Abnormal fat metabolism underlies heart problems in diabetic patients
... set of techniques that allow them to separate and quantify thousands of different lipids based on their subtle structural differences. The set of techniques has been termed "shotgun lipidomics" because they very rapidly determine which lipids are in tissues and blood. "Shotgun lipidomics provide a precise wa...Gilbert Foundation and American Fed for Aging Research award grants on Alzheimer's disease
...on of the disease. Dr. Boutauds research seeks to quantify whether levels of secreted APP alpha and beta could serve as an effective biomarker for Alzheimers disease. This biomarker could potentially be used as a prognostic tool to track the progression of the disease as well as monitor the biological effec...Story tips from the US Department of Energy's Oak Ridge National Laboratory, August 2007
...r Ogeechee River system have prompted an effort to quantify the causes and prioritize recovery efforts. Yetta Jager and colleagues at Oak Ridge National Laboratory are conducting a population viability analysis, which will provide a scientific basis for assessing cumulative and separate effects of factors tho...See what you're spewing as you speed along
...ions components. The next steps will be to fully quantify the technique and add additional lasers for other key emissions such as nitrogen oxide, nitrogen dioxide and specific hydrocarbons. ...How cells change the pace of their steps
...he field is the ability to effectively measure and quantify the mechanical forces that cells use to move, said Richard Firtel, a professor of cell and developmental biology in UCSDs Division of Biological Sciences who co-directed the motility study with Lasheras. Our study not only makes a major advance in un...New survey documents the headaches of computerized medicine
... had been using CPOE. The survey was the first to quantify the breadth and importance of CPOEs unintended consequences. The survey results were described in a research paper published in the July/August issue of the peer-reviewed Journal of the American Medical Informatics Association. [The Extent and Import...Chickens dieting to help Delaware waterways
...ke advantage of the enzyme. It's also helped us to quantify the reduction of phosphorus to the environment. William Vanderwende, chairperson of the state's Nutrient Management Commission, said he has been contacted by several states who want to model their nutrient management program after Delaware's. Whi...Carnegie Mellon scientists find key HIV protein makes cell membranes bend more easily
...y, a cell membrane resists bending. Scientists can quantify the energy needed to overcome this resistance. The Carnegie Mellon team found that FP-23 reduces the energy required to penetrate an artificial cell membrane by up to 13 fold, depending on the thickness of that membrane. Reducing this energy should ...Measuring the unseeable: Penn researchers probe proteins' dark energy
...it. We figured out how to see it and have begun to quantify the so-called dark energy of proteins. Proteins are malleable in shape and internal structure, which enables them to twist and turn to bind with other proteins. The motions that we are looking at are very small, but very fast, on the time scale of ...New research seeks to enhance alternative fuel integration in public vehicle fleets
...ry and field studies on the Countys green fleet to quantify the impact of ethanol on propulsion system durability, reliability, vehicle availability and life-cycle cost. CIMS will also be looking to work with regional technology companies seeking to test, validate and launch alternative energy products. Add...Chronically sleep deprived? You can't make up for lost sleep
...and muscle activity patterns in order to precisely quantify sleep-wake patterns. After the first day of sleep loss, animals compensated by increasing their intensity, or depth, of sleep, which is indicative of a homeostatic response. However, on the subsequent days of sleep loss, the animals failed to gener...Desertification: UN experts prescribe global policy overhaul to avoid looming mass migrations
...loomy picture. However it is difficult to properly quantify the number of environmental migrants and the migration routes as long as the concept itself remains debated even from a scientific point of view, the analysis says. UNU advances a classification scheme based on three subgroups of migrants driven pr...Salvage logging, replanting increased biscuit fire severity
...oncludes. The analysis, one of the first to ever quantify the effect of salvage logging and replanting on future fire severity, is being published this week in Proceedings of the National Academy of Sciences, a professional journal. It found that fire severity was 16 to 61 percent higher in logged and pla...What's going on in the body? Advanced time-of-flight PET takes a superior 'look'
...ned without jeopardizing the ability to detect and quantify cancer," she added. "In some cases, TOF/PET detected lesions that are missed with conventional PET," said Perkins. ...Researchers develop way to calculate speed of bacterial sex
...teria hangouts. This model will help scientists to quantify the spread of important bacterial traits. The swapping of genetic material between bacteria leads to bacterial adaptation and evolution; however, bacterial adaptation is a double-edged sword for the environment. While the genetic exchange among bac...Heavy multivitamin use may be linked to advanced prostate cancer
...ividual supplements, we were unable to identify or quantify individual components responsible for the associations that we observed, the authors write. In an accompanying editorial, Goran Bjelakovic, M.D., of the University of Nis in Serbia, and Christian Gluud, M.D., of Copenhagen University Hospital in D...Other highlights in the May 16 JNCI
...a, are at a high risk for secondary cancers. To quantify this risk, Milena Maule, Ph.D., of the University of Turin in Italy, and colleagues compared the rates of second cancers in survivors of childhood leukemia and lymphoma with the cancer rate in the general population. They used a very large dataset th...DOE JGI sets 'gold standard' for metagenomic data analysis
...ced isolate organisms. This approach allowed us to quantify the fidelity of several data processing methods, since we could identify the correct answer by comparing the synthetic datasets to the corresponding isolate genomes." "This paper provides an extremely useful survey of tools and existing approaches ...UCLA AIDS Institute researchers find a peptide that encourages HIV infection
... order. The researchers had initially wanted to quantify previous research by Dr. Robert I. Lehrer, distinguished professor of medicine in the division of infectious diseases at the David Geffen School of Medicine at UCLA and a co-author of the present study. Unexpectedly, the researchers discovered that w...Enhanced MR-guided focused ultrasound guidelines demonstrate improved efficacy and durability
...ines. The symptom severity score (SSS) was used to quantify the results. 86% of patients treated with commercial treatment guidelines sustained a 10-point or greater improvement in SSS by 12 months compared with 84% of patients treated with expanded treatment guidelines and 71% of patients treated with pi...