Tag: "prevents" at biology news

Amgen investigational therapy, AMG 162, increased bone mineral density with twice yearly injection

...oclast precursors. By binding to RANK Ligand, OPG prevents the formation and activation of osteoclasts and helps keep the bone loss process in check. Amgen developed AMG 162 to mimic the effects of OPG, enhancing the body's own process to specifically inhibit the effects of RANK Ligand. Observations from...

Low dose radiation evades cancer cells' protective 'radar'

...f radiation fail to switch on the ATM radar, which prevents an error-prone repair process. DeWeese, who will present his evidence at the annual meeting of the American Society for Therapeutic Radiology and Oncology on October 5 in Atlanta, explains. "DNA repair is not foolproof - it can lead to mistakes or mu...

Botulism bug says no to nitric oxide, provides key to molecule's role in human cell signaling

...-old practice of treating meat with sodium nitrite prevents life-threatening food poisoning known as botulism. Discovering how botulism-causing Clostridium botulinum detects nitric oxide (NO) sheds light on how NO connects with its receptor protein in humans to govern crucial processes in the cardiovascula...

Protein protecting brain from toxins also blocks some chemotherapy from reaching tumors

...illaries are tightly joined to form a barrier that prevents most substances from leaving the blood. This cellular barrier, called the blood-brain barrier, prevents certain substances from leaving the bloodstream and entering the brain. Mrp4 in the blood-brain barr...

Technique for genetically modifying blood stem cells brings cure for blood diseases closer

...ing the fetal stage of development. The use of HbF prevents the need to introduce normal beta-globin into the body in someone who has never had it before. It is possible that the sudden introduction of beta-globin could trigger an immune response against this protein. The vector, which used a vi...

Experimental drug prevents vaginal simian HIV transmission in monkeys Science study says

...idate molecule to a topical agent that effectively prevents sexual transmission of HIV will require resolving many difficult issues. The required drug dosage, for example, must be better understood and reduced. Also, the authors did not test if the drug protects against transmission of SHIV contained within i...

Time-lapse movies show brain cells move like a two-stroke engine

...ew that disrupting the cytoskeleton with chemicals prevents the cell from moving. In addition, problems with the cytoskeleton are implicated in human disorders in which nerve cells fail to migrate properly, such as Miller-Deiker syndrome. But no one had previously watched the cytoskeleton in living neurons in...

Researchers find protein that makes long-term memory possible

... the mouse hippocampal slices with a compound that prevents new proteins from being made. Protein synthesis is essential for the formation of long-term memory and, before the current study, researchers had searched for years to identify exactly which proteins were needed in the process. As expected, applyin...

Normal cells in tumors may aid cancer growth

...meday develop a drug that targets stroma cells and prevents the cancer from spreading." Eng and her colleagues analyzed 134 tissue samples from invasive breast tumors. They examined stromal cells known as fibroblasts, the major component of the tumor stroma. Fibroblasts produce the fibrous scaffolding i...

Delay in cutting the cord helps premature babies

...both early and delayed clamping. Clamping too soon prevents blood from returning through the umbilical cord to the baby's body. "A little extra blood can help restore blood pressure," says Raju. Low blood pressure may require transfusions of blood or fluids, which can be tricky to accomplish safely in a prete...

Lag-3 gene dampens immune responses by controlling regulatory T-cell function

... "The braking action of regulatory T cells prevents the destructive effects of autoimmune diseases, such as diabetes type 1, which occurs when effector T cells mount an attack on the cells of the pancreas that produce insulin," Vignali said. However, regulatory T cells can also block the...

Calorie restriction leads to some brain benefits but not others in mice

...Louis, Oct. 24, 2004 -- Severe calorie restriction prevents certain aging-related changes in the brain, including the accumulation of free radicals and impairments in coordination and strength, according to a mouse study at Washington University School of Medicine in St. Louis. However, the dietary changes di...

NIH funds rare childhood disease to provide insights into the origins of adult cancer

...n infancy, DBA is an inherited blood disorder that prevents the bone marrow from producing sufficient red blood cells, which carry oxygen to all tissues in the body. Those red blood cells that are produced are often large in size and do not function properly. All other blood cells -- white blood cells and pla...

JCI table of contents November 1, 2004

...e inhibits the profibrogenic activity of TGF-b and prevents bleomycin-mediated lung fibrosis AUTHOR CONTACT: Edward B. Leof Mayo Clinic, Rochester, MN 55905, USA Phone: 507-284-5717; Fax: 507-284-4521; E-mail: leof.edward@mayo.edu View the PDF of this article at: https://www.the-jci.org/press/19603.pdf ...

Scientists raise concerns about second wave of 'mad cow' prion infection

...S., commenting that inadequate reimbursement often prevents or delays the adoption of new technology to enhance blood safety. He said that improvements in transfusion safety are not likely to be implemented in the U.S. without patient advocacy. Dr. Ness reviewed U.S. blood safety measures and noted that leu...

Scientists uncover secret to sharp teeth

.... Further investigation revealed that follistatin prevents enamel formation by inhibiting BMP signaling molecules that are potent stimulators of ameloblast differentiation. The researchers conclude that asymmetric expression of follistatin accounts for the distinct patterning of enamel formation in mouse inc...

By impounding iron, FHC foils cell suicide, fuels inflammation

...ke the harmful substances that induce death -- FHC prevents cellular suicide. This finding suggests that dru... early stages of an infection, for instance, NF-kB prevents white blood cells from dying off, allowing them to multiply quickly to fight off infection. The pr...

UCSD researchers find effective treatment for unusual fever syndrom caused by cold exposure

...akinra, which inhibits the action of IL-1 and thus prevents acute inflammation, fever and flu-like symptoms. The treatment prior to cold exposure prevented the clinical and laboratory manifestations of the disease in the FCAS patients. Anakinra is currently approved by the Food and Drug Administration for t...

Molecular technique shows promise in destroying drug resistance in bacteria

...ed apramycin that binds to plasmid-encoded RNA and prevents proper plasmid reproduction. Apramycin was chosen after numerous potential aminoglycosides -- a group of antibiotics effective against gram-negative bacteria -- were tested to find those that bind tightly to the target plasmids. Positively charged a...

UCLA scientists uncork fountain of youth for HIV-fighting cells

...ntists have shown that a protein called telomerase prevents the premature aging of the immune cells that fight...activity in immune cells from HIV-infected persons prevents telomeres from shortening. "This is the first step toward developing other telomerase-based strate...

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(Date:10/22/2014)... , Oct. 20, 2014  Leading identity analyst ... time half of the world,s population will have a ... Europe . Asia ... the market accounting for more than 60% of all ... Acuity,s report  -- "The Global National eID ...
(Date:10/19/2014)... access in India over the last 30 years ... emissions growth during that time, according to a ... Climate Change ., "Energy access is fundamental to ... life, including education, communication, and health," says IIASA ... While increased energy access is widely agreed to ...
(Date:10/18/2014)... referred for evaluation of suspected genetic conditions, whole-exome ... percent, including detection of a number of rare ... according to a study appearing in JAMA ... with the American Society of Human Genetics annual ... coding regions of thousands of genes simultaneously using ...
Breaking Biology News(10 mins):Half the World's Population Will Have Chip-Based National Electronic Identity (eID) Cards by 2018 2Improved electricity access has little impact on climate change 2Whole-exome sequencing shows potential as diagnostic tool 2
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