Liver transplant patients gain same benefits from CellCept as kidney transplant patients
...teroids are known to have a negative impact on the progression of HCV, which can result in liver fibrosis (Abstract 475) Optimal kidney function CellCept taken with a low dose of tacrolimus showed a trend towards improved kidney function (Abstract 1240). CellCept is proven to promote excellent kidney functio...Applied NeuroSolutions biomarker may predict Alzheimer's disease progression
...231) may be used to effectively predict structural progression of Alzheimer's disease." Harald Hampel, M.D., of t...nts, thus, p-tau 231 levels may be used to predict progression of brain atrophy in AD patients. In the study of 22 Alzheimer's disease patients, all underwent Magn...New understanding of DNA repair may pave way to cancer treatments
... ATF2 has an important role in the development and progression of melanoma tumors. Inhibition of ATF2 was found to sensitize melanoma to various treatments, both in tissue culture and in animal models. "Melanoma is usually resistant to chemotherapy, but we found that by inhibiting ATF2, it became more sensitiv...Other highlights in the June 1 JNCI
...ly dysplastic lesions have a greater potential for progression to invasive colorectal carcinoma than lesions with less dysplasia, this finding warrants further investigation in future chemoprevention trials of UDCA in this population," the authors write. Contact: Donna Breckenridge, Communications, Arizona Cance...Eleven gene 'signature' reliably predicts cancer prognosis
...t these tumor stem cells are responsible for tumor progression and metastasis. In a revolutionary study appearing in the June 1 print issue of The Journal of Clinical Investigation, Gennadi Glinsky and colleagues from the Sidney Kimmel Cancer Center evaluated 1122 cancer patients diagnosed with 10 different typ...JCI table of contents June 1, 2005
...t these tumor stem cells are responsible for tumor progression and metastasis. In a revolutionary study appearing in the June 1 print issue of The Journal of Clinical Investigation , Gennadi Glinsky and colleagues from the Sidney Kimmel Cancer Center evaluated 1122 cancer patients diagnosed with 10 different t...JCI table of contents July 1, 2005
...rsity of Calgary show that, in diabetic mice, this progression is accompanied by an increase in the frequency of ...turation response advance our understanding of the progression of autoimmune diabetes. Title: Developmental control of CD8+ T-cell avidity maturation in autoimmun...From sound analysis to nicotine addiction
..."Mechanisms of tumour-vessel interaction in tumour progression and metastasis" aims to bring together the best research groups working in this field in Germany. Conventional findings on vascular endothelial growth factor (VEGF) will be subjected to state of the art analysis and promising new methods used in orde...Royal Society elects Tom Curran as Fellow
...ession is a critical factor in the development and progression of cancer. Early in his career, Dr. Curran discovered the fos oncogene and demonstrated its function in gene regulation. He then illustrated how the activity of nerves in the brain can affect the function of fos. This groundbreaking discovery helped...Suppressing growth hormone in early adulthood may prevent cancer
...eginning in early adulthood may delay the onset or progression of several types of cancer, researchers from Wake Forest University School of Medicine and other centers reported today at ENDO 2005, the annual meeting of the Endocrine Society, in San Diego. Suppression of growth hormone and insulin-like growth fac...Temple virologist receives $6.1 million NIH grant for neuro-AIDS research
...rstand the molecular basis for the development and progression of neurological diseases that occur in some AIDS patients." Khalili, who recently received Temple's Faculty Research Award, said that HIV can trigger the JC virus, which causes the fatal demyelinating disease Progressive Multifocal Leukoencephalopat...Joslin scientists confirm link between PKC enzyme and kidney disease in diabetes
... PKC-beta 2 isoform plays an important role in the progression of diabetic kidney disease. To test this hypothesi...ional screening and diagnostic tests to assess the progression of kidney disease in each model. In diabetes, hyperglycemia overactivates PKC-beta and gradually da...Engineered skin offers clues to melanoma development
... cell division. This enzyme is associated with the progression of many cancers. None of these mutant genes, when introduced individually or in combination, led to cancerous growth. But when a mutant form of Ras--produced by an oncogene that sends growth signals to a cell--was added to this combination, it produc...Physical and functional interaction of key cell growth molecules linked to cancer
...g of the role of the EGFR signaling pathway in the progression of cancer will be useful for development of new anticancer therapeutics. In the current study, Dr. Mien-Chie Hung and colleagues from the Department of Molecular and Cellular Oncology at the University of Texas M.D. Anderson Cancer Center found that ...Columbia University launches multi-year campaign to support stem cell research
...ts regarding mechanisms that control the onset and progression of disease. Stem cells will also be useful as targets in drug discovery. Current stem cell research projects at CUMC include: Examining the development, function and survival of dopamine neurons, which are lost in patients with Parkinson's diseas...Allergies affect 15 million people in UK, says Professor
...luating approaches which may prevent the onset and progression of allergic disorders, developing undergraduate and postgraduate training opportunities for primary care health professionals, introducing regional GPs with specialist interests in allergy and developing a national centre of excellence for research a...Claudin-1: A potential biomarker for colon cancer progression
...xploited as a potential biomarker for colon cancer progression and may also provide new opportunities for therapeutic intervention....JCI table of contents, July 1, 2005
... Claudin-1: a potential biomarker for colon cancer progression Disruption of proteins expressed at the juncture...xploited as a potential biomarker for colon cancer progression and may also provide new opportunities for therapeutic invention. TITLE: Claudin-1 regulates cellul...Most common lung cancers may begin in newly discovered cells
...c and graduate student in Jacks's lab to study the progression of lung cancer and the effects of conventional and experimental therapies. The mouse carries a silent genetic mutation of an oncogene known as K-ras, which is found in about one-third of all tested non-small cell lung cancers in people. A specially ...SNM member David James Brooks receives 2005 Kuhl-Lassen Award for research in brain imaging
.... Brooks's research includes information about the progression of disease, primary mechanisms of onset and progre...nd brain activation changes associated with onset, progression and treatment complications of Parkinson's and Huntington's diseases; and the effects of putative ne...