Tag: "principle" at biology news

Role of thyroid hormones in slumber under investigation at Rutgers

... Joseph V. Martin, a professor of biology, is the principle investigator and Alex Roche, an associate professor of chemistry, is the co-principal investigator of the ambitious project at Rutgers-Camden. A diagnosis of thyroid cancer in 1991 inspired Martins in-depth studies of thyroid hormones for over a de...

Hepatitis C helicase unwinds DNA in a spring-loaded, 3-step process

...t utility vehicle. Its not fuel efficient but in principle it could also go off-road, carry some luggage or maneuver around barriers, he said. So it may actually make sense to develop a low-efficiency motor because then you have extra energy to do extra work when needed. Myong noted that NS3 is the only he...

House backs taxpayer-funded research access

...Appropriations Bill. The House has affirmed the principle that broad sharing of publicly funded research findings on the Internet is an essential component of our nations investment in science, said Heather Joseph, Executive Director of SPARC (the Scholarly Publishing and Academic Resources Coalition), and ...

Synthetic adhesive mimics sticking powers of gecko and mussel

...ong but temporary adhesion comes from a mechanical principle known as contact splitting. Each gecko foot has a flat pad that is densely packed with very fine hairs that are split at the ends, resulting in a greater number of contact points than if the hairs were not split. (The diameter of one of the split hai...

Nature's secrets yield new adhesive material

...versible adhesive. Our work represents a proof of principle that it can be done, said Phillip Messersmith, D. D.S., Ph.D., a scientist at Northwestern University in Evanston, Ill. and the senior author on the paper. A great deal of research still must be done to refine the fabrication process and greatly red...

UF scientists work to develop simple bladder cancer test

...ber of patients so far, this was really a proof of principle that we can use these new techniques to detect proteins in the urine, Goodison said. Nobody could do that at this (degree of) sensitivity until now. The study was funded through a grant from the Florida Department of Health. Goodisons collaborators...

U-M researchers discover gene switched off in cancer can be turned on

...HDAC inhibitors are not the perfect answer, but in principle this tells us we can turn our gene back on. If we can turn the gene back on, it may not be a cure for cancer, but it could slow it down or make it responsive to existing drugs, Reisman says. The researchers targeted lung cancer cell lines in partic...

ESA's water mission instrument passes test program

...centre of gravity and the inertia around its three principle axes. These values are crucial for both tuning the launcher trajectory and as input for the satellite's Attitude and Orbit Control System. Noise The instrument module consists of a central structure and three deployable arms. These arms were fol...

Envisat captures first image of Sargassum from space

...Grid computing to broaden this new view. The basic principle behind Grid computing is that anything one computer can do, a pool of computers can do faster and better, enabling the solution of massively complex tasks beyond the capabilities of a single machine or local network. By using Grid technology, Gowe...

How plague-causing bacteria disarm host defense

...post-doctoral researcher in the lab of the study's principle investigator, Jack E. Dixon, Ph.D., professor of Pharmacology and Cellular and Molecular Medicine at the UCSD School of Medicine. Identifying this new target is the first step to developing effective strategies for preventing disease, including m...

Decoding gene expression in cancer tumors using noninvasive imaging

...on May 21 in Nature Biotechnology. According to principle investigator Michael Kuo, M.D., assistant professor of interventional radiology at UCSD, the study represents the convergence of two developing fields of medical research: the mapping of the human genome and advances in diagnostic imaging. The rese...

Natural immune-control system may aid treatment of autoimmune disease and tissue rejection

..." Cantor remarks. "The results serve as a proof of principle that this approach can be applied to the treatment of conditions characterized by an excessive or unwanted immune response." While the work was done with mouse cells, the Qa-1Qdm ligand has the same shape and structure in human and mouse T cells, r...

DNA sieve -- Nanoscale pores can be tiny analysis labs

... PNAS paper is a non-destructive technique that in principle can measure one molecule at a time in a space small enough to fit on a single microchip device. The technique involves creating a lipid bilayer membrane similar to those in living cells, and "drilling" a pore in it with a protein (alpha-hemolysin) pr...

Scientists offer new view of photosynthesis

...hat there must be some sort of underlying physical principle involved," Woodbury said. Not many research groups are equipped to measure the early events in photosynthesis because of the extremely short timescale similar to the amount of time it takes a supercomputer to carry out a single flop. Wang was able...

A matter of force

...ific movements of the mitotic spindle. The same principle might apply also to asymmetric cell division in other organisms and contexts, such as stem cell renewal. The cellular components involved in such divisions have been conserved throughout evolution making it likely that different species might also sh...

Do we need a paradigm change? Disputing coevolution in herbivorous insects

...onstrating a different, perhaps more sophisticated principle of speciation in such diverse groups: phytophagous chrysomelid beetles radiated on a pre-existing diverse resource....

JCI table of contents: April 2, 2007

...adoxical actions of IFN-gamma appear to follow the principle of yin and yang, as do many of nature's paradoxes. That is, the roles of IFN-gamma only exist in a well-defined, integrated system in which the two elements of a proinflammatory process (yang) and an antiinflammatory/regulatory process (yin) interact...

Setting sights on the drugs of the future

...The University of Nottingham is a UK leader. The principle behind targeted therapeutics is to send medicines to the parts of the body where they are most needed, at the right time and in the right dose. In this way, diseased sites can be attacked directly, while healthy cells are bypassed, increasing the eff...

MIT's ocean model captures diversity of underwater forests

...biogeochemical cycles and climate. "The guiding principle of our model is that its ecosystems are allowed to...al selection," said Chisholm. Indeed the guiding principle of the new model is natural selection. It simulates the physical and chemical characteristics of the...

An architectural plan of the cell

...nto a 3D reconstruction on the computer. A similar principle is used to generate brain scans. For the first time they could see directly what previous studies in fission yeast only suggested. In times when a cell is not dividing a microtubule bundle consists of 4-5 individual filaments that are physically con...

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(Date:4/17/2014)... April 17, 2014The development of stem cell therapies to ... to characterize stem cell populations based on cell surface ... a new marker that is highly expressed in a ... blood, which they describe in an article in ... Ann Liebert, Inc., publishers. The article is available free ...
(Date:4/17/2014)... in about one per eight hundred births, Down syndrome ... genetic cause of intellectual disability. It results from a ... third copy of chromosome 21 (1% of the human ... team in the Department of Genetic Medicine and Development ... published in Nature , shed light on how ...
(Date:4/17/2014)... The White House honored Clemson professor Rajendra Singh ... efforts to promote and expand solar deployment in ... the D. Houser Banks Professor of Electrical and ... Silicon Nanoelectronics, is considered a local hero leading ... and economic opportunity in solar power and driving ...
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