Blood pressure medication may revolutionize treatment of Marfan syndrome
... Genetically engineered mice are a standard way of probing the developmental function of the genes that have been altered. To help in puzzling through some of the questions that had arisen in Dietz's mind, the scientists first focused on the abnormal lung tissue in the mutant mice. They knew that people wit...Molecule by molecule, new assay shows real-time gene activity
...side -- greatly increases scientists' precision in probing genetic activity. Using the new assay, described this week in the journal Science, researchers led by Harvard's X. Sunney Xie counted, one by one, protein molecules generated in small bursts within cells as multiple ribosomes bound to single copies o...Grand challenge seeks carbon sequestration, hydrogen production solutions
...ef scientists John Zachara and Jim Fredrickson, is probing the fundamental question of how subsurface metal-reducing bacteria interact with and transfer electrons to the mineral surfaces on which they live. Pakrasi spoke Feb. 17, 2007, at the annual meeting of the American Association for the Advancement of ...Another world-record achievement for National High Magnetic Field Laboratory
...rs and microscopes as essential research tools for probing the mysteries of nature. Long used by the physics community to understand the fundamental nature of matter and electronic structures, magnetic fields now are used by biologists, chemists and even pharmacists to better understand complex molecules and...Frog peptides block HIV in lab study
...s." The frog peptides are an exceptional tool for probing "what the virus knows about the dendritic cell that we don't know," Unutmaz added. "How does HIV manage to survive and cycle back and forth to the cell membrane? If we can understand that, we'll find the gaps, and that will open a whole new universe ...Study in Royal Society journal on possiblity of human organ regeneration
...rates of gametocytogenesis in response to mosquito probing by Dr D Shutler, Dr SE Reece, Dr A Mullie, Dr PF Billingsley and Professor AF Read (rspb.2005.3232) The organisms that parasites live in are called hosts, and parasites have some remarkable strategies to move from host to host. Understanding these ...Embryonic stem cells accrue genetic changes
..., or no measurable effect at all. In addition to probing changes in the nuclear and mitochondrial DNA sequences and copy numbers, the researchers examined whether the cells' genetic material had shifts in marks that sit on genes and are passed from cell to cell during cell division. These so-called epigene...Mouse genome much more complex than expected
... from Australia, Asia, Europe and the US have been probing the genome of the mouse in a joint study lasting several years. Their results in some aspects have completely overturned geneticists' traditional assumptions. The findings are available in the prestigious journal Science on 2nd September. The general...How butterflies fly thousands of miles without getting lost revealed by researchers
..., the butterflies lost their orientation Further probing revealed a key wiring connection between the light-detecting navigation sensors in the butterfly's eye and its brain clock Thus, it was shown that input from two interconnected systems UV light detection in the eye and the biological clock in the br...Single cell recognition research at UCLA/Caltech finds a Halle Berry neuron
...ns made in recent years by the UCLA team, which is probing the underpinnings of the human mind at the single neuron level in humans. Two years ago they identified single cells in the human hippocampus specific to places during human navigation. The body of work is an example of the power of neurobiological r...Scripps scientists identify target of an immune suppression molecule called CD22itself
...am's method provides a general approach useful for probing what proteins of interest are interacting on the surfaces of living cells and controlling cell signaling....Scientists team up for multiyear studies of microbial mysteries
...ef scientists John Zachara and Jim Fredrickson, is probing the fundamental question of how subsurface metal-reducing bacteria interact with and transfer electrons to the mineral surfaces on which they live. More than two dozen researchers from 16 institutions will participate in the three- to- five-year stu...For young canaries learning their song, freedom in youth gives way to rules in adulthood
...e comes about. "Canaries seemed good material for probing these questions," says Nottebohm. "The method we chose was to tutor canaries with synthetic computer-generated song that violated a specific 'rule' of adult canary song. Sometimes by trying to see how far you can push an organism to do things it woul...International conference probes the origins of life beyond Earth
...carbon dioxide production; David Deamer, a chemist probing the origins of the genetic code; Doug Lin, a renowned theoretical astrophysicist working on the formation of planets; Karl Stetter of the University of Regensburg, Germany, a pioneer in extremophile research (how bacteria and organisms adapt to extre...A human parasite with a streamlined mitochondrion
...described, and thus it provides a model system for probing which mitochondrial functions are truly essential for eukaryotic cells. Download PDF...Automated imaging screen reveals promising drug candidates
...sed screening to identify small molecules both for probing cell biology and for identifying promising drug candidates....Future diabetes drugs may target new protein interaction
...h closer, says Puigserver. The researchers are now probing the pyruvate-sirtuin1 connection more closely and looking for more details of the sirtuin1-PGC1 interaction. Also on the to-do list: examining sirtuin1 and PGC1 in other tissues, particularly muscle and fat, two other energy-producing tissues in mamm...Gene therapy for Parkinson's disease moves forward in animals
...in Sunnyvale, Calif., who recently chaired a panel probing GDNF experimentation for the Michael J. Fox Foundation for Parkinson's Research. "This is additional experimental evidence that suggests that it can be a promising approach to this disease using in vivo gene therapy, which is very applicable to human...Richard Zare awarded the 2005 Wolf Prize in chemistry
...around two recurrent themes: The use of lasers for probing details of how electrons distribute themselves within atoms and molecules, and hence dictate their chemical properties; and the application of high resolution and ultra-sensitive physical techniques to both biochemical and chemical analysisZare's inv......cal and chemical molecules on the atomic scale and probing the fundamental aspects of atomic structure. Congress began funding project engineering and design work for LCLS in fiscal 2003 with $6 million. Last year, LCLS received $7.5 million for engineering and design, and $2 million for research and develop...