As a secondary endpoin...UF researchers test drug that could cut orthodontic treatment time in half
...ise that it will further soften gum tissue fibers, preventing them from pulling teeth back into their original position. The study will be the first of many to test the hormone as an orthodontic therapy, and it is hoped the drug could cut treatment time in half and eliminate the need for retainers after braces ...Women's health study finds vitamin E does not protect women from heart attack, stroke, or cancer
... no benefit of aspirin (100 mg every other day) in preventing first heart attacks or death from cardiovascular causes in women but did find a reduced risk of stroke overall, as well as reduced risk of both stroke and heart attack in women aged 65 and older. In recent years, there has been a great deal of pu...Nerve protector could make for new stroke treatments
...preserve the action of tPA as a clot buster, while preventing concurrent nerve damage," he suggests. "This would improve stroke therapy." The researchers are now working on chemical derivatives of SB-3CT, to determine the chemical formula that best blocks the activity of MMP-9 in the safest possible manner. O...Researchers discover how tumor suppressor gene works
... producing a protein that attaches to the enzymes, preventing them from performing their function. When the researchers added the p16 protein to colonies of cancer cells in culture, it diminished the size of many colonies, wiping out some of them. It also decreased the total number of cancer cells. The researc...Meaningless sex? Male mounting reduces sexual promiscuity of females
...some species, males may avoid sperm competition by preventing females from mating with other males. However, pre...ght plastic harness covering their cloaca and thus preventing insemination--the researchers were able to separate the effect of insemination products from that of...Newly discovered role for heart response enzyme may yield better heart failure therapy
...be activated, a process called phosphorylation. By preventing activation of tropomyosin by PI(3)K in cells, the researchers prevented heart receptors from leaving the cell surface, thereby blocking the initial step that occurs during heart failure. Also, the researchers reported, when they eliminated tropomyosi......ing drugs to remove tapeworm from a population and preventing the reinfection of the human population by vaccinating pigs," he says....U of MN researchers reverse memory loss in mice
...isease treatments focus on slowing the symptoms or preventing the disease from progressing, but our research suggests that in the future we may be able to reverse the effects of memory loss, even in patients who have lost brain or neural tissue," said Karen Ashe, professor of neurology and lead author of the st...Chemical 'band-aid' prevents heart failure in mice with muscular dystrophy
...poloxamer 188 could be a new therapeutic agent for preventing or limiting progressive damage to the hearts of patients with muscular dystrophy," Metzger says....UCI researchers define estrogen's role in limiting heart disease in women
...port indicating that estrogen is not beneficial in preventing coronary heart disease," said Levin, a professor of medicine, biochemistry and pharmacology, and director of endocrinology at UCI and the affiliated Veterans Affairs Medical Center in Long Beach, Calif. "Our work suggests that further in-depth studie...World-record magnet to pull in scientific breakthroughs
...tein (the M2 protein) in the influenza viral coat, preventing it from functioning and terminating the viral infection. Today, we are using the new magnet with collaborators from Northwestern University and Brigham Young University to define the detailed shape and chemical properties of the M2 protein so that a ...FSU food scientist is lead scholar in trade
...inese officials then were concerned primarily with preventing the introduction of Scrapie disease -- like BSE a member of the Transmissible Spongiform Encephalopathy (TSE) family but spread exclusively through infected ovine (sheep) by-products. They agreed to consider Hsieh's Rapid Reveal test for BSE adultera......mine in real time how much fertilizer to apply. By preventing waste, the system could decrease the cost of crop production and dramatically cut the nitrogen-laden runoff responsible for algal blooms and other damage to wetlands and waterways. Steve Finkelman, Paul Nordine and their colleagues at Containerless R...Blink, and the brain misses it
...reness during blinks may be a neural mechanism for preventing the brain from becoming aware of the eyelid sweeping down over the pupil during a blink and the world going dark," explains Professor Frith. In summing up the study's implications, the authors suggest that when we blink, the brain may just miss it....... expressed that would otherwise cause deafness. By preventing its expression, we prevented the deafness," said Smith who was senior author of the study. "Even though this is in the early stages, it is really exciting because it points to other options for people who have hearing loss other than hearing aids or ...... that such information might reveal strategies for preventing and treating malaria--the researchers used x-ray crystallography to determine the atomic structure of a key portion of the EBA-175 protein called the RII domain. The results revealed that two molecules of RII come together in a manner resembling a h...