Huntington's disease study shows animal models on target
...usion, the scientists measured the gene expression profile of seven different transgenic mouse models of HD, representing different conditions and disease stages. These profiles clarified the role of different forms and dosages of the protein hungtintin in the transcriptional activity of neurons. They then d...N.C. A&T food scientist develops process for allergen-free peanuts
...ood. Their rich flavor, nutrition, fat and protein profile makes for a nearly perfect food from a food processing standpoint as well. From his lab at Tuskeegee University in the early 1900s, the famed agricultural chemist George Washington Carver discovered approximately 300 food and non-food products fr...Purdue-IU researchers explore new method for early disease diagnosis
...ible, Raftery said. "This technique allows us to profile a class of biomarkers - molecules that indicate di...ress or a specific disease state. "The metabolic profile in biofluids, such as blood and urine, provides a snapshot of ongoing biological processes in the hu...QUT's top researchers honored with fellowships
...etic screening with a person's demographic history profile to more accurately identify individuals at risk of developing schizophrenia and provide early intervention. "Early intervention of schizophrenia would significantly reduce the burden to Queensland's health care system and increase the likelihood of...The Cancer Genome Atlas awards funds for technology development
...pes of cancer likely will have a different genomic profile or set of profiles. We urgently need tools equal to this task, said NHGRI Director Francis S. Collins, M.D., Ph.D., whose institute led the NIH component of the Human Genome Project. One of the major lessons we learned from the Human Genome Project i...Support for chromosomal theory of cancer found in cancers' development of drug resistance
... have found, for example, that the gene expression profile of a breast cancer cell can tell them which treatments work best. This indicates, Duesberg said, that chromosomal disruption, which affects the expression of thousands of genes, is a better explanation for the cause of breast cancer than is the mutat...Gut check: Tracking the ecosystem within us
...f thousands of genes. The team used microarrays to profile the mixture of bacterial DNA in an average of 26 s...robial communities converged toward a more generic profile characteristic of the adult intestine. The new study, the authors noted, might bring some clarity...UN issues analysis of global investors' sustainable energy 'gold rush'
... more technology and private investment (with high profile investment interest shown in biofuels during 2006 by entrepreneurs such as Vinod Khosla, Bill Gates and Richard Branson). Europes publicly quoted companies attracted the most public stock market investment dollars: $5.7 billion compared to $3.5 bill...Staphylococcus aureus hides out in cells
...ered the lung cells, the bacterias gene expression profile dramatically changed: gene expression for bacterial metabolic functions and transport shut down, putting the bacteria in a dormant state. Simultaneously, production of toxins potentially lethal for the epithelial cells becomes strictly controlled to ...Latest data shows MabThera provides significant, sustained relief from symptoms of RA
...nts achieving remission1. Importantly, the safety profile of MabThera remained unchanged in patients who had...Thera when used long-term revealed that the safety profile of MabThera remained consistent with a low, unchanging rate of serious infections in 1053 patients, ...Interim analysis of anti-cancer vaccine, BiovaxID, to be conducted
...dependent confirmation of BiovaxIDs overall safety profile in its ongoing Phase 3 Clinical Trial. We are committed to getting BiovaxID to NHL patients as soon as possible. The support being offered by the DMC in upcoming discussions with the FDA and EMEA is of the utmost importance in achieving this goal....2007 Image of the Year: Molecular imaging relates human brain chemistry to aggressive behavior
...ough the personality questionnaire gave a complete profile of the mens personalities, only aggressive personality was related to brain MAO A activitynot other personality dimensions, she emphasized. Our finding corroborates the relevance of brain MAO A in aggressive personality, explained Alia-Klein. If th...ChemGenex reports successful personalized dosing of Quinamed at ASCO
...has been hampered by the unpredictable side effect profile for patients said Dr Kuhn. We are excited by the new opportunities that personalized dosing of Quinamed offers for a range of solid tumor patients who have developed resistance to existing therapies. Highlights of the presentation included: Conf...Depiction of findings selected as '2007 Image of the Year' by Society for Nuclear Medicine
...estionnaire, which gave the researchers a complete profile of the mens personalities, not merely their tendency toward aggression. The main finding: The lower the subjects brain MAO A activity levels, the more they answered yes to statements about taking advantage of others, causing them discomfort, having...Genomic signatures identify targeted therapies for lung cancer
... alive in laboratory cultures to produce a genomic profile of the tumor's molecular makeup. These patterns led to the identification of defective pathway in patients with both early stage and advanced disease. In particular, tumors with defects in two specific pathways -- called Src and Myc -- had much worse...Gene expression patterns predict rapid decline in idiopathic pulmonary fibrosis patients
... ONE, a subset of patients with a specific genetic profile has a much more rapid progression to complete pulmonary failure and death without a lung transplant. Based on observations in the clinic that some IPF patients display a more rapidly progressing disease course, researchers at the Simmons Center for......ta have not previously been available, as the soil profile was destroyed using conventional sampling procedures. This has changed thanks to the new soil retriever: the soil core is first loosened from the walls of the lysimeter and then cut into ring segments of the desired size that can be examined one by o...Tiny genes may increase cancer susceptibility, Jefferson scientists find
...e ways that MiRNAs are expressed have been used to profile tumor types in humans. To see if miRNAs could affect cancer risk, Linda Siracusa, Ph.D., associate professor of microbiology and immunology at Jefferson Medical College of Thomas Jefferson University, research associate Cinzia Sevignani, Ph.D., an...IMS updated recommendations on postmenopausal hormone therapy
...ctors for cardiovascular disease such as the lipid profile and metabolic syndrome. In women less than 60 ye...years old should not be concerned about the safety profile of HT. New data and re-analyses of older studies by womens age show that, for most women, the potent...