NJIT stem cell researcher to receive research award from biomedical group
...her paper in the Journal of Bone and Joint Surgery proving that adult stem cells taken from one patient can be successfully implanted in another. Researchers originally thought such a transfer might be rejected. And it's not just defective bones that may be regenerated by stem cells and biomaterials. Arinzeh...JCI table of contents, November 15 2004
... underlies type 2 segmental Hailey-Hailey disease, proving molecular confirmation of a novel genetic concept. AUTHOR CONTACT:Jorge Frank Department of Dermatology and Allergology, University Clinic of the RWTH, Aachen, Germany. Phone: 49-241-808-9162; Fax: 49-241-808-2413; E-mail: jfrank@ukaachen.de . ......s were detected as expected in RET-positive cells, proving that the conditional expression scheme had worked. Analysis of individual regions known to be susceptible developmental failure on loss of GFR1 function, such as the kidneys, motor and enteric neurons and certain parts of the central nervous system ...Researchers reconstruct parts of the genome of a common mammalian ancestor
...terested in," he said. The tool is already proving valuable to Haussler's group, which has done comparisons of modern species with their common ancestor, and turned up differences in the rates of genetic change among lineages. For instance, about 22 percent of the human genome consists of new DNA ins...New approach studying protein structure could advance drug development
...d to those documented from the crystal structures, proving the observations were real and validating the method as a potential drug discovery tool. The other author on the report, in addition to Fischetti, Rodi and Makowski is David B. Gore (BioCAT, Advanced Photon Source, Argonne). The researchers have subm...Your brain and you: Forecasting the ethical challenges ahead for neuroscience and society
...ted ethical challenges - the early 21st century is proving to be for neuroscience," said Farah, a professor in Penn's Department of Psychology and director of Penn's Center for Cognitive Neuroscience. "There is so much activity in this area now, it has gotten its own name, separate from bioethics more gener...Pinatubo's rivers show the danger isn't over when volcanic eruption ends
...ted with devastating force in June 1991 and now is proving to be an ideal laboratory for studying the "hydrologic aftermath" of a volcanic eruption, said Karen Gran, a University of Washington doctoral student in Earth and space sciences. Gran has been studying data compiled from 1997 through 2003 from five...Gene sequencing explains bioremediation 'bug'
...rain 195 and other Dehalococcoides varieties are proving difficult to culture in the laboratory, the Cornell microbiologist acknowledges. Together, the academic and corporate researchers are learning more about Dehalococcoides husbandry. For example, it seems to like a cocktail of acetate, vitamin B-12 a...New drug may aid battle against nicotine addiction, Alzheimer's and other disorders
...omography, more commonly known as PET scans. After proving the drug's effectiveness, Mukherjee believes the drug will have implications for other conditions, as well. Study results appear in the January issue of the "Journal of Nuclear Medicine." "Nifrolidine is suited to provide reliable, quantitative info...Scientists decipher genome of fungus that can cause life-threatening infections
...ic sequence and transcriptome analysis are already proving to be invaluable to researchers working to understand and cure this infectious disease." He says the genome sequence has enabled more rapid gene identification, fueled genome wide insertional mutagenesis approaches, and provided the foundation for th...Scientists detect probable genetic cause of some Parkinson's disease cases
...arge group of families and sibling pairs, which is proving to be an invaluable resource for these studies," says Diane Murphy, Ph.D., a program director at NINDS. "Because the prevalence of this mutation is 5 percent in families with a history of the disease and it is relatively common even among those witho...UBC prof's research challenges prevailing theory of how new species evolve
...peciation by distance.'" Part of the difficulty in proving the theory has been that few examples of such species are known today. The greenish warbler, living throughout Asia, and the Ensatina salamander found in mountains in North America's west coast, are the only known clear examples of species that may h...Protein stops growth of brain tumor, OHSU study shows
...nhibitor," Clinton noted. "This is another step in proving it doesn't kill all cells, and the more specific and tailored it is to a particular molecular profile, the less likely you're going to have a lot of side effects."...UCLA scientists transform HIV into cancer-seeking missile
...ause pain or harm to the animal. Though excited at proving that HIV can be used to target cancer cells, Chen emphasizes that the carrier must be further enhanced for safety and specificity before it can be tested as a gene-therapy method in humans. "Our next step will be to test whether we can direct thera...Green tea extract shows promise as an anti-cancer agent, UCLA study finds
...tea extract has potential as an anti-cancer agent, proving for the first time that it is able to target cancer cells while leaving healthy cells alone. The study, published in the Feb. 15, 2005 issue of the peer-reviewed journal Clinical Cancer Research, also uncovered more about how green tea extract works...New DNA studies verify existence of three right whale species
...even stronger support for this taxonomic revision, proving that both types of genetic material can be used in tandem to test and revise species classifications and subsequently redirect conservation efforts for those populations most in need." Traditionally, mitochondrial DNA has been the preferred marker f...Fox Chase Cancer Center scientists identify immune-system mutation
... Known as "helper deficient" or HD mice, they are proving to be useful for exploring the pathways of lymphocyte development, according to Kappes. Helper T cells, so called because they arise from the thymus gland, are essential for combating intracellular viral and bacterial infections (cell-mediated immuni...'Hobbit' fossil likely represents new branch on human family tree
...ls, fire, and a pygmy elephant, suggesting but not proving that Homo floresiensis may have had surprisingly advanced cognitive abilities given its chimpanzee-sized brain....Scientists discover that host cell lipids facilitate bacterial movement
... treated with molecules that inhibited PI3-kinase, proving that Listeria depend on PI3-kinase to move. "Our studies show that Listeria is capable of inside-out signaling," explains Dr. Southwick. "Most signals arise from molecules binding receptors on the outside of the cell. In the case of Listeria, we fin...NJIT Presidential Award winner takes stem cell research another step
...olds, can help regenerate bone growth; and another proving that stem cells taken from one person can be successfully implanted into another. A list of conditions for which stem-cell treatment holds promise grows almost daily: It now includes Parkinson's, diabetes, Alzheimer's, cancer and traumatic brain inj...