A means to an end: Telomere maintenance and bone marrow failure
...isease, dyskeratosis congenita (DC). DC is a rare, progressive bone marrow failure syndrome that is fatal early on in life. Working with cells derived from DC patients, Drs. Wong and Collins demonstrate that X-linked DC cells are unable to renew themselves because they cannot maintain sufficiently long telomeres...Resistance to chemotherapy in lung cancer, optimizing flu vaccination strategies
...chdogs for human rights, and as advocates for more progressive policies on behaviour change," they say," it is the public sector that has the primary responsibility, and capability, for establishing policy, regulation, accountability, strategy and, by and large, the bulk of service delivery. It is thus essential...Researchers receive $12.8 million NIH grant to improve diagnosis/treatment of chronic lung disease
...developed mostly by CF patients, Kolls said. CF is progressive and attacks the lungs. The disease affects more th... Fibrosis (IPF). IPF is a disease characterized by progressive scarring of the lung without any recognizable reason. The disease affects more than 100,000 patients...Acorda announces positive Phase 3 Fampridine-SR study in people with multiple sclerosis
...About MS Multiple sclerosis is a chronic, usually progressive disease of the central nervous system in which the immune system attacks and destroys the structure, and therefore degrades the function, of nerve cells. Approximately 400,000 Americans have MS, and every week about 200 people are newly diagnosed. Mo...Roger Kornberg to present Dickson Prize lecture at U of Pittsburgh's SCIENCE2006: Feel the Power
... recognizes individuals who have made significant, progressive contributions to the field of medicine. Established in 1969 by the estates of Joseph Z. Dickson, M.D., and his wife, Agnes Fischer Dickson, the prize consists of a bronze medal and an award of $50,000. Dr. Kornberg's presentation, titled "Chromatin ...Handling HPV vaccines and screening: The views of 100 authors
...of the Human Papillomavirus (HPV) vaccines and the progressive introduction of HPV-based screening technology, the field of cervical cancer prevention is expanding into new areas of influence involving an ever-widening group of professionals. Starting with the offer of HPV vaccines to pre-adolescent girls and th...Mars mission Risk 29: Scientists research ways to reduce radiation-induced brain damage
...for conditions like Alzheimer's disease that cause progressive dementia. The projects of the twelve teams investigating the cosmic radiation risks, listed by principal investigator, are: Edouard Azzam, University of Medicine and Dentistry of New Jersey, Newark, N.J., the role of gap-junction communicati...Experimental cancer drugs counter muscle deterioration seen in muscular dystrophy
...of more than 30 genetic diseases, characterized by progressive weakness and deterioration of skeletal muscles. All are inherited, caused by a mutation in one of a group of genes responsible for maintaining muscle integrity. Puri's team studied the disease's most common form, Duchenne muscular dystrophy, which af...Pre-clinical study finds Parkinson's cell death blocked by stopping inflammatory factor
...that TNF-dependent inflammation may be part of the progressive features of Parkinson's disease, and this gives us an opportunity with anti-TNF therapy to slow down or prevent the progression of the disease," said Dr. Mal Tansey, assistant professor of physiology at UT Southwestern and senior author of the study....Other highlights in the September 6 JNCI
...ession profile identifies children at high risk of progressive metastatic neuroblastoma, which lacks multiple copies of the MYCN gene. Neuroblastoma, a tumor of the sympathetic nervous system, is the most common solid tumor in children outside the brain. When metastatic neuroblastomas have multiple copies of a ...Chimpanzees can transmit cultural behavior to multiple 'generations'
...ctivity through imaging; increase understanding of progressive illnesses such as Parkinson's and Alzheimers; unlock the secrets of memory; determine behavioral effects of hormone replacement therapy; address vision disorders; and advance knowledge about the evolutionary links between biology and behavior....Toxic molecule may cause most common type of muscular dystrophy
...lar dystrophy (MMD). The disease can cause a slow, progressive wasting of the muscles, irregular heartbeat, cataracts and insulin resistance. Many people don't know they have MMD until their teens or twenties. To prove the theory that toxic RNA is involved in myotonic muscular dystrophy, a research team led...Genetic clues to cardiomyopathy's origins revealed in mice
...Right Ventricular Cardiomyopathy (ARVC) is a rare, progressive condition that causes diseased heart muscle and impairs cardiac function. In many cases, ARVC leads to fatigue, irregular heartbeat (arrhythmia), and, potentially, heart failure and sudden cardiac death. In a previous study, Towbin and colleagues ...Contagious cancer in dogs confirmed; origins traced to wolves centuries ago
...tumor clones--bears "no evidence of genome loss or progressive instability." The findings challenge the idea that there is "an inevitable progression of cancer towards more instability," Weiss said. The study also raises important issues for conservation biology, said Elaine Ostrander in an accompanying prev...New study reveals Rett syndrome can strike males
...should be considered in some baby boys who develop progressive serious neurological problems. "The common think...ed early in life with a severe clinical picture of progressive neurological decline and breathing abnormalities starting soon after birth. All but two had a famil...Miscarriage significantly associated with increasing paternal age
...led to clarify whether there is a cut-off age or a progressive trend over the whole range of ages." The study findings generate strong support for the association of increasing paternal age with increasing rates of spontaneous abortion, and are corroborated by other published studies. "Advanced paternal age m......in transitions from scalloped, to wavy, to smooth; progressive exclusion of the supraoccipital from the foramen magnum; internal hollowing at the base of the postorbital horns; closure of the midline nasal suture; fusion of the epinasal onto the nasals; and epinasal expansion into a morphologically variable nasa...New discovery about Parkinson's at the Montreal Neurological Institute
...ut Parkinson's Parkinson's disease is a chronic, progressive disorder of the central nervous system that belongs to a group of conditions called motor system disorders. Symptoms of Parkinson's, which often appear gradually yet with increasing severity, may include tremors or trembling; difficulty maintainin...Preventing ventilation induced lung injury depends on giving the right number of 'sighs'
...ct against VILI. But low tidal volumes can lead to progressive closure of the lungs' air cells, called alveoli, reducing the lung's ability to exchange gases. One way to reverse closure of the alveoli is to periodically give a more robust puff of air, known as deep inflation. A new study in the online edition ...Discovery of agile molecular motors could aid in treating motor neuron diseases
...n diseases. Motor neuron diseases are a group of progressive neurological disorders that destroy motor neurons, the cells that control voluntary muscles for such activities as speaking, walking, breathing, and swallowing. When these neurons die, the muscle itself atrophies. A well-known motor neuron disease is...