Tag: "proteins" at biology news
Jan Lwe awarded 2007 EMBO Gold Medal
...ark work elucidating the structure and function of proteins
involved in bacterial cell division, said EMBO Executive Director, Hermann Bujard. Awarded annually, the EMBO Gold Medal recognises outstanding contributions of young researchers in the molecular life sciences. Considered the most prestigious award...
Research shows NPD1 protects a key component of vision
...SC scientists discovered that neurotrophins (small proteins
critical in cell survival and death) trigger NPD1 ...ge is maintained by NPD1. The regulation of these proteins
involved in cell survival or death shown by this research will help us define NPD1 survival bioactiv...
After a decades-long search, scientists identify new genetic risk factors for multiple sclerosis
...Ps in two genes that encode interleukin receptors, proteins
that serve as antennae on the surface of immune ce...for some of this genetic susceptibility. HLAs are proteins
displayed on all the body's cells to help the immune system distinguish self from non-self. A varia...
Gene expression pattern could lead to improved treatment of pediatric septic shock
...with the decreased expression of genes that encode proteins
involved in zinc regulation. This unexpected finding suggests these proteins
and zinc regulation could provide a target for therapeutic intervention to inhibit septic shocks pro...
New target for HIV/AIDS drugs and vaccine discovered
...s to prevent infection. It has been known that HIV proteins
disable the antibody-forming part of the immune sy...ngs also raise another intriguing possibility: Nef proteins
may be able to boost or suppress DC and NK cell activity. If so, it may prove to be a valuable new t...
JCI table of contents -- July 26, 2007
...rses atherosclerosis In animals and humans, the proteins
known as liver X receptors (LXRs) sense cholesterol levels. Upon sensing increases in cholesterol, these receptors activate signaling pathways that remove diet-derived cholesterol from the body. Two types of LXRs LXR-alpha and LXR-beta are therefor...
...nd in what regions. The light given off by these proteins
is scattered in the tissue, however, reducing the ...tion of many images. An alternative to fluorescent proteins
is reporters that would be detectable via magnetic resonance imaging (MRI). But for most of the cand...
Can the tonsils influence oral HIV transmission?
...cted by their thickened exterior and the defensive proteins
present in saliva, it is speculated that a low num...lso higher in the tonsils. However, when antiviral proteins
were examined, lower levels of SLPI (secretory leukocyte protease inhibitor), defensins, and thrombo...
Hepatitis C helicase unwinds DNA in a spring-loaded, 3-step process
...case must also navigate around a lot of obstacles: proteins
and other co-factors that are involved in replication. This requires extra energy. Ha compared the energy needs of the NS3 helicase to those of a sport utility vehicle. Its not fuel efficient but in principle it could also go off-road, carry some l...
MicroRNA works with Ago2 protein to regulate blood cell development
...bind to messenger RNAs (mRNAs) the blueprints for proteins
and either target them for destruction or inhibit...n Ago2, the only member of the Argonaute family of proteins
that has a slicer function: That is, once microRNA binds with its target, it cleaves it, effectively...
Carnegie Mellon scientists find key HIV protein makes cell membranes bend more easily
...er via small, membrane-bound vesicles that contain proteins
or other molecular cargo. When delivering their go...f gp41, which in turn drives uptake of HIV RNA and proteins
by the T cell. But the Carnegie Mellon work suggests that FP-23 plays another, equally important fun...
Call for EU to launch major project to map out all our proteins
...ar idea how many active genes there are coding for proteins
in humans and other organisms, even though for som.... The field of proteomics aims to discover all the proteins
produced by a given organism. Such a proteome map would bring the possibility of deducing the precis...
Scratch no more: Gene for itch sensation discovered
...ional itch receptors," Chen says. "We know of some proteins
that are similar to GRPR, so now we're trying to determine if there is functional redundancy in the itching pathway." GRPR knockout mice had normal reactions to painful stimuli, indicating that pain and itch are mediated by separate sets of genes in ...
Steroids, not songs, spur growth of brain regions in sparrows
... perhaps we could use neutrophins, growth-inducing proteins
whose synthesis by brain neurons is stimulated by testosterone. In sparrows, brain areas are directly stimulated by these hormones to grow and one day such hormones might possibly help repair brain damage caused by strokes or neurodegenerative disea...
UB scientist discovers novel iron-copper alliance
...l concentrate on understanding the role of two key proteins
encoded by these genes: an intestinal iron transporter called divalent metal transporter 1 (Dmt1) and an intestinal copper transporter, the Menkes copper ATPase (Atp7a). The overall goal of the project is to answer three specific questions regarding...
Limpets reveal possible fate of cold-blooded Antarctic animals
...ory aquarium reveal that these animals cannot make proteins
the building blocks of growth - efficiently. Le...tropical water limpets typically retain 70% of the proteins
they make, those in the Antarctic appear only to retain about 20%....
Nicotine rush hinges on sugar in neurons
...le deep in the receptors core significant because proteins
normally are filled with hydrophobic (water repell...lubricant. Previously studied homologs of nAChR proteins
that share its structure but not its signaling function are entirely hydrophobic, Chen said, suppor...
New clue into how diet and exercise enhance longevity
...insulin and insulin-like growth factor-1 switch on proteins
inside the cell called insulin receptor substrates (Irs). Other researchers had shown that reducing the activity of the pathway in roundworms and fruitflies extends lifespan. Despite those tantalizing clues, White said, The idea that insulin reduces...
Molecular detectors may refine cancer treatment
...called aptamers to seek out and bind with specific proteins
in body fluids. UF scientists designed the aptam...Current tests to diagnose leukemia use antibodies, proteins
that have the ability to identify harmful substances. But such methods do not capture subtle varianc...
Mucins stand guard against gut infections
Mucins are large proteins
that are secreted on the surface of the gut, and w...omponent of mucosal defense, and the role of these proteins
in epithelial infections and inflammatory disease should be further examined. ...
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