Not all embryonic stem cell lines are created equal
...e also able to purify those neurons for study. To probe how the neurons functioned, the researchers developed a culture technique that induced the newly produced neurons to establish synapses with one another. Synapses are the critical junctions between neurons where much of the signaling and communicatio...Unlocking proteins from their cellular shell
...mained static and relaxed. "We were motivated to probe molecular mechanics within cells in part by our recent findings on stem cells that show they generate their own forces, switching on and off development of different cell types," Dennis Discher, professor of chemical and biomolecular engineering at P...New grants bolster efforts to generate faster and cheaper tools for DNA sequencing
...ts along the surface of an Atomic Force Microscope probe tip. This method reduces volume of materials, pote...arallel sequencing platform containing hundreds of probe tips. $100,000 Genome Grants NHGRIs Near-Term Development for Genome Sequencing grants will su...Strains of laboratory mice more varied than previously thought
...llow researchers the opportunity to systematically probe questions within a defined biological system. The mouse is the most popular mammalian model for the study of human disease and normative biology, partly because their genomes are highly conserved. And, since 99 percent of genes in humans have counter...Scientists discover new way to study nanostructures
...n the AC Josephson current, one can also use it to probe mechanical motions of atoms or molecules placed in the junction, said Landman, director of the Center for Computational Materials Science, Regents and Institute professor, and Callaway Chair of Physics at Georgia Tech. The prospect of being able to e...Pediatric ritalin use may affect developing brain, new study suggests
... New York City. The study is among the first to probe the effects of Ritalin (methylphenidate) on the neurochemistry of the developing brain. Between 2 to18 percent of American children are thought to be affected by ADHD, and Ritalin, a stimulant similar to amphetamine and cocaine, remains one of the mo...Molecular detectors may refine cancer treatment
...cular signature of cancer cells. Once an aptamer probe has proved its utility, it can be inexpensively reproduced in a DNA synthesizer. Physical scientists mostly use cultured cellular models to demonstrate a principal, and then we leave the findings behind for the biological scientists to use if they...Researchers discover gene responsible for Restless Legs Syndrome
... This approach allowed Drs. Rye and Stefansson to probe more than 300,000 small regions (single nucleotides) distributed across the entire genome for differences more common to RLS sufferers as compared to population-based controls. According to Dr. Rye, very little is known about the function of the ge...UCLA researchers show that culture influences brain cells
...cospinal excitability (CSE)which scientists use to probe the activity of mirror neurons. They found that the American participants demonstrated higher mirror neuron activity while observing the American making gestures compared to the Nicaraguan. And when the Nicaraguan actor performed American gestures......ife in the underground. These investigations would probe fundamental questions at the crossroads of biology and geology, including whether there are new or very old forms of life underground. Added Lesko, Experiments at SUSEL will also open entire new avenues for basic engineering studies that could exte...American Chemical Society's Weekly PressPac -- June 27/July 3, 2007
... TIME, July 2, 2007 Mercury Excess: Congress, EPA probe possibility of long-term storage of liquid metal This story will be available on July 2 at http://pubs.acs.org/cen/government/85/8527gov1.html FOR ADVANCE INFORMATION, CONTACT: Michael Bernstein ACS News Service Phone: 202-872-6042 Fax: 20...University of Arizona launches major scientific research initiative at Biosphere 2
...on. Biosphere 2 was initially created as a tool to probe the essential environmental questions we must ask in the 21st century, and I look forward with great anticipation to what UA will discover. The controlled-environment facility, 3.14 acres (1.27 hectares) in area, is sealed from the earth below by ...Giant magnetocaloric materials could have large impact on the environment
...rized X-ray beams at the Advanced Photon Source to probe the magnetism of gadolinium and germanium ions as the material underwent its bond-breaking magneto-structural transition. In addition to the expected strong magnetization of gadolinium ions, the researchers found significant magnetization attached to...In nature, proteins sweep up nanoparticles
...atial-resolution imaging tool called secondary ion probe spectrometry, which is located at the Department of Energys Lawrence Livermore National Laboratory. Also called NanoSIMS, the tool determines the quantitative elemental and isotopic composition of a samples surface. To their surprise, they found pr...NIH awards nearly $21 million to fund cutting-edge research equipment
...netic resonance spectrometers will be supported to probe intermolecular interactions at Burnham Institute f...tate field-dependent studies of relaxation used to probe molecular dynamics, supporting investigations of proteins that participate in repair at the sites of...American Chemical Society's Weekly PressPac -- May 30, 2007
...ng nanomaterials may afford great opportunities to probe and manipulate biological processes occurring inside cells, across membranes, and between neighboring cells," their report states. "Our results suggest that the nanowires can be potentially utilized as a powerful tool for studying intra- and inter-ce...Manchester researcher wins Libyan award
...of novel compounds was designed and synthesised to probe the active site constraints of the angiogenic enzyme, thymidine phosphorylase (TP). In work carried out in collaboration with Drs Sally Freeman and Mohammed Jaffar in the School of Pharmacy, Abdul showed that some novel compounds displayed good bindi...MIT researchers probe bones' tiny building blocks
...s of the strength and toughness of a material, you probe it at smaller and smaller length scales," said co-...lecular force probe, which uses an extremely small probe tip to poke out a tiny fragment of bone, Ortiz and colleagues mapped the stiffness of bovine shin bo...Decoding protein structures helps illuminate cause of diabetes
... he adds, "We need tools that not only allow us to probe the molecular structures, but also look at how the structures change in time."Zanni's research group uses a method, known as two-dimensional infrared spectroscopy (2-D IR for short), that takes advantage of the restless nature of molecules and atoms....NASA-funded robotic sub makes final dive to reach bottom of Earth's deepest sinkhole
... depths. Previous expeditions tested the robotic probe that will make the dive. The Deep Phreatic Thermal Explorer, known as DEPTHX, is a tangerine-shaped submarine designed to survey and explore for life in extreme regions on Earth and potentially in outer space. During eight years of research at Zacat...