Protein pulling -- Learning how proteins fold by pulling them apart
...nd graduate student Nolan Harris's new approach to probing these energy states yields something akin to a map of the rollercoaster's path. For example, theirs is the only experimental method that can reveal the slope and height of the energy barrier that the protein must overcome. "Other experimental metho...Bioinformatics-related methods are featured in Cold Spring Harbor Protocols
... interdisciplinary field called bioinformatics. By probing genome sequence data with in silico tools, biologists can infer the functions of specific genes, evaluate the evolutionary relatedness among species, and identify DNA variants that are predictive of disease. This valuable information can both complem...World's first X-ray free electron laser is on course to completion
...acteristics will aid scientists in discovering and probing new states of matter, understanding and following chemical reactions and biological processes in real time, imaging chemical and structural properties of materials on the nanoscale, and many new and exciting discoveries we cannot even imagine today, ...Herpes virus hijacks DNA repair process
June 13, 2007 -- Scientists probing the details of viral infection have discovered an intriguing surprise: in mice, herpes viruses hijack their host cells' tools for fixing DNA damage and use those tools to enhance their own reproduction. The DNA damage response normally fixes DNA err...Primitive yeast yields secrets of human cholesterol and drug metabolism
By first probing the way primitive yeast make cholesterol, a team of scientists has discovered a long-sought protein whose human counterpart controls cholesterol production and potentially drug metabolism. The collaborative study by investigators at Johns Hopkins U...Climate change only one symptom of a stressed planet Earth
...h System. These models will then become useful for probing the other important areas in which human behaviour is changing our Earth and environment, especially those with complex interactions with the climate system. Corinne Le Qur, IPCC WGI Chapter 5 Lead Author (Associate Professor, University of East An...Researchers probe health and safety impacts of nanotechnology
...os, a doctoral student in chemical engineering, is probing the potentially harmful effects of nanotechnology by testing how ultra-small particles may adversely affect living cells, organisms and the environment. But this is no scene from a Michael Crichton's novel "Prey" about nanotechnology run amok. Rather...News tips from ACS Chemical Biology
...at can selectively enter cells are great tools for probing the workings of the cell and for treating disease....he many new techniques available for observing and probing individual molecules. If scientists could precisely understand the response of a cell to a parti...New study sheds light on 'dark states' in DNA
...matter in the universe there was no direct way of probing it. The Ohio State chemists used a technique called transient absorption, which is based on the idea that molecules absorb light at specific wavelengths, and allows them to study events happening in less than a picosecond. They found that DNA dissip...Shotgun sequencing finds nanoorganisms
...Mars. "This community of microbes is relevant to probing potential strategies for life on other planets, especially the life likely to exist on Mars," she said. The organisms in the mine drainage, which live in a pink slick on pools of acidic green water, obtain energy by oxidizing iron - that is, genera...Gene-bender proteins may sway to DNA
... sub-microseconds. It gave us a new time window on probing protein-DNA interactions," Ansari said. That broader time window, obtained in combination with the stopped-flow measurements, provided the first direct observation of DNA bending when bound to a DNA-bending protein. "We found that the time-scales ...Study finds periodontal treatment does not lower preterm birth risk
...ese included the bleeding of gums when probed, the probing depth between the tooth and gum, and measuring tooth attachment. As additional evidence, the researchers found no difference in risk for preterm birth when they compared treatment and control women who had the most extensive bleeding of the gums, a ...Secrets revealed in sequencing of honey bee genome
...ientists at other institutions, have already begun probing the honey bee genome for its many secrets. The primary discoveries found so far are presented in the Oct. 26 issue of Nature, and in other scientific journals. Why sequence the honey bee genome? "Honey bees are the premier pollinators on Earth, and p...Study suggests earlier crop plantings could curb future yields
... temperatures brought on by global warming. But on probing the last 30 years of the climate record, Kucharik found little proof that warmer weather motivated the early plantings. "There is very weak or little to no correlation with springtime temperatures over the majority of the Corn Belt and these [earlie...Cold Spring Harbor Protocols features methods for analyzing protein interactions
...basis of all living organisms, techniques aimed at probing protein interactions have come to the forefront in recent years. The new methods published today by CSH Protocols will be useful for researchers seeking to identify the molecular partners--such as other proteins or DNA--to which specific proteins ...Snap judgments decide a face's character, psychologist finds
... works with a sophisticated technological tool for probing brain activity called a functional magnetic resonance imager (fMRI), and Todorov said some of his general research suggests that the part of the brain that responds directly to fear may be involved in judgments of trustworthiness. "The fear respon...Nano probe may open new window into cell behavior
...x and intricate cellular communication pathways by probing cell activities in the natural cellular environment." The SMS probe offers the capability to gently pull biomolecules (proteins, metabolites, peptides) precisely at a specific point on the cell/tissue surface, ionize these biomolecules and produce ...Long-term changes in experience cause neurons to sprout new long-lasting connections
... "What we think they are doing is reaching out and probing for potential neuronal partners. And while most of them retract, with novel sensory experience some populations of these new spines make connections that constitute beneficial new wiring. So those spines gain bulk and are stabilized as persistent spi...Researchers show how brain decodes complex smells
...nput is smell, sight or sound. Shea suggested that probing the olfactory system could help scientists better understand, for example, how the various biological and neurological components underlying perception formed and evolved....Collaborative study successfully applies neutrons to study hydrogen transfer in biological systems
...ncharged subatomic particles--are another tool for probing biological structures and complements X-ray diffraction and other microscopic studies. However, unlike X-rays, neutron scattering can detect heavy and light elements equally well and even sense vibrations of atoms as well as their positions. An acce...