Identification of genetic risk factor for coeliac disease promises improved treatment
...eads to different amounts of these cytokines being produced than in someone with coeliac disease providing defence against intestinal inflammation. Coeliac disease is found in around 1 in 100 of the British population. It is caused by intolerance to gluten - a protein found in wheat, barley and rye - whi...Hormone that signals fullness also curbs fast food consumption and tendency to binge eat
...is the synthetic form of amylin, a satiety hormone produced by the beta cells of the pancreas, which also produce insulin. Satiety hormones are commonly thought to control food intake by signaling to the brain when we are full, said Christian Weyer, M.D., the studys senior author and executive director of c...Lack of sun does not explain low vitamin D in elderly who are overweight
...min D is called the sunshine vitamin because it is produced by the body when the skin is exposed to ultraviolet (UV) rays from the sun. Vitamin D can also be obtained from foods such as fish and fortified milk and from supplements. When this fat-soluble vitamin enters the body it is converted in the liver to ...Satellite images show destroyed and threatened villages in Darfur
...ondon and the Zimbabwe Lawyers for Human Rights -- produced satellite images showing strong evidence the government of Zimbabwe had destroyed a settlement west of Harare and relocated thousands of residents as part of a political campaign against opponents. For the Eyes on Darfur project, Amnesty Intern...Organic Food Miles take toll on environment
... recommends that shoppers switch to buying locally produced food at grocery stores or farmers markets when possible, and that any future government policy on the environment should consider the reduction of CO2 emissions associated with food transport. The study also found that a large gap between total costs...New clues to stroke role in Alzheimer's
...The researchers discovered that particular enzymes produced during brain injury, called caspases, somehow also enable BACE to linger in brain cells. Caspases are so-called executioner enzymes that destroy brain cells such as those damaged by oxygen deprivation during stroke. In further exploring the link be...Research team identifies new Alzheimer's gene
...from Alzheimers patients and that the GAB2 protein produced by this gene is present in those brain cells conta...metrix 500K Arrays, the studys researchers rapidly produced a genetic map of each brain tissue sample and isolated the GAB2 gene relatively quickly. This Alz...Other highlights from the June 6 JNCI
...rs generated from these cells grew more slowly and produced fewer metastates. The ubiquitous expression of integrin 7 in human organs and widespread mutations of this gene in human cancers raise the possibility that integrin 7 may have a role in the development of many human malignancies, the authors write....What's going on in the body? Advanced time-of-flight PET takes a superior 'look'
...PET scanners create images by detecting gamma rays produced by a radioisotope after it is administered to a patient. Conventional scans track where the rays go, but they don't take into consideration the precise time it takes for each ray to reach the PET detector. TOF/PET scanners measure this time differenc...JCI table of contents -- June 1, 2007
...rved in patients with HBIM a mutation in Gne/Mnk produced lower amounts of sialic acid, had blood and excess protein levels in their urine, and had structural defects in the glomerulus (a bundle of capillaries in the kidney that are actively involved in the filtration of blood). The authors show that these ...Scientists develop new drugs to fight colon and breast cancer more effectively
...s, which enables the identification of the effects produced by drugs on each gene the lowest and most specific level that Medicine can deal with. Our research, says Caba Prez, has been conducted with absolute precision with the aim of obtaining the lowest possible concentration of drug producing the most s...Recycled garden compost reduces phosphorus in soils
...ith compost made from recycled garden offcuts have produced equivalent yields to those cultivated by conventional farm practice, but without the subsequent build up of phosphorus. NSW Department of Primary Industries (DPI) scientists have found very high levels of phosphorus and low levels of organic carbon...Scientists honored with 'Excellence in Clinical Research Award'
...which moved rapidly into human clinical trials and produced promising results. JDRF funding is now accelerating a second-generation version of this drug into Phase II clinical trials. Dr. Brand received his M.D. and Ph.D. from the University of Western Australia. Tony Cruz, Ph.D., a scientist and entrepren...Research identifies protein that signals flowering in squash plants
...lowering-inducing substance, known as florigen, is produced in the leaves of a plant under inducing conditions, and then is transported through the phloem to the floral meristems, where it acts together with other factors to induce flowering. The precise nature of the florigenic signal has eluded plant biolog...Existence of muscle-building stem cells points to regenerative therapies for muscular disease
...seen among stem cells. That lopsided cell division produced one "daughter" like its parent, exhibiting a stem cell-like capacity for self renewal, and another Myf-5 positive cell. The researchers also showed that satellite cells in which Myf-5 was switched on, when injected into the muscles of mice, continu...New study suggests potential for a broadly-protective HIV vaccine
...ectivity of a variety of HIV-1 strains. Antibodies produced as a result of immunization neutralized all 48 strains of HIV-1 tested. The results are encouraging for vaccine development, because they showed that it is possible to elicit a broad-spectrum antibody response....Yin and yang -- Balance could play key role in progression of Alzheimer's disease
... ancient Chinese philosophy. When the peptides are produced in the correct proportions, the brain is healthy; but when that delicate balance is changed, pathological changes will occur in the brain and the persons memories become hazy, leading to eventual dementia." Wang expects that this imbalance could b...Story ideas from the Journal of Lipid Research
...dicating that these ABC proteins may be abnormally produced in the affected individuals. Article: " Common ...s higher than it should be and too much insulin is produced to counter this blood sugar increase. Patients with this disease have increased levels of triglyceri...New research shows sharks use their noses and bodies to locate smells
...ith one or the other flavored with food odor. This produced four separate smell targets for the sharks to locate. "In addition, we also tested the sharks under two light conditions fluorescent and infrared and in two sensory conditions with their lateral lines intact or lesioned by streptomycin," explai...Growth factors and environment combine to increase brain maturation
...the accelerated maturation of cortical development produced by enriched environment. The present work suggests that IGF-1 action in mediating the effects produced by environmental enrichment on visual system could be exerted through an accelerated maturation of i...