MIT-led team uncovers malaria mechanism
... in the early stages of that process. The parasite produces RESA during the first stage of malaria (known as t...ed the parasite and then knocked out the gene that produces RESA and then measured the red blood cells' deformability with "optical tweezers," which use lasers ...Botulism bug has few genome wrinkles
The genome of the organism that produces the world's most lethal toxin is revealed today. This toxin is the one real weapon in the genome of Clostridium botulinum and less than 2 kg - the weight of two bags of sugar - is enough to kill every person on the planet. Very small amounts of the s...Parkinson's protein protects neurons from stress induced cell death
...Substantia Nigra, a structure in the midbrain that produces dopamine. The resulting deprivation of this messenger substance causes symptoms like muscular tremor at rest and restricted mobility and even complete immobility. Characteristic deposits are found in the brain, the Lewy corpuscles. Little is known...Repair of DNA by Brca2 gene prevents medulloblastoma
...plexity before and shortly after birth, it rapidly produces many new nerve cells. "Our study showed that the Brca2 gene acts as a surveillance mechanism that triggers repair of DNA that is damaged when the cell makes a duplicate set of its chromosomes each time it divides," said Peter McKinnon, Ph.D., asso...Newly identified mechanism for silencing genes points to possible anti-cancer strategies
... mechanism that blocks the cellular machinery that produces protein from messenger RNA." In earlier studies, Shiekhattar identified a three-molecule complex known as RISC and showed that it plays a vital role in generating microRNAs. In the current study, Shiekhattar and his colleagues extended those studie...Scientists seek useful traits in wild cottons
...s by killing the wheat with herbicide. "This produces massive thrips pressure on the cotton plants, and results in a lot of damage to those first four true seedling leaves," he said. "We measure the leaf damage, identify cottons that show thrips resistance and subject those to further tests." She...Dinosaur hearing, listening to muscle noise, quieter cubicles
...trument's bore, the chamber where air vibrates and produces pitch. Wilfried Kausel of the University of Music and Performing Arts in Austria ( kausel@mdw.ac.at ) will present growing experimental evidence that wall vibrations and thickness are important (4pMU2). REDUCING NOISE IN MRI SCANNERS Magnetic ...Thale cress goes on the defensive
... acid, ethylene, and salicylic acid that the plant produces as a response, was specific for each pest. Analysis of the activated genes made it clear that every hormone composition in the plant led to an extremely complex expression file. Four pests mainly stimulated the production of the plant hormone jasm...LIAI scientists make important finding on cytomegalovirus transmission
...affects the majority of the worlds population, but produces little or no symptoms in healthy individuals. However, it can cause multi-organ disease in newborns or persons who are immuno-compromised such as organ transplant recipients or AIDS patients. Ware said, "The main importance of these experiments is...Research suggests men's sexual behavior adapts to perceived threats
...tations, sexual conflict between males and females produces a co-evolutionary arms race between the sexes, in which an advantage gained by one sex selects for counter-adaptations in the other sex."...Molecule that destroys bone also protects it, new research shows
...05 with the discovery of a new type of T cell that produces IL-17, now called TH-17," she said. "We know now that almost all autoimmune diseases, at least in the mouse model, are caused by TH-17 cells. This new information has forced scientists to revise completely how they view their favorite disease. Every...Genetic roots of bipolar disorder revealed by first genome-wide study of illness
...hought to exert its therapeutic effects. The gene produces an enzyme (diacylglycerol kinase eta) that functions at a point closer to the root of the lithium-sensitive pathway than does the protein that lithium is thought to target. Scientists can now try to develop more effective medications by focusing on ...Story ideas from the Journal of Lipid Research
... AD. One of those genes has already been found: It produces a protein called amyloid precursor protein (APP) t...gues have found another gene on chromosome 21 that produces a protein that regulates the amount of cholesterol present in a cell. The scientists showed that thi...Use of wind energy in US growing, but planning and guidelines are lacking
...t of using wind to generate electricity is that it produces no carbon dioxide (CO2), a major greenhouse gas, or any other air pollutant. Based on U.S. Department of Energy projections for wind-energy development in the United States, the committee estimated that by 2020, wind energy will offset approximately...Scientists discover rare 'gene-for-gene' interaction that helps bacteria kill their host
...melanin. The researchers found that Photorhabdus produces a special phenoloxidase inhibitor to protect itsel...is molecule is also an antibiotic and Photorhabdus produces it to kill off other microbes that might grow in the corpse of the dead insect. To test their fin...Generic biologic drugs unlikely to offer significant savings
...omics. The research was funded by Genentech, which produces biologics. In order to predict prices of generic biologics, the researchers combined a theoretical model of generic biologics with historical data from the generic pharmaceutical market. Generic pharmaceutical products are widely accepted as a le...News tips from the Journal of Neuroscience
...d the thalamic nuclei in which damage specifically produces allodynia, a painful response to normally innocuous mechanical or cold stimuli. The subjects had experienced small thalamic strokes. The authors used somatosensory testing and atlas-based mapping with positron emission tomography and magnetic resonan...Enhanced environment restores memory in mice with neurodegeneration
...ses. Once activated in the mice, the p25 transgene produces neural pathology very similar to that of patients with Alzheimer's disease, said Tsai. The animals show brain atrophy and loss of neurons due to the same kind of cellular abnormalities seen in people who have Alzheimer's disease, she said. Researche...Satellites shed light on global warming
...ng," Llewellyn-Jones said. "The ATSR instrument produces data of unrivalled accuracy on account of its unique dual view of the Earths surface, whereby each part of the surface is viewed twice, through two different atmospheric paths," Llewellyn-Jones added. "This not only enables scientists to correct for ...Pioneering research on sleeping sickness wins MERIAL Award for Parasitology
...rosis Factor) plays in sleeping sickness. Our body produces TNF as a protection against a number of micro-organisms. About 20 years ago, scientists discovered that animals that have been infected with African trypanosoma produce far too much TNF. Through his research, Stefan Magez has shown that a trypanosoma...